Results 31 to 40 of about 2,013 (172)
New insights into the role of heme oxygenase-1 in acute kidney injury
Kidney Research and Clinical Practice, 2020 Acute kidney injury (AKI) is attended by injury-related biomarkers appearing in the urine and serum, decreased urine output, and impaired glomerular filtration rate.
Meryl Nath, Anupam Agarwal
doaj +1 more source
Open Chemistry, 2020 A unique method was used to synthesize extremely stable silver stearate nanoparticles (AgStNPs) incorporated in an organic-based monolith. The facile strategy was then used to selectively isolate hemeproteins, myoglobin (Myo)
Alzahrani Eman
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Mechanisms of Neuronal Damage in Acute Hepatic Porphyrias
Diagnostics, 2021 Porphyrias are a group of congenital and acquired diseases caused by an enzymatic impairment in the biosynthesis of heme. Depending on the specific enzyme involved, different types of porphyrias (i.e., chronic vs. acute, cutaneous vs.
Andrea Ricci +3 more
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Hypoxic Regulation of the Large-Conductance, Calcium and Voltage-Activated Potassium Channel, BK
Frontiers in Physiology, 2021 Hypoxia is a condition characterized by a reduction of cellular oxygen levels derived from alterations in oxygen balance. Hypoxic events trigger changes in cell-signaling cascades, oxidative stress, activation of pro-inflammatory molecules, and growth ...
Sara V. Ochoa +9 more
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The Plant Genome, Volume 16, Issue 2, June 2023., 2023 Abstract De novo purine biosynthesis is required for the incorporation of fixed nitrogen in ureide exporting nodules, as formed on soybean [Glycine max (L.) Merr.] roots. However, in many cases, the enzymes involved in this pathway have been deduced strictly from genome annotations with little direct genetic evidence, such as mutant studies, to confirm
Cuong X. Nguyen +5 more
wiley +1 more source
Encapsulation of sugar beet phytoglobin BvPgb 1.2 and myoglobin in a lipid sponge phase system
Frontiers in Soft Matter, 2023 Globins are usually associated with oxygen carriage in vertebrates. However, plants also contain similar heme-containing proteins, called phytoglobins (Pgbs).
Jennifer Gilbert +7 more
doaj +1 more source
Design of Artificial Enzymes: Insights into Protein Scaffolds
ChemBioChem, Volume 24, Issue 6, March 14, 2023., 2023 The design of artificial enzymes has emerged as a promising tool for the generation of potent biocatalysts able to promote new‐to‐nature reactions. This review aims to give a general overview of suitable protein scaffolds, that could be functionalized with an artificial moiety to develop versatile artificial catalysts. Abstract The design of artificial
Stefanie Hanreich +2 more
wiley +1 more source
Mediators of Inflammation, Volume 2023, Issue 1, 2023., 2023 This review aims at summarizing state‐of‐the‐art knowledge on glycocalyx and SARS‐CoV‐2. The endothelial glycocalyx is a dynamic grid overlying the surface of the endothelial cell (EC) lumen and consists of membrane‐bound proteoglycans and glycoproteins.
Bingxuan Lv +5 more
wiley +1 more source
Factors Controlling the Reactivity of Hydrogen Sulfide with Hemeproteins [PDF]
Biochemistry, 2009 Hemoglobin I (HbI) from the clam Lucina pectinata is an intriguing hemeprotein that binds and transports H(2)S to sulfide-oxidizing chemoautotrophic bacteria to maintain a symbiotic relationship and to protect the mollusk from H(2)S toxicity. Single point mutations at E7, B10, and E11 were introduced into the HbI heme pocket to define the reactivity of
Sebastian Fernandez-Alberti +9 more
openaire +2 more sources
Insights into Sulfhemoglobin Detection: UV‐Vis and Fluorescence Spectroscopy Correlations
Journal of Chemistry, Volume 2023, Issue 1, 2023., 2023 The mechanisms by which drugs and several sulfur chemicals induce sulfhemoglobin formation have not yet been elucidated. However, enzymes producing hydrogen sulfide in mammalian tissues and organs suggest sulfhemoglobin and sulfmyoglobin formation mechanisms are more complex than previously hypothesized. The process involves the interaction of H2S with
Lysmarie Santos-Velázquez +2 more
wiley +1 more source