Results 11 to 20 of about 428,654 (353)
Blood, 2021 Sickle cell disease (SCD) is characterized by increased hemolysis which results in plasma heme overload and ultimately cardiovascular complications. Here, we hypothesized that increased heme in SCD causes upregulation of heme oxygenase 1 (Hmox1) which ...
Archita V. Menon +6 more
semanticscholar +1 more source
Biology, 2021 Introduction: Fibromyalgia (FM) affects 2.40% of the Spanish population. The most widespread treatment has been the combination of patient education, pain coping strategies and exercise. With regard to patient education, there are few previous studies on
María Mendoza-Muñoz +5 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance Heme availability in the cell enables the proper folding and function of enzymes, which carry heme as a cofactor. Using genome-scale modeling, we identified metabolic fluxes and genes that limit heme production.
O. P. Ishchuk +6 more
semanticscholar +1 more source
Microbiology Spectrum, 2022 Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially cytotoxic. Since M.
Rebecca K. Donegan +11 more
doaj +1 more source
Relación existente entre la ratio 2D:4D y la composición corporal en adolescentes de Extremadura
E-Motion, 2020 Introducción: La ratio 2D:4D es el cociente entre la longitud del dedo índice y anular de la mano, asociada al balance entre andrógenos y estrógenos, durante el desarrollo embrionario. Una baja proporción 2D:4D, refleja niveles más altos de testosterona
Maria Mendoza Muñoz +3 more
doaj +1 more source
Molecular Taphonomy of Heme: Chemical Degradation of Hemin under Presumed Fossilization Conditions
Molecules, 2023 The metalloporphyrin heme acts as the oxygen-complexing prosthetic group of hemoglobin in blood. Heme has been noted to survive for many millions of years in fossils. Here, we investigate its stability and degradation under various conditions expected to
Mariam Tahoun +4 more
doaj +1 more source
The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease
Frontiers in Immunology, 2021 Hemolysis is a pathological feature of several diseases of diverse etiology such as hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the release of large quantities of hemoglobin into the blood circulation and the ...
Oluwabukola T Gbotosho +2 more
semanticscholar +1 more source
Molecules, 2022 The rich source of heme within malarial parasites has been considered to underly the action specificity of artemisinin. We reasoned that increasing intraparasitic free heme levels might further sensitize the parasites to artemisinin.
Pan Zhu, Bing Zhou
doaj +1 more source
Influence of Body Composition on Physical Fitness in Adolescents
Medicina, 2020 Background and objectives: Childhood obesity is one of the main public health issues facing advanced societies. The Spanish population presents 28.6% overweight or obese adolescents, and Extremadura, 22.3%.
María Mendoza-Muñoz +5 more
doaj +1 more source
Nanomaterials, 2023 Hemeprotein detection has motivated extensive research on the direct reaction of a heme molecule and a redox dye. The present study used methylene blue as both donor and acceptor for a redox reaction.
Porntip Khownarumit +5 more
doaj +1 more source