Results 41 to 50 of about 3,651 (163)

Protection Against Henipavirus Infection by Use of Recombinant Adeno-Associated Virus–Vector Vaccines [PDF]

The Journal of Infectious Diseases, 2012
Nipah virus (NiV) and Hendra virus (HeV) are closely related, recently emerged paramyxoviruses that are capable of causing considerable morbidity and mortality in several mammalian species, including humans. Henipavirus-specific vaccines are still commercially unavailable, and development of novel antiviral strategies to prevent lethal infections due ...
Ploquin, Aurélie, Szécsi, Judit, Mathieu, Cyrille, Guillaume, Vanessa, Barateau, Véronique, Ong, Kien Chai, Wong, Kum Thong, François-Loïc, Cosset, Horvat, Branka, Salvetti, Anna   +9 more
openaire   +3 more sources

Henipavirus Immune Evasion and Pathogenesis Mechanisms: Lessons Learnt from Natural Infection and Animal Models

Viruses, 2022
Nipah henipavirus (NiV) and Hendra henipavirus (HeV) are zoonotic emerging paramyxoviruses causing severe disease outbreaks in humans and livestock, mostly in Australia, India, Malaysia, Singapore and Bangladesh. Both are bat-borne viruses and in humans, their mortality rates can reach 60% in the case of HeV and 92% for NiV, thus being two of the ...
Philip Lawrence, Beatriz Escudero-Pérez
openaire   +3 more sources

Clinical Outcome of Henipavirus Infection in Hamsters Is Determined by the Route and Dose of Infection [PDF]

Journal of Virology, 2011
ABSTRACTNipah virus (NiV) and Hendra virus (HeV) are emerging zoonotic viruses and the causative agents of severe respiratory disease and encephalitis in humans. Little is known about the mechanisms that govern the development of respiratory and neurological disease.
Barry, Rockx, Douglas, Brining, Joshua, Kramer, Julie, Callison, Hideki, Ebihara, Keith, Mansfield, Heinz, Feldmann   +6 more
openaire   +2 more sources

Henipavirus Infections - An Expanding Zoonosis from Fruit Bats

Journal of Disaster Research, 2011
The henipavirus genus has two members – the Hendra virus (HeV) and the Nipah virus (NiV). HeV and NiV, identified in the 1990s as a paramyxovirus, cause fatalities in humans and animals. They are now classified as biosafety level 4 pathogens. HeV caused fatal respiratory infection in horses and humans in Australia in 1994, in which 2 persons died.
Chieko Kai, Misako Yoneda
openaire   +1 more source

Nipah Virus Disease: Epidemiological, Clinical, Diagnostic and Legislative Aspects of This Unpredictable Emerging Zoonosis

Animals, 2022
Nipah virus (NiV) infection is a viral disease caused by a Henipavirus, belonging to the Paramyxoviridae family, responsible for a zoonosis. The course of the disease can be very serious and lead to death.
Luigi Bruno, Maria Anna Nappo, Luca Ferrari, Rosanna Di Lecce, Chiara Guarnieri, Anna Maria Cantoni, Attilio Corradi   +6 more
doaj   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Integrating host condition into spatiotemporal multiscale models improves virus shedding predictions

Ecography, Volume 2025, Issue 9, September 2025.
Understanding where and when pathogens occur in the environment has implications for reservoir population health and infection risk. In reservoir hosts, infection status and pathogen shedding are affected by processes interacting across different scales: from landscape features affecting host location and transmission to within‐host processes affecting
Andrew M. Kramer, Christina L. Faust, Adrian A. Castellanos, Ilya R. Fischhoff, Alison J. Peel, Peggy Eby, Manuel Ruiz‐Aravena, Benny Borremans, Raina K. Plowright, Barbara A. Han   +9 more
wiley   +1 more source

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. [PDF]

PLoS Pathogens, 2016
For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system.
Preeti Bharaj, Yao E Wang, Brian E Dawes, Tatyana E Yun, Arnold Park, Benjamin Yen, Christopher F Basler, Alexander N Freiberg, Benhur Lee, Ricardo Rajsbaum   +9 more
doaj   +1 more source

Henipavirus neutralising antibodies in an isolated island population of African fruit bats. [PDF]

PLoS ONE, 2012
Isolated islands provide valuable opportunities to study the persistence of viruses in wildlife populations, including population size thresholds such as the critical community size.
Alison J Peel, Kate S Baker, Gary Crameri, Jennifer A Barr, David T S Hayman, Edward Wright, Christopher C Broder, Andrés Fernández-Loras, Anthony R Fooks, Lin-Fa Wang, Andrew A Cunningham, James L N Wood   +11 more
doaj   +1 more source

Mapping the Potential Risk of Coronavirus Spillovers in a Global Hotspot

Global Change Biology, Volume 31, Issue 9, September 2025.
Bats host a vast array of viruses, including those behind SARS and COVID‐19. This study maps coronavirus spillover risk hotspots across South and Southeast Asia by combining horseshoe bat species distributions, forest fragmentation, and human population density.
R. Sedricke Lapuz, Ada Chornelia, Alice C. Hughes   +2 more
wiley   +1 more source