Results 21 to 30 of about 413,473 (387)
The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease
Frontiers in Immunology, 2021 Hemolysis is a pathological feature of several diseases of diverse etiology such as hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the release of large quantities of hemoglobin into the blood circulation and the ...
O. Gbotosho, M. Kapetanaki, G. Kato
semanticscholar +1 more source
, 2020 The novel coronavirus pneumonia (COVID-19) is an infectious acute respiratory caused by the novel coronavirus. The virus is the positive-strand RNA one with high homology to bat coronavirus.
Wenzhong Liu, Hualan Li
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Pro-inflammatory Actions of Heme and Other Hemoglobin-Derived DAMPs
Frontiers in Immunology, 2020 Damage associated molecular patterns (DAMPs) are endogenous molecules originate from damaged cells and tissues with the ability to trigger and/or modify innate immune responses.
M. Bozza, V. Jeney
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Zinc supplementation improves heme biosynthesis in rats exposed to lead [PDF]
Universa Medicina, 2015 Background Lead acetate (Pb) inhibits heme biosynthesis through inhibition of d-aminolevulinic acid dehydrogenase (d-ALAD), copro porphyrinogen oxidase, and ferro chelatase. Zinc supplementation increases lead-binding metallothionein proteins.
Budi Santosa +3 more
doaj +1 more source
The Crystal Structure of the Extracellular 11-heme Cytochrome UndA Reveals a Conserved 10-heme Motif and Defined Binding Site for Soluble Iron Chelates [PDF]
, 2012 Members of the genus Shewanella translocate deca- or undeca-heme cytochromes to the external cell surface thus enabling respiration using extracellular minerals and polynuclear Fe(III) chelates.
Butt, Julea N. +7 more
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The Multifaceted Role of Heme in Cancer
Frontiers in Oncology, 2020 Heme, an iron-containing porphyrin, is of vital importance for cells due to its involvement in several biological processes, including oxygen transport, energy production and drug metabolism.
V. Fiorito +4 more
semanticscholar +1 more source
BMC Bioinformatics, 2019 Background The QuantiGene® Plex 2.0 platform (ThermoFisher Scientific) combines bDNA with the Luminex/xMAP magnetic bead capturing technology to assess differential gene expression in a compound exposure setting.
Bie Verbist +8 more
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Heme on Pulmonary Malaria: Friend or Foe?
Frontiers in Immunology, 2020 Malaria is a hemolytic disease that, in severe cases, can compromise multiple organs. Pulmonary distress is a common symptom observed in severe malaria caused by Plasmodium vivax or Plasmodium falciparum.
Tatiana Almeida Pádua +1 more
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Frontiers in Microbiology, 2021 The ability to obtain purified biliverdin IX (BVIX) isomers other than the commercially available BVIXα is limited due to the low yields obtained by the chemical coupled oxidation of heme.
Elizabeth A. Robinson +3 more
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From Synthesis to Utilization: The Ins and Outs of Mitochondrial Heme
Cells, 2020 Heme is a ubiquitous and essential iron containing metallo-organic cofactor required for virtually all aerobic life. Heme synthesis is initiated and completed in mitochondria, followed by certain covalent modifications and/or its delivery to apo ...
Samantha A. Swenson +5 more
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