Results 171 to 180 of about 73,522 (298)

CMAH-Targeted Knock-In of Inducible Heme Oxygenase-1 and Constitutive CD47 in GGTA1-Knockout Pigs for Xenotransplantation. [PDF]

Xenotransplantation
Lee H, Kim SE, Lee WK, Oh M, Lee S, No JG, Park MR, Kim S, Do MH, Oh KB.   +9 more
europepmc   +1 more source

Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsaturated Lipids for Combined Antioxidant, Anti‐Apoptotic, and Neurotrophic Treatments

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Ionizable lipid nanoparticles target multiple pathological pathways in neurodegeneration. The designed self‐assembled materials undergo a pH‐triggered structural transformation from a cubosome/hexosome coexistence to a hexosome phase, enhancing intracellular delivery of a multi‐target phytochemical formulation. The antioxidant‐loaded pH‐responsive LNPs
Thelma Akanchise, Fucen Luo, Borislav Angelov, Yuru Deng, Angelina Angelova   +4 more
wiley   +1 more source

Reappraising heme oxygenase-1 as a ferroptosis modulator in atherosclerosis: a mechanism-focused review. [PDF]

Front Immunol
Xu J, Chen C, Yuan HY, Zhang YY, Wang CR, Xi X, Pan H, Li DH, Lu Y.   +8 more
europepmc   +1 more source

Imperatorin ameliorates myocardial ischemia‐reperfusion injury by inhibiting endoplasmic reticulum stress‐mediated apoptosis via the PI3K/AKT/Nrf2 pathway

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
By activating the PI3K/AKT/Nrf2 pathway, imperatorin can reduce endoplasmic reticulum stress and its mediated apoptosis in cardiomyocytes, improve the pathological changes of myocardial tissue, and thus improve myocardial ischemia/reperfusion injury.
Mingjun Han, Fan Yu, Huanhuan Li
wiley   +1 more source

Behavior and Musculoskeletal Effects of Chronic D-Galactose Treatment in Mice: Role of Heme Oxygenase-1. [PDF]

Biomolecules
Wahba S, Badmus OO, Wasson AR, Abdel-Hakeem EA, Ragy MM, Ibrahim HM, Rüedi-Bettschen D, Stec DE.   +7 more
europepmc   +1 more source

Programmed Cell Death in Chronic Rhinosinusitis

Clinical and Translational Allergy, Volume 16, Issue 6, June 2026.
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu, Junying Hu, Weigang Gan, Qi Wu, Bing Zhong, Feng Liu   +5 more
wiley   +1 more source

Control of renal central carbon metabolism by heme oxygenase-1. [PDF]

iScience
Guerra J, Jentho E, Schäuble S, Scicluna BP, Vivas W, Martínez-Alarcón D, Groth M, King E, Röstel F, Hirth G, Soares MP, Wiech T, Panagiotou G, Bauer M, Hoerr V, Weis S.   +15 more
europepmc   +1 more source

Exercise Intervention for REM Sleep Behavior Disorder in Parkinson's Disease: Mechanisms and Implications for Neurorehabilitation

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review systematically explores exercise as a multi‐target intervention for RBD, highlighting its mechanisms of action and regulatory effects on key pathophysiological processes. ABSTRACT Backgrounds REM sleep behavior disorder (RBD) is a prodromal non‐motor symptom of Parkinson's disease (PD) and other α‐synucleinopathies, affecting approximately ...
Xinhui Qiu, Zihui Wang, Ruixue Xu, Yiying Hu, Weidong Le   +4 more
wiley   +1 more source

Alpha7 nicotinic acetylcholine receptor activation attenuates allergic airway inflammation and is associated with heme oxygenase-1 induction. [PDF]

Front Immunol
Iriki J, Fukahori S, Obase Y, Nakamura Y, Umene R, Wu CH, Yamada Y, Takemoto S, Takazono T, Sakamoto N, Fukushima C, Nishino T, Mukae H, Inoue T.   +13 more
europepmc   +1 more source

Development and functional adaptation of intestinal macrophages across the lifespan

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
This article discusses intestinal macrophage development, including the influence of developmental origins and life stages; ontogeny and functional heterogeneity; preclinical and clinical evidence. Abstract Macrophages of the gastrointestinal system are central regulators of gut development, homeostasis and disease, yet their origin, functional ...
Baha Mustafa, Elisa L Hill‐Yardin, Sarah J Spencer   +2 more
wiley   +1 more source