Results 271 to 280 of about 395,898 (355)

Efficacy and Safety of the Third‐Generation Tyrosine Kinase Inhibitor Olverembatinib in Combination With Inotuzumab Ozogamicin for the Treatment of Adult Philadelphia Chromosome‐Positive Acute Lymphoblastic Leukemia Patients With Refractory/Relapsed Disease or Persistent Minimal Residual Disease Bridging to Hematopoietic Stem Cell Transplantation

American Journal of Hematology, EarlyView.
Xiaoyu Zhang, Yigeng Cao, Jialin Wei, Weihua Zhai, Qiaoling Ma, Chen Liang, Xin Chen, Wenbin Cao, Donglin Yang, Aiming Pang, Yi He, Sizhou Feng, Mingzhe Han, Rongli Zhang, Erlie Jiang   +14 more
wiley   +1 more source

Monocyte‐derived macrophages‐synovial fibroblasts crosstalk unravels oncostatin signaling network as a driver of synovitis in osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origins and functions of diverse macrophage subsets seeding the synovial joint tissue remain incompletely understood.
Damien Laouteouet, Olivier Bortolotti, Léa Marineche, Nicole Hannemann, Manon Chambon, Yaël Glasson, Anne‐Sophie Dumé, Julien De Lima, Maud Fournial, Dylan Touchet, Dany Séverac, Felicia Leccia, Christophe Duperray, Henri‐Alexandre Michaud, Farida Djouad, Benoît Le Goff, Frédéric Blanchard, Florence Apparailly, Gabriel Courties   +18 more
wiley   +1 more source

Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesis. [PDF]

Science
Phan J, Chen B, Zhao Z, Allies G, Iannaccone A, Paul A, Cansiz F, Spina A, Leven AS, Gellhaus A, Schadendorf D, Kimmig R, Mettlen M, Tasdogan A, Morrison SJ.   +14 more
europepmc   +1 more source

B cells and systemic sclerosis interstitial lung disease

Arthritis &Rheumatology, Accepted Article.
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman, Voon Ong, Christopher Denton   +2 more
wiley   +1 more source

Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells. [PDF]

PLoS Biol
Chen X, Tober J, Dominguez M, Tang AT, Bockman J, Yang J, Mani S, Lee CN, Chen M, Thillaikumaran T, Mericko-Ishizuka P, Mainigi M, Speck NA, Kahn ML.   +13 more
europepmc   +1 more source

From Inception to Innovation: 20 Years of Nanoarchitectonics

Chemistry – An Asian Journal, EarlyView.
Although nanotechnology was founded in the 20th century, the term nanoarchitectonics was first coined at the turn of the 21st century. Therefore, nanoarchitectonics has a history of about 20 years. In this review article, we will provide an overview of nanoarchitectonics through examining some research examples on manipulation‐based nanoarchitectonics ...
Katsuhiko Ariga, Jingwen Song, Kohsaku Kawakami   +2 more
wiley   +1 more source

Astragaloside IV accelerates hematopoietic reconstruction by improving the AMPK/PGC1α-mediated mitochondrial function in hematopoietic stem cells. [PDF]

Chin Med
Zhang L, Xu W, Zeng Y, Wang L, Luo J, Zhou X, Mei Q, Qin D, Wu A, Wu J, Huang F.   +10 more
europepmc   +1 more source

Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells [PDF]

, 2019
Abou-Ezzi, Grazia, Cancilla, Daniel, Celik, Hamza, Chendamarai, Ezhilarasi, Christ, Stephanie, Dipersio, John F, Eissenberg, Linda G, et al,, Gao, Feng, Gehrs, Leah, Holt, Matthew, Karpova, Darja, Link, Daniel C, Rettig, Michael P, Ritchey, Julie, Ruminski, Peter G, Yang, Wei, Zhang, Jingzhu   +17 more
core   +1 more source

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

British Journal of Clinical Pharmacology, EarlyView.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens, Olivier J. M. Béquignon, Stefanie D. Krens, Mark Löwenberg, Martine E. D. Chamuleau, Remco J. Molenaar, Anita M. G. Kramers, Marianne A. Kuijvenhoven, Imke H. Bartelink   +8 more
wiley   +1 more source

Bone marrow niches for hematopoietic stem cells. [PDF]

Hemasphere
Pereira AL, Galli S, Nombela-Arrieta C.
europepmc   +1 more source