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Hematopoietic stem-cell differentiation
Current Opinion in Immunology, 1991Hematopoietic stem cells can be identified and isolated from hematopoietic tissues of mammalian hosts. Assay systems that solely reflect hematopoietic stem cell activity are being developed, and new cytokines that influence hematopoietic stem-cell proliferation and differentiation have been described.
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Hematopoietic Stem-Cell Transplantation
New England Journal of Medicine, 2006Hematopoietic stem-cell transplantation, which is used to treat both malignant and nonmalignant conditions, was first conceived more than 50 years ago, but problems associated with transplanting a nonsolid organ and modulating the immune response had to be solved before the procedure could be used clinically.
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Mobilization of hematopoietic stem cells
Blood Reviews, 2000Hematopoietic stem cell transplantation has been extensively exploited as a therapeutic and research modality and has revolutionized current patient care. At present, more and more medical centers use peripheral blood progenitor cells for transplantation by mobilizing hematopoietic stem cells from bone marrow to peripheral blood because of potential ...
S, Fu, J, Liesveld
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The biology of hematopoietic stem cells
Archives of Medical Research, 2003Rarely has so much interest from the lay public, government, biotechnology industry, and special interest groups been focused on the biology and clinical applications of a single type of human cell as is today on stem cells, the founder cells that sustain many, if not all, tissues and organs in the body.
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Hematopoietic stem cells: An overview
Transfusion and Apheresis Science, 2014Considerable efforts have been made in recent years in understanding the mechanisms that govern hematopoietic stem cell (HSC) origin, development, differentiation, self-renewal, aging, trafficking, plasticity and transdifferentiation. Hematopoiesis occurs in sequential waves in distinct anatomical locations during development and these shifts in ...
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INTRAEMBRYONIC HEMATOPOIETIC STEM CELLS
Hematology/Oncology Clinics of North America, 1997Intraembryonic hematopoietic stem cells (HSC) were first detected in avian chimeras associating an embryo with a yolk sac (YS). Cell markers were used to construct chimeras. The results showed that YS blood precursors undergo primitive erythropoiesis and become extinct, whereas intraembryonic precursors colonize rudiments of blood-forming organs and ...
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Human hematopoietic stem cell vulnerability to ferroptosis
Cell, 2023Clary B Clish, Vijay G Sankaran
exaly
Hematopoietic Stem Cell Transplantation
Clinical Journal of Oncology Nursing, 2004Nonniekaye Shelburne +2 more
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Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
Cell Stem Cell, 2021Matthew A Loberg +2 more
exaly