Results 51 to 60 of about 6,670 (185)
International Journal of Molecular Sciences, 2022 Isoquercitrin (IQC) is a component abundantly present in many plants and is known to have an anti-viral effect against various viruses. In this study, we demonstrate that IQC exhibits strong anti-influenza A virus infection, and its effect is closely related to the suppression of hemagglutinin (HA) and neuraminidase (NA) activities.
Won-Kyung Cho +2 more
openaire +2 more sources
Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit
mBio, 2019 Human antibody-based immunity to influenza A virus is limited by antigenic drift resulting from amino acid substitutions in the hemagglutinin (HA) head domain.
Meghan O. Altman +10 more
doaj +1 more source
Viral factors in influenza pandemic risk assessment [PDF]
, 2016 The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans.
Barclay, Wendy +18 more
core +4 more sources
Virology, 2010 The avian influenza viruses (AIVs) can be highly contagious to poultry and a zoonotic threat to humans. Since the memory CD8(+) T lymphocyte responses in chickens to AIV proteins have not been defined, these responses to H5N9 AIV hemagglutinin (HA) and nucleocapsid (NP) proteins were evaluated by ex vivo stimulation with virus infected non-professional
Singh, Shailbala +3 more
openaire +2 more sources
Receptor binding specificity of recent human H3N2 influenza viruses
Virology Journal, 2007 Background Human influenza viruses are known to bind to sialic acid linked α2-6 to galactose, but the binding specificity beyond that linkage has not been systematically examined.
Cummings Richard D +5 more
doaj +1 more source
Cytomegalovirus is associated with depression and anxiety in older adults [PDF]
, 2008 Infection with cytomegalovirus (CMV), a β-herpesvirus, is common within the population. Although asymptomatic, infection is associated with increased serum concentrations of cytokines such as TNFα and IL-6, which are also related to mood and wellbeing ...
Akbar +35 more
core +1 more source
FEBS Letters, 1993 Hygromycin B was encapsulated in reconstituted Sendai viral envelopes containing only the fusion (F) protein (F‐virosomes). Incubation of loaded F‐virosomes with cultured HepG2 cells resulted in fusion mediated delivery of hygromycin B to the cell cytoplasm, as was inferred from inhibition of DNA synthesis. Binding of the F‐virosomes to HepG2 cells was
Bagai, Sangeeta, Sarkar, Debi P.
openaire +2 more sources
Unexpected interfarm transmission dynamics during a highly pathogenic avian influenza epidemic [PDF]
, 2016 Next-generation sequencing technology is now being increasingly applied to study the within- and between-host population dynamics of viruses. However, information on avian influenza virus evolution and transmission during a naturally occurring epidemic ...
Bonfanti, Lebana +12 more
core +1 more source
Nature CommunicationsConserved epitopes shared between virus subtypes are often subdominant, making it difficult to induce broadly reactive antibodies by immunization. Here, we generate a plasmid DNA mix vaccine that encodes protein heterodimers with sixteen different ...
Daniëla Maria Hinke +9 more
doaj +1 more source
Application of Species Distribution Modeling for Avian Influenza surveillance in the United States considering the North America Migratory Flyways. [PDF]
, 2016 Highly Pathogenic Avian Influenza (HPAI) has recently (2014-2015) re-emerged in the United States (US) causing the largest outbreak in US history with 232 outbreaks and an estimated economic impact of $950 million.
Alkhamis, Moh A +2 more
core +1 more source