mBio, 2018 Staphylococcus aureus is responsible for a significant amount of devastating disease. Its ability to colonize the host and cause infection is supported by a variety of proteins that are dependent on the cofactor heme.
Jacob E. Choby +5 more
doaj +1 more source
Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation
Frontiers in Cell and Developmental Biology, 2021 Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS).
Yaschar Kabiri +12 more
doaj +1 more source
Resolution of Key Roles for the Distal Pocket Histidine in Cytochrome c Nitrite Reductases [PDF]
, 2015 Cytochrome c nitrite reductases perform a key step in the biogeochemical N-cycle by catalyzing the six-electron reduction of nitrite to ammonium. These multi-heme cytochromes contain a number of His/His ligated c-hemes for electron transfer and a ...
Burlat, Benedicte +7 more
core +5 more sources
Structure and function of the bacterial heterodimeric ABC transporter CydDC: stimulation of ATPase activity by thiol and heme compounds. [PDF]
, 2014 In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytochromes requires the ATP-binding cassette-type cysteine/GSH transporter, CydDC.
Baldwin, SA +9 more
core +3 more sources
A Diffusion-Based Approach to Geminate Recombination of Heme Proteins with Small Ligands [PDF]
, 2002 A model of postphotodissociative monomolecular (geminate) recombination of heme proteins with small ligands (NO, O2 or CO) is represented. The non-exponential decay with time for the probability to find a heme in unbound state is interpreted in terms of ...
Abadan +69 more
core +2 more sources
Frontiers in Microbiology, 2021 Background: Persisters are important reasons for persistent infections, and they can lead to antibiotic treatment failure in patients and consequently chronic infection.
Xuyang Wang +8 more
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Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression. [PDF]
, 2016 Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli.
Azuma, Junya +13 more
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Peroxidase activity of erythrocytes hemoglobin under action of low-frequency vibration
Біологічні студії, 2021 Background. Hemoglobin is a hemoprotein which in the presence of oxidative equivalents, such as H2O2, can act as peroxidase with a very high oxidative potential.
O. I. Dotsenko +2 more
doaj +1 more source
A mutant of Neurospora crassa deficient in cytochrome c heme lyase activity cannot import cytochrome c into mitochondria [PDF]
, 1988 The nuclear cyt-2-1 mutant of Neurospora crassa is characterized by a gross deficiency of cytochrome c (Bertrand, H., and Collins, R. A. (1978) Mol. Gen. Genet. 166, 1-13).
Drygas, Mariola E. +4 more
core +1 more source
Preliminary studies of biosynthesis of heme O and heme A in intraerythrocytic stages of P. falciparum [PDF]
, 2014 Intermediates of the isoprenoid metabolism can bind to heme groups. Heme is critical and its derivatives, heme O and heme A, are the main compounds of aerobic respiration. They are synthesized by farnesylation of heme groups by ?heme O synthase?
Cirulli, Brenda Analía +5 more
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