Results 221 to 230 of about 395,898 (355)

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia. [PDF]

Nat Commun
Lidonnici MR, Chianella G, Mende N, Bastos HP, Barcella M, Merelli I, Storto M, Romeo V, Tiboni F, Scaramuzza S, Rossi C, Raggi L, Aprile A, Crippa S, Iskander D, Roberts I, Karamiditris A, Keith J, Lechauve C, Weiss MJ, Wilson NK, Göttgens B, Bernardo ME, Ciceri F, Aiuti A, Marktel S, Laurenti E, Ferrari G.   +27 more
europepmc   +1 more source

A Novel Therapeutic Strategy for Bone Marrow Failure: Niche Rejuvenation Using Costal Cartilage‐Derived Stem Cells

Advanced Science, EarlyView.
CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong, Zhiguo Ling, Pengyuan Fan, Debao Li, Jinsong Wang, Wenjiong Shi, Rui Zuo, Runfeng Chen, Xuemin Sun, Lang Xiao, Yushi Ran, Shucheng Huang, Yi Tian, Chao Zhang, Yuzhang Wu, Bing Ni, Yi Zhang   +16 more
wiley   +1 more source

Targeted depletion of dysfunctional hematopoietic stem cells mitigates myeloid-biased differentiation in aged mice. [PDF]

Cell Discov
Ren X, Wang Y, Zhang Y.
europepmc   +1 more source

A human beta-globin gene fused to the human beta-globin locus control region is expressed at high levels in erythroid cells of mice engrafted with retrovirus-transduced hematopoietic stem cells [PDF]

, 1993
I Plavec, T Papayannopoulou, Chantal Maury, F. Meyer   +3 more
openalex   +1 more source

Blood signals: from birth to disease and death

, 2014
Bowman, T., Flores-Figueroa, E., King, K., Kokkaliaris, K., Lessard, J., Trompouki, E., Will, B.   +6 more
core   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

The influence of high-fat diet and energy-restricted diet on hematopoietic stem cells: mechanisms and implications. [PDF]

Front Immunol
Chen Z, Ang H, Li J, Yu M, Chen X, Wang L.   +5 more
europepmc   +1 more source

Intensive Chemoradiotherapy and Autologous Hematopoietic Stem Cell Transplantation in the Treatment of Lymphoma [PDF]

, 1991
Joseph W. Fay
openalex   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Post-traumatic growth experience with kinship hematopoietic stem cells transplantation in patients with aplastic anemia: A qualitative study. [PDF]

PLoS One
Huang X, Xu Y, Pan Y, Ye M, Liu T, Xu M.
europepmc   +1 more source