Results 31 to 40 of about 153,280 (319)
Dietary iron, water intake and risk of urinary bladder cancer: a case-control study [PDF]
World Cancer Research Journal, 2020 Objective: Urinary bladder cancer (UBC) incidence and mortality in Uruguay show the highest rates in Latin America. Epidemiological research shows that iron and fluid intake have been inconsistently related to UBC risk regarding nutritional items.
A. Ronco, J. Calderón, B. Mendoza
doaj +1 more source
Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias
eLife, 2016 Porphyrias are disorders of heme metabolism frequently characterized by extreme photosensitivity. This symptom results from accumulation of porphyrins, tetrapyrrole intermediates in heme biosynthesis that generate reactive oxygen species when exposed to ...
Bradford M Stubenhaus +8 more
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The GluTR-binding protein is the heme-binding factor for feedback control of glutamyl-tRNA reductase
eLife, 2019 Synthesis of 5-aminolevulinic acid (ALA) is the rate-limiting step in tetrapyrrole biosynthesis in land plants. In photosynthetic eukaryotes and many bacteria, glutamyl-tRNA reductase (GluTR) is the most tightly controlled enzyme upstream of ALA.
Andreas S Richter +2 more
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Heme Catabolism and Heme Oxygenase in Neurodegenerative Disease
Antioxidants & Redox Signaling, 2004 Heme oxygenase, the rate-limiting step in heme catabolism, appears to play an important role in a number of neurodegenerative disorders, such as Alzheimer disease. Interestingly, the spatial distribution of heme oxygenase-1 expression in diseased brain is essentially identical to that of the pathological expression of tau, suggesting a key role for ...
Takeda, Atsushi +7 more
openaire +4 more sources
Heme oxygenation and the widening paradigm of heme degradation [PDF]
Archives of Biochemistry and Biophysics, 2014 Heme degradation through the action of heme oxygenase (HO) is unusual in that it utilizes heme as both a substrate and cofactor for its own degradation. HO catalyzes the oxygen-dependent degradation of heme to biliverdin with the release of CO and "free" iron.
Angela Wilks, Geoffrey Heinzl
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A Diffusion-Based Approach to Geminate Recombination of Heme Proteins with Small Ligands [PDF]
, 2002 A model of postphotodissociative monomolecular (geminate) recombination of heme proteins with small ligands (NO, O2 or CO) is represented. The non-exponential decay with time for the probability to find a heme in unbound state is interpreted in terms of diffusion-like migration of ligabs physics/0212040 and between protein cavities.
arxiv +1 more source
The Dirichlet problem for a class of prescribed curvature equations [PDF]
arXiv, 2022 In this paper, we consider the Dirichlet problem for a class of prescribed curvature equations. Both degenerate and non-degenerate cases are considered. The existence of the $C^{1,1}$ regular graphic hypersurfaces with prescribing a class of curvatures and constant boundary is proved for the degenerate case.
arxiv
Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation
Frontiers in Cell and Developmental Biology, 2021 Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS).
Yaschar Kabiri +12 more
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Frontiers in Microbiology, 2018 Bacterial manganese (Mn) oxidation is catalyzed by a diverse group of microbes and can affect the fate of other elements in the environment. Yet, we understand little about the enzymes that catalyze this reaction.
Michael Medina +7 more
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Frontiers in Microbiology, 2020 Ferric uptake regulator (Fur) is a transcriptional regulator playing a central role in iron homeostasis of many bacteria, and Fur inactivation commonly results in pleiotropic phenotypes.
Lulu Liu +5 more
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