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Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections [PDF]

open access: yesFrontiers in Microbiology, 2020
Hendra virus (HeV) and Cedar virus (CedV) are henipaviruses, which fall into the Paramyxoviridae family of single-stranded, negative-sense RNA viruses. HeV is classified as a Biosafety Level-4 (BSL-4) agent, as it is highly pathogenic and is often fatal ...
Mingyue Chen   +8 more
doaj   +5 more sources

Henipavirus Infections: Lessons from Animal Models [PDF]

open access: yesPathogens, 2013
The Henipavirus genus contains two highly lethal viruses, the Hendra and Nipah viruses and one, recently discovered, apparently nonpathogenic member; Cedar virus.
Kévin P. Dhondt, Branka Horvat
doaj   +6 more sources

Henipavirus in Northern Short-Tailed Shrew, Alabama, USA [PDF]

open access: yesEmerging Infectious Diseases
RNA metagenomic analysis of tissues from 4 wild-caught northern short-tailed shrews in Alabama, USA, revealed a novel henipavirus (family Paramyxoviridae).
Rhys H. Parry   +9 more
doaj   +3 more sources

Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus infection in vivo, we performed experimental infections in ferrets followed by genome-wide gene
Alberto J Leon   +8 more
doaj   +4 more sources

Trafficking and Activation of Henipavirus, Parahenipavirus, and Henipa-like Virus Fusion Proteins [PDF]

open access: yesViruses
Henipaviruses are emerging zoonotic viruses that have caused deadly outbreaks in humans and livestock across several regions of the world. The fusion (F) protein of henipaviruses plays a critical role in viral entry into host cells and represents a key ...
Chanakha K. Navaratnarajah   +1 more
doaj   +2 more sources

Genetic Diversity and Geographic Spread of Henipaviruses [PDF]

open access: yesEmerging Infectious Diseases
Henipaviruses, such as Hendra and Nipah viruses, are major zoonotic pathogens that cause encephalitis and respiratory infections in humans and animals.
Yakhouba Kane   +8 more
doaj   +2 more sources

Serological and molecular analysis of henipavirus infections in synanthropic fruit bat and rodent populations in the Centre and North regions of Cameroon (2018–2020) [PDF]

open access: yesBMC Veterinary Research
Background Bats and rodents have been identified as reservoirs for several highly pathogenic and zoonotic viruses including henipaviruses, a genus within the Paramyxoviridae family.
Cyrille Mbanwi Mbu’u   +11 more
doaj   +2 more sources

Characterization of an mRNA-Encoded Antibody Against Henipavirus [PDF]

open access: yesCurrent Issues in Molecular Biology
Nipah and Hendra viruses are lethal zoonotic pathogens with no approved vaccines or therapeutics. mRNA produced via in vitro transcription enables endogenous protein expression and cost reduction.
Zixuan Liu   +9 more
doaj   +2 more sources

Nipah: The Jumping Virus [PDF]

open access: yesNational Journal of Laboratory Medicine, 2020
Nipah virus (NiV), infection is an emerging zoonosis with a high mortality rate, and severe neurological and respiratory involvement in humans. NiV, a Paramyxovirus belonging to the genus Henipavirus is highly pathogenic and has a mortality rate which ...
Anuradha Sharma, Anupriya Wadhwa
doaj   +1 more source

Nipah: An Interesting stance [PDF]

open access: yesHealth Promotion Perspectives, 2020
Nipah instead was one of the most fatal outbreaks of diseases in the mankind which was initially assumed as Japanese encephalitis. A multidisciplinary exploration was done at several levels of microbiology, histopathology and genetics which led to the ...
Ruchi D. Raval, Mansi Mehta
doaj   +1 more source

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