Results 51 to 60 of about 11,301 (222)

Dangerous universal donors: the reality of the Hemocentro in Belo Horizonte, Minas Gerais

Revista Brasileira de Hematologia e Hemoterapia
BACKGROUND: The term dangerous universal blood donor refers to potential agglutination of the erythrocytes of non-O recipients due to plasma of an O blood group donor, which contains high titers of anti-A and/or anti-B hemagglutinins.
Mariana Martins Godin, Lucas de Oliveira Souza, Luciana Cayres Schmidt, Lauro Mello Vieira, Rejane Silva Diniz, Luci Maria SantAna Dusse   +5 more
doaj   +1 more source

Neutralizing immune responses induced by oligomeric H5N1-hemagglutinins from plants

Veterinary Research, 2017
Plant-based transient expression is an alternative platform to produce hemagglutinin-based subunit vaccines. This production system provides not only fast and effective response in the context of a pandemic but also enables the supply of big volume ...
Hoang Trong Phan, Thuong Thi Ho, Ha Hoang Chu, Trang Huyen Vu, Ulrike Gresch, Udo Conrad   +5 more
doaj   +1 more source

Lectins and Tetrahymena – A review [PDF]

, 2016
The unicellular ciliate Tetrahymena is a complete organism, one of the most highly developed protozoans, which has specialized organelles performing each of the functions characteristic to the cells of higher ranked animals.
Csaba, György
core   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, EarlyView.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1

Annals of Neurology, EarlyView.
Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan, Milo Fonville, Mabel Hoekstra, Rolf Fronczek, Joost Smolders, Dick F. Swaab   +5 more
wiley   +1 more source

Simultaneous measurements of auto-immune and infectious disease specific antibodies using a high throughput multiplexing tool. [PDF]

PLoS ONE, 2012
Considering importance of ganglioside antibodies as biomarkers in various immune-mediated neuropathies and neurological disorders, we developed a high throughput multiplexing tool for the assessment of gangliosides-specific antibodies based on Biolpex ...
Atul Asati, Olga Kachurina, Anatoly Kachurin   +2 more
doaj   +1 more source

Synthetic vaccine affords full protection to mice against lethal challenge of influenza B virus of both genetic lineages

iScience, 2021
Summary: A quarter of all seasonal influenza cases are caused by type B influenza virus (IBV) that also dominates periodically. Here, we investigated a recombinant adenovirus vaccine carrying a synthetic HA2 representing the consensus sequence of all IBV
Caroline Gravel, Abenaya Muralidharan, Amparo Duran, Adrian Zetner, Annabelle Pfeifle, Wanyue Zhang, Anwar Hashem, Levi Tamming, Aaron Farnsworth, Hugues Loemba, Wangxue Chen, Florian Krammer, David Safronetz, Jingxin Cao, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Gary Van Domselaar, Xuguang Li   +18 more
doaj   +1 more source

Nanostructured Lipid Carriers Overcome the Low Immunogenicity of M2e Peptide via Surface Click Chemistry Conjugation, Improving the Anti‐M2e Antibody Response

Advanced NanoBiomed Research, EarlyView.
1) Nanostructured lipid carriers efficiently vectorize low‐immunogenic M2e peptide. 2) M2e peptide conjugation via click chemistry preserves the peptide key epitopes. 3) Forty M2e peptides per nanoparticle are sufficient to induce robust immune responses.
Louis Bourlon, Carole Fournier, Antoine Hoang, Christine Charrat, Alban Lepetitcolin, Jessica Morlieras, Fabrice Navarro, Patrice N. Marche   +7 more
wiley   +1 more source

Staphylococcus saprophyticus hemagglutinin binds fibronectin [PDF]

Infection and Immunity, 1994
Attachment of microorganisms to host tissue is regarded as an important step in the pathogenesis of infections. Staphylococcus saprophyticus adheres to various epithelial cells and hemagglutinates sheep erythrocytes. The hemagglutinin has been identified, but a human target for this surface protein is still not known.
S, Gatermann, H G, Meyer
openaire   +2 more sources

Presence of a low molecular weight lectin in the coelomic fluid of the sea urchin Paracentrotus lividus [PDF]

Invertebrate Survival Journal, 2009
A low molecular weight (MW) lectin (Paracentrotus lividus small lectin, PlSL) has been found in the sea urchin, Paracentrotus lividus. After gel electrophoresis under denaturing conditions, PlSL exhibits a MW of 13 kDa, while its hemagglutinating ...
F Drago, D Malagoli, F M Pezzino, V D’Urso, F Sammartano   +4 more
doaj   +1 more source