Results 231 to 240 of about 1,207,844 (359)

Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.

Cell Stem Cell, 2013
K. Takubo, Go Nagamatsu, C. Kobayashi, A. Nakamura-Ishizu, Hiroshi Kobayashi, Eiji Ikeda, N. Goda, Y. Rahimi, R. Johnson, T. Soga, A. Hirao, M. Suematsu, T. Suda   +12 more
semanticscholar   +1 more source

The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation

American Journal of Hematology, EarlyView.
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao, Nicolas Stocker, Béatrice Gaugler, Mohamad Mohty, Florent Malard   +4 more
wiley   +1 more source

Heritable ER stress impairs mitochondrial metabolism and maintenance of hematopoietic stem cells after low-dose irradiation. [PDF]

iScience
Moreno SG, Ferri F, Lewandowski D, Barroca V, Devanand S, Dechamps N, Romeo PH, Gault N.   +7 more
europepmc   +1 more source

Differentiation and proliferation of hematopoietic stem cells.

Blood, 1993
M. Ogawa
semanticscholar   +1 more source

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi, Michael Kutsche, Helena Lichtenfeld, Fanny Kortüm, Angela Abicht, Laura Herrmann, Theresia Herget   +6 more
wiley   +1 more source

In situ gene editing of hematopoietic stem cells via AAV-delivered CRISPR guide RNAs. [PDF]

Blood Adv
Karimzadeh A, Kim R, Garcia V, Florea M, Peacker BL, Kobayashi S, Watkins D, Messemer K, Zeng J, Bauer DE, Serwold T, Wagers AJ.   +11 more
europepmc   +1 more source

Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals.

Blood, 2007
M. Yoder, L. Mead, D. Prater, Theresa R. Krier, Karim N Mroueh, Fang Li, Rachel Krasich, C. Temm, J. Prchal, D. Ingram   +9 more
semanticscholar   +1 more source

The Critical Role of Fractionated Urine Glycosaminoglycans in the Evaluation of Mucopolysaccharidosis Type II in Four Unrelated Families

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Since 2015, Ann and Robert H. Lurie Children's Hospital has performed diagnostic testing for infants who screen positive for mucopolysaccharidosis type II (MPS II) on the Illinois newborn screen. Preliminary diagnostic testing includes measurement of plasma iduronate‐2‐sulfatase enzyme activity and urinary glycosaminoglycan analysis, followed ...
Carly A. Rasmussen, Monika Izdebski, Allison Paltzer, Rachel Hickey, Laura Pollard, Joshua Baker   +5 more
wiley   +1 more source

Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells

Circulation Research, 2015
G. Courties, F. Herisson, H. Sager, T. Heidt, Yuxiang Ye, Ying Wei, Yuan Sun, N. Severe, Partha Dutta, Jennifer Scharff, D. Scadden, R. Weissleder, F. Swirski, M. Moskowitz, M. Nahrendorf   +14 more
semanticscholar   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source