Results 21 to 30 of about 414,627 (398)

The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease

open access: yesFrontiers in Immunology, 2021
Hemolysis is a pathological feature of several diseases of diverse etiology such as hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the release of large quantities of hemoglobin into the blood circulation and the ...
O. Gbotosho, M. Kapetanaki, G. Kato
semanticscholar   +1 more source

Influence of Body Composition on Physical Fitness in Adolescents

open access: yesMedicina, 2020
Background and objectives: Childhood obesity is one of the main public health issues facing advanced societies. The Spanish population presents 28.6% overweight or obese adolescents, and Extremadura, 22.3%.
María Mendoza-Muñoz   +5 more
doaj   +1 more source

Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS).
Yaschar Kabiri   +12 more
doaj   +1 more source

COVID-19:Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism

open access: yes, 2020
The novel coronavirus pneumonia (COVID-19) is an infectious acute respiratory caused by the novel coronavirus. The virus is the positive-strand RNA one with high homology to bat coronavirus.
Wenzhong Liu, Hualan Li
semanticscholar   +1 more source

Involvement of Small Colony Variant-Related Heme Biosynthesis Genes in Staphylococcus aureus Persister Formation in vitro

open access: yesFrontiers in Microbiology, 2021
Background: Persisters are important reasons for persistent infections, and they can lead to antibiotic treatment failure in patients and consequently chronic infection.
Xuyang Wang   +8 more
doaj   +1 more source

Peroxidase activity of erythrocytes hemoglobin under action of low-frequency vibration

open access: yesБіологічні студії, 2021
Background. Hemoglobin is a hemoprotein which in the presence of oxidative equivalents, such as H2O2, can act as peroxidase with a very high oxidative potential.
O. I. Dotsenko   +2 more
doaj   +1 more source

Pro-inflammatory Actions of Heme and Other Hemoglobin-Derived DAMPs

open access: yesFrontiers in Immunology, 2020
Damage associated molecular patterns (DAMPs) are endogenous molecules originate from damaged cells and tissues with the ability to trigger and/or modify innate immune responses.
M. Bozza, V. Jeney
semanticscholar   +1 more source

Analyzing magnetic bead QuantiGene® Plex 2.0 gene expression data in high throughput mode using QGprofiler

open access: yesBMC Bioinformatics, 2019
Background The QuantiGene® Plex 2.0 platform (ThermoFisher Scientific) combines bDNA with the Luminex/xMAP magnetic bead capturing technology to assess differential gene expression in a compound exposure setting.
Bie Verbist   +8 more
doaj   +1 more source

New Marker of Colon Cancer Risk Associated with Heme Intake: 1,4-Dihydroxynonane Mercapturic Acid [PDF]

open access: yes, 2006
Background: Red meat consumption is associated with an increased risk of colon cancer. Animal studies show that heme, found in red meat, promotes preneoplastic lesions in the colon, probably due to the oxidative properties of this compound.
Bingham, Sheila A.   +8 more
core   +3 more sources

The Multifaceted Role of Heme in Cancer

open access: yesFrontiers in Oncology, 2020
Heme, an iron-containing porphyrin, is of vital importance for cells due to its involvement in several biological processes, including oxygen transport, energy production and drug metabolism.
V. Fiorito   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy