Results 61 to 70 of about 3,651 (163)

Interferon Production and Signaling Pathways Are Antagonized during Henipavirus Infection of Fruit Bat Cell Lines

PLoS ONE, 2011
Bats are natural reservoirs for a spectrum of infectious zoonotic diseases including the recently emerged henipaviruses (Hendra and Nipah viruses). Henipaviruses have been observed both naturally and experimentally to cause serious and often fatal disease in many different mammal species, including humans.
Virtue E.R., Marsh G.A., Baker M.L., Wang L.-F.   +3 more
openaire   +6 more sources

In silico Drug Discovery of Novel Small Lead Compounds Targeting Nipah Virus Attachment Glycoprotein

Journal of Integrated Health Sciences, 2018
Introduction: Nipah virus (NiV) and Hendra virus are the type species of the highly pathogenic paramyxovirus genus Henipavirus, which can cause severe respiratory disease and fatal encephalitis infections in humans.
Ashish P. Shah, Bhumika M. Parmar, Mubasarin A. Ghodawala, Avinashkumar Seth   +3 more
doaj   +1 more source

Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N‐ and C‐terminal constituent domains

The FEBS Journal, Volume 292, Issue 3, Page 556-581, February 2025.
The W proteins of Nipah and Hendra viruses exhibit fibrillation abilities in vitro, which have been attributed to the intrinsically disordered N‐terminal domain (NTD). Our research shows that the C‐terminal domain (CTD) of both viruses is intrinsically disordered and non‐fibrillogenic.
Giulia Pesce, Frank Gondelaud, Denis Ptchelkine, Christophe Bignon, Patrick Fourquet, Sonia Longhi   +5 more
wiley   +1 more source

Influence of Host and Landscape‐Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals

Veterinary Medicine and Science, Volume 11, Issue 1, January 2025.
The figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
María del Carmen Villalobos‐Segura, Oscar Rico‐Chávez, Gerardo Suzán, Andrea Chaves   +3 more
wiley   +1 more source

Chiroptera as a Potential Reservoir of Dangerous for Humans Viruses in the territory of the Republic of Guinea. Part 1

Проблемы особо опасных инфекций, 2018
Chiroptera is one of the largest in numbers orders of mammals which can take on the role of natural host and vector of various viruses, bacteria, and pathogenic fungi.
A. M. Porshakov, Yu. V. Kononova, V. B. Loktev, M. I. Boiro   +3 more
doaj   +1 more source

In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against Brucella canis Using a Reverse Vaccinology Approach

Journal of Immunology Research, Volume 2025, Issue 1, 2025.
Brucella canis is a Gram‐negative bacterium that causes canine brucellosis, a zoonotic disease with serious implications for public health and the global economy. Currently, there is no effective preventive vaccine for B. canis. Control measures include diagnostic testing, isolation, and euthanasia of infected animals.
Vicente Arriagada, Alberto Osorio, Crisleri Carrera-Naipil, Carlos A. Villacis-Aguirre, Cristian Escobar, Nicolás Morales, Danthe Villa, Lien Mardones, Dafne Pérez, Macarena Jara, Raúl E. Molina, Ítalo Ferrari, Sebastián Azocar, Leonardo A. Gómez, Ángel A. Oñate, Baohui Xu   +15 more
wiley   +1 more source

Emergence of a Novel Canine Distemper Virus Variant in Urbanized Free‐Ranging Marmosets (Callithrix penicillata)

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
The black‐tufted marmoset (Callithrix penicillata), commonly found in urban areas of Central Brazil, is vulnerable to pathogen spillover from domestic animals and humans. Here, we report an outbreak of natural canine distemper virus (CDV) infection among urbanized free‐ranging black‐tufted marmosets.
Tais Meziara Wilson, Davi Emanuel Ribeiro de Sousa, Isabel L. Macêdo, Mizael Machado, Gabriela Rodrigues de Toledo Costa, Pamela Fair, Jana M. Ritter, Hannah A. Bullock, Marlene DeLeon-Carnes, Elizabeth Lee, Pedro Henrique de Oliveira Passos, Daniel Garkauskas Ramos, Alessandro Pecego Martins Romano, Sandro Patroca da Silva, Livia Medeiros Nevs Casseb, Livia Caricio Martins, Luis Janssen Maia, Bergmann Morais Ribeiro, Eduardo Mauricio Mendes de Lima, Cristiano Barros de Melo, Márcio Botelho de Castro, Fabian Lean   +21 more
wiley   +1 more source

Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Vietnam is a wildlife trade hotspot presenting multiple high‐risk interfaces for pathogen spillover from wildlife to humans. However, the zoonotic disease risk remains poorly characterized in the country and needs to be assessed to better inform policy dialog and legislative reforms.
Alice Latinne, Pawin Padungtod, Fedor Korennoy   +2 more
wiley   +1 more source

Multi-platform omics analysis of Nipah virus infection reveals viral glycoprotein modulation of mitochondria

Cell Reports
Summary: The recent global pandemic illustrates the importance of understanding the host cellular infection processes of emerging zoonotic viruses. Nipah virus (NiV) is a deadly zoonotic biosafety level 4 encephalitic and respiratory paramyxovirus.
Gunner P. Johnston, Fikret Aydemir, Haewon Byun, Emmie de Wit, Kristie L. Oxford, Jennifer E. Kyle, Jason E. McDermott, Brooke L. Deatherage Kaiser, Cameron P. Casey, Karl K. Weitz, Heather M. Olson, Kelly G. Stratton, Natalie C. Heller, Viraj Upadhye, I. Abrrey Monreal, J. Lizbeth Reyes Zamora, Lei Wu, D.H. Goodall, David W. Buchholz, Joeva J. Barrow, Katrina M. Waters, Ruth N. Collins, Heinz Feldmann, Joshua N. Adkins, Hector C. Aguilar   +24 more
doaj   +1 more source

Bat‐Borne RNA Viruses: Addressing the Rising Health Risks in Bangladesh

Public Health Challenges, Volume 4, Issue 2, June 2025.
Md Nasir Ahmed
wiley   +1 more source