Results 51 to 60 of about 133,631 (206)
Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023 Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman +6 more
wiley +1 more source
Heme oxygenase-1: emerging target of cancer therapy
Journal of Biomedical Sciences, 2015 Heme oxygenase-1 (HO-1) is a rate-limiting enzyme catalyzing oxidative degradation of cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in mammalian cells.
L. Chau
semanticscholar +1 more source
Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023 FA is a progressive neurodegenerative disorder, but the primary cause of death is heart disease which occurs in 60% of the patients. Several functions of frataxin have been proposed, but none of them fully explain why its deficiency causes the FA phenotypes nor why the most affected cell types are neurons and cardiomyocytes.
Mariana B. Angulo +6 more
wiley +1 more source
Molecular Dynamics Simulations of Cytochrome c un-folding in AOT Reverse Micelles: the first steps [PDF]
arXiv, 2009 This paper explores the reduced form of horse cytochrome c confined in reverse micelles (RM) of so-dium bis-(2-ethylhexyl) sulfosuccinate (AOT) in isooctane by molecular dynamics simulation. RMs of two sizes were constructed at a water content of Wo = [H2O]/[AOT] = 5.5 and 9.1.
arxiv
Curvature estimates for a class of Hessian type equations [PDF]
arXiv, 2020 In this paper, we establish the curvature estimates for a class of Hessian type equations. Some applications are also discussed.
arxiv
Second order estimates for convex solutions of degenerate $k$-Hessian equations [PDF]
arXiv, 2022 The $C^{1,1}$ estimate of the Dirichlet problem for degenerate $k$-Hessian equations with non-homogenous boundary conditions is an open problem, if the right hand side function $f$ is only assumed to satisfy $f^{1/(k-1)} \in C^{1,1}$. In this paper, we solve this problem for convex solutions defined in the strictly convex bounded domain.
arxiv
Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1.
Journal of Clinical Investigation, 2015 Subarachnoid hemorrhage (SAH) carries a 50% mortality rate. The extravasated erythrocytes that surround the brain contain heme, which, when released from damaged red blood cells, functions as a potent danger molecule that induces sterile tissue injury ...
N. Schallner +8 more
semanticscholar +1 more source
An Update: Enzymatic Synthesis for Industrial Applications
Angewandte Chemie International Edition, Accepted Article.Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer +4 more
wiley +1 more source
The Dirichlet problem for a class of Hessian type equations [PDF]
arXiv, 2014 We are concerned with the Dirichlet problem for a class of Hessian type equations. Applying some new methods we are able to establish the $C^2$ estimates for an approximating problem under essentially optimal structure conditions. Based on these estimates, the existence of classical solutions is proved.
arxiv
The Pogorelov estimates for degenerate curvature equations [PDF]
arXiv, 2022 We establish the Pogorelov type estimates for degenerate prescribed k-curvature equations as well as k-Hessian equations. Furthermore,we investigate the interior C1,1 regularity of the solutions for Dirichlet problems. These techniques also enable us to improve the existence theorem for an asymptotic Plateau type problem in hyperbolic space.
arxiv