Results 31 to 40 of about 414,309 (352)
Antimicrobial Agents and Chemotherapy, 2003 A recent Letter to the Editor (R. K. Haynes, D. Monti, D. Taramelli, N. Basilico, S. Parapini, and P. Olliaro, Letter, Antimicrob. Agents Chemother. 47:1175, 2003) presented cogent evidence that artemisinin and its derivatives do not inhibit hemozoin formation in vitro.
Haynes, Richard K. +5 more
openaire +5 more sources
Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation
Frontiers in Cell and Developmental Biology, 2021 Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS).
Yaschar Kabiri +12 more
doaj +1 more source
Journal of Biological Chemistry, 2013 Heme is a prosthetic group best known for roles in oxygen transport, oxidative catalysis, and respiratory electron transport. Recent years have seen the roles of heme extended to sensors of gases such as O2 and NO and cell redox state, and as mediators of cellular responses to changes in intracellular levels of these gases.
Girvan, Hazel M., Munro, Andrew W.
openaire +2 more sources
Pro-inflammatory Actions of Heme and Other Hemoglobin-Derived DAMPs
Frontiers in Immunology, 2020 Damage associated molecular patterns (DAMPs) are endogenous molecules originate from damaged cells and tissues with the ability to trigger and/or modify innate immune responses.
M. Bozza, V. Jeney
semanticscholar +1 more source
Frontiers in Microbiology, 2021 Background: Persisters are important reasons for persistent infections, and they can lead to antibiotic treatment failure in patients and consequently chronic infection.
Xuyang Wang +8 more
doaj +1 more source
Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon [PDF]
, 2015 Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits epithelial damage and compensatory hyperproliferation, leading to hyperplasia.
Clara Belzer +13 more
core +2 more sources
BMC Bioinformatics, 2019 Background The QuantiGene® Plex 2.0 platform (ThermoFisher Scientific) combines bDNA with the Luminex/xMAP magnetic bead capturing technology to assess differential gene expression in a compound exposure setting.
Bie Verbist +8 more
doaj +1 more source
Peroxidase activity of erythrocytes hemoglobin under action of low-frequency vibration
Біологічні студії, 2021 Background. Hemoglobin is a hemoprotein which in the presence of oxidative equivalents, such as H2O2, can act as peroxidase with a very high oxidative potential.
O. I. Dotsenko +2 more
doaj +1 more source
New Marker of Colon Cancer Risk Associated with Heme Intake: 1,4-Dihydroxynonane Mercapturic Acid [PDF]
, 2006 Background: Red meat consumption is associated with an increased risk of colon cancer. Animal studies show that heme, found in red meat, promotes preneoplastic lesions in the colon, probably due to the oxidative properties of this compound.
Bingham, Sheila A. +8 more
core +4 more sources
The Multifaceted Role of Heme in Cancer
Frontiers in Oncology, 2020 Heme, an iron-containing porphyrin, is of vital importance for cells due to its involvement in several biological processes, including oxygen transport, energy production and drug metabolism.
V. Fiorito +4 more
semanticscholar +1 more source