Results 81 to 90 of about 6,457,465 (175)

Structural Insights into Clostridium perfringens Delta Toxin Pore Formation.

PLoS ONE, 2013
Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
Jessica Huyet, Claire E Naylor, Christos G Savva, Maryse Gibert, Michel R Popoff, Ajit K Basak   +5 more
doaj   +1 more source

Antibiotic Resistance and Pathogenicity of Vibrio Species in Aquaculture: Implications for Fish Health and Food Safety in LMICs

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Pathogenic Vibrio species isolated from aquaculture environments in low‐ and middle‐income countries exhibit elevated antimicrobial resistance and multiple virulence traits. These findings highlight significant risks to fish health and food safety, underscoring the need for strengthened antimicrobial stewardship, robust biosecurity measures and ...
Asiphe Hobe, Luyanda Msolo, Kingsley Ehi Ebomah, Ishmael Festus Jaja, James Wabwire Oguttu, Anthony Ifeanyi Okoh   +5 more
wiley   +1 more source

E. coli alpha-hemolysin: a membrane-active protein toxin.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1999
alpha-Hemolysin is synthesized as a 1024-amino acid polypeptide, then intracellularly activated by specific fatty acylation. A second activation step takes place in the extracellular medium through binding of Ca2+ ions. Even in the absence of fatty acids and Ca2+ HlyA is an amphipathic protein, with a tendency to self-aggregation.
F M, Goñi, H, Ostolaza
openaire   +1 more source

Distribution and dynamics of epidemic and pandemic Vibrio parahaemolyticus virulence factors

Frontiers in Cellular and Infection Microbiology, 2013
Vibrio parahaemolyticus, autochthonous to estuarine, marine, and coastal environments throughout the world, is the causative agent of food-borne gastroenteritis.
Daniela eCeccarelli, Nur A Hasan, Nur A Hasan, Anwar eHuq, Anwar eHuq, Rita R Colwell, Rita R Colwell, Rita R Colwell, Rita R Colwell   +8 more
doaj   +1 more source

Dysbiosis in the Pathogenesis of Atopic Dermatitis

The Journal of Dermatology, Volume 53, Issue 3, Page 388-398, March 2026.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction and immune dysregulation. Recent research highlights cutaneous dysbiosis as a critical factor in its pathogenesis. In this review, we summarize the interplay between the skin microbiota and host immunity, contrasting the homeostatic ...
Hiroki Okamoto, Yuumi Nakamura
wiley   +1 more source

Mycobacterial tlyA gene product is localized to cell-wall without signal sequence.

Frontiers in Cellular and Infection Microbiology, 2015
The mycobacterial tlyA gene product, Rv1694 (MtbTlyA), has been annotated as 'hemolysin' which was re-annotated as 2'-O rRNA methyl transferase. In order to function as a hemolysin, it must reach extracellular milieu with the help of signal sequence(s ...
Santosh eKumar, Ekansh eMittal, Sapna eDeore, Anil eKumar, Aejazur eRahman, Krishnasastry V Musti   +5 more
doaj   +1 more source

Analysis of Human miRNA Derived From Bladder Epithelial Cells Infected With Uropathogenic Escherichia coli

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT MicroRNAs (miRNAs) have been shown to regulate many cellular processes and to play a role in host‐pathogen interactions. However, the role of miRNA in urinary tract infection (UTI) remains unclear. The aim of this study was to analyze and compare miRNAs from supernatants of human bladder epithelial cells infected with ESBL‐producing (ESBL019 ...
Katarina Persson, Isak Demirel, Ignacio Rangel, Robert Kruse   +3 more
wiley   +1 more source

The fc fragment of IgMs binds C1q to activate the first step of the classical complement pathway, while inhibiting complement‐dependent cytotoxicity

The FEBS Journal, Volume 293, Issue 5, Page 1358-1375, March 2026.
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto, Anne Chouquet, Isabelle Bally, Véronique Rossi, Nicole M. Thielens, Chantal Dumestre‐Pérard, Renate Kunert, Christine Gaboriaud, Wai Li Ling, Jean‐Baptiste Reiser   +9 more
wiley   +1 more source

How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
wiley   +1 more source

E. coli a-hemolysin: a membrane-active protein toxin

Brazilian Journal of Medical and Biological Research, 1998
Alpha-Hemolysin is synthesized as a 1024-amino acid polypeptide, then intracellularly activated by specific fatty acylation. A second activation step takes place in the extracellular medium through binding of Ca2+ ions. Even in the absence of fatty acids and Ca2+ HlyA is an amphipathic protein, with a tendency to self-aggregation. However, Ca2+-binding
Goñi, F.M., Ostolaza, H.
openaire   +3 more sources