Results 121 to 130 of about 137,322 (324)

Generation of Heme Oxygenase-1-Transgenic Rats

Experimental Biology and Medicine, 2003
Heme oxygenase-1 (HO-1) expression protects cells from a variety of cellular insults and inhibits inflammation. However, its role in the regulation of immune responses has not yet been clearly established. We generated HO-1 transgenic rats to directly test the impact of HO-1 on the different immune mechanisms.
C, Braudeau, D, Bouchet, C, Toquet, L, Tesson, S, Ménoret, S, Iyer, C, Laboisse, D, Willis, A, Jarry, R, Buelow, I, Anegon, C, Chauveau   +11 more
openaire   +2 more sources

Coinfection between human immunodeficiency virus and tuberculosis: A consideration on ritonavir-related heme Oxygenase-1 pathway

Biomedical and Biotechnology Research Journal, 2019
Background: Human immunodeficiency virus (HIV) infection is an important infection seen worldwide. HIV-infected patients usually have impaired immune function and get infected with other concurrent infections.
Won Sriwijitalai, Viroj Wiwanitkit
doaj   +1 more source

Heme Oxygenase-1: Clinical Relevance in Ischemic Stroke

Current pharmaceutical design, 2018
Stroke is the second-leading cause of death and a leading cause of serious long-term disability worldwide, with an increasing global burden due to the growing and aging population.
D. Bereczki, J. Balla, D. Bereczki
semanticscholar   +1 more source

Molecular Mechanisms Used by Salmonella to Evade the Immune System [PDF]

, 2017
Human and animal pathogens are able to circumvent, at least temporarily, the sophisticated immune defenses of their hosts. Several serovars of the Gram-negative bacterium Salmonella enterica have been used as models for the study of pathogen-host ...
Bernal Bayard, Joaquín, Ramos Morales, Francisco   +1 more
core   +1 more source

The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer

Journal of Biological Chemistry, 2017
Mammals incorporate a major proportion of absorbed iron as heme, which is catabolized by the heme oxygenase 1 (HO1)–NADPH-cytochrome P450 reductase (CPR) complex into biliverdin, carbon monoxide, and ferrous iron.
I. Yanatori, D. Richardson, S. Toyokuni, F. Kishi   +3 more
semanticscholar   +1 more source

Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]

, 2019
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria, Costantino, Paolo, D'Erme, Maria, Francioso, Antonio, Gazzino, Roberta, Mancini, Patrizia, Mattioli, Roberto, Mosca, Luciana, Piacentini, Lucia, Trovato, Maurizio, Wessjohann, Ludger   +10 more
core   +1 more source

Heme oxygenase-1 system and gastrointestinal tumors

World Journal of Gastroenterology, 2010
Heme oxygenase-1 (HO-1) system catabolizes heme into three products: carbon monoxide, biliverdin/bilirubin and free iron. It is involved in many physiological and pathophysiological processes. A great deal of data has demonstrated the roles of HO-1 in the formation, growth and metastasis of tumors.
Lin, MCM, Kung, H, Zhu, X, Fan, WG, Li, DP   +4 more
openaire   +4 more sources

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Combined fluorometric analysis of biliverdin and bilirubin by the recombinant protein HUG

MethodsX
Biliverdin is a secondary metabolite of heme catabolism. It is formed by the reaction catalyzed by heme oxygenase, which converts the heme group contained in proteins such as hemoglobin, myoglobin, cytochromes, and catalase into biliverdin, iron (II) and
Federica Tramer, Paola Sist, Rocio Cardenas-Perez, Ranieri Urbani, Giulia Bortolussi, Sabina Passamonti   +5 more
doaj   +1 more source

Role of G{alpha}12 and G{alpha}13 as Novel Switches for the Activity of Nrf2, a Key Antioxidative Transcription Factor [PDF]

, 2007
G{alpha}12 and G{alpha}13 function as molecular regulators responding to extracellular stimuli. NF-E2-related factor 2 (Nrf2) is involved in a protective adaptive response to oxidative stress.
Cho, Min Kyung, Choi, Sangdun, Hwang, Jong-Ik, Ki, Sung Hwan, Kim, Sang Geon, Kim, Won Dong, Lee, Chang Ho   +6 more
core   +2 more sources