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The Immunobiology of Nipah Virus
Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that emerged in Malaysia in 1998. It is a human pathogen capable of causing severe respiratory infection and encephalitis. The natural reservoir of NiV, Pteropus fruit bats, remains a continuous
Yvonne Jing Mei Liew +9 more
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IntroductionNipah virus (NiV) and Hendra virus (HeV), of the genus Henipavirus, family Paramyxoviridae, are classified as Risk Group 4 (RG4) pathogens that cause respiratory disease in pigs and acute/febrile encephalitis in humans with high mortality ...
Wenjun Zhu +13 more
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Paramyxoviruses, negative-sense single-stranded RNA viruses, pose a critical threat to human public health. Currently, 78 species, 17 genera, and 4 subfamilies of paramyxoviruses are harbored by multiple natural reservoirs, including rodents, bats, birds,
Seung-Ho Lee +16 more
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Development of a Porcine Cell Line Stably Expressing Ephrin-B2 for Nipah Virus Research and Diagnostic Testing. [PDF]
ABSTRACT Nipah virus (NiV) is a highly pathogenic zoonotic virus transmitted from bats to humans through pigs as a crucial intermediate host. NiV outbreaks pose significant public health and economic threats, especially for pig farmers. Although the World Organization for Animal Health recommends African green monkey‐derived Vero cells for NiV ...
Zhang H, Saito A.
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Pathology of Acute Henipavirus Infection in Humans and Animals [PDF]
Zoonoses as causes of human infections have been increasingly reported, and many of these are viruses that cause central nervous system infections. This paper focuses on the henipaviruses (family Paramyxoviridae, genushenipavirus) that have recently emerged to cause severe encephalitis and systemic infection in humans and animals in the Asia-Pacific ...
Wong, K. T., Ong, K. C.
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Evolution of Nipah Virus Infection: Past, Present, and Future Considerations
Nipah virus (NiV) is a zoonotic paramyxovirus of the Henipavirus genus first identified in Malaysia in 1998. Henipaviruses have bat reservoir hosts and have been isolated from fruit bats found across Oceania, Asia, and Africa.
Naomi Hauser +4 more
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Outbreak of Henipavirus Infection, Philippines, 2014
En 2014, l'infection à henipavirus a causé une maladie grave chez les humains et les chevaux dans le sud des Philippines ; les taux de mortalité chez les humains étaient élevés. Une transmission de cheval à humain et d'humain à humain s'est produite. La source la plus probable d'infection des chevaux était les chauves-souris frugivores.
Paola Katrina Ching +16 more
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Nipah and Hendra viruses are deadly zoonotic paramyxoviruses with a case fatality rate of upto 75%. The viruses belong to the genus henipavirus in the family Paramyxoviridae, a family of negative-sense single-stranded RNA viruses.
Sabahat Gazal +7 more
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Reprogrammed Pteropus Bat Stem Cells as A Model to Study Host-Pathogen Interaction during Henipavirus Infection [PDF]
Bats are natural hosts for numerous zoonotic viruses, including henipaviruses, which are highly pathogenic for humans, livestock, and other mammals but do not induce clinical disease in bats. Pteropus bats are identified as a reservoir of henipaviruses and the source of transmission of the infection to humans over the past 20 years.
Aurine, Noémie +8 more
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Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses
Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1 pandemic of 2009).
Brent Brown +7 more
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