Results 71 to 80 of about 3,651 (163)

Risk Evaluation and Mitigation Strategies for Potential Outbreaks of Nipah Virus Infection: Evidenced by the Recent Incidences in Southeast Asian Countries

open access: yesHealth Science Reports, Volume 7, Issue 12, December 2024.
ABSTRACT Background The importance of studying Nipah virus (NiV) stems from its high fatality rates and potential for causing widespread outbreaks. Recent incidences in Southeast Asian countries highlight the urgent need for effective risk evaluation and mitigation strategies.
Md. Ashrafur Rahman   +9 more
wiley   +1 more source

A highly effective ferritin-based divalent nanoparticle vaccine shields Syrian hamsters against lethal Nipah virus

open access: yesFrontiers in Immunology
The Nipah virus (NiV), a highly deadly bat-borne paramyxovirus, poses a substantial threat due to recurrent outbreaks in specific regions, causing severe respiratory and neurological diseases with high morbidity. Two distinct strains, NiV-Malaysia (NiV-M)
Chunhong Yin   +29 more
doaj   +1 more source

A Functional Genomics Approach to Henipavirus Research: The Role of Nuclear Proteins, MicroRNAs and Immune Regulators in Infection and Disease [PDF]

open access: yes, 2017
Hendra and Nipah viruses (family Paramyxoviridae, genus Henipavirus) are zoonotic RNA viruses that cause lethal disease in humans and are designated as Biosafety Level 4 (BSL4) agents. Moreover, henipaviruses belong to the same group of viruses that cause disease more commonly in humans such as measles, mumps and respiratory syncytial virus. Due to the
Stewart, CR   +4 more
openaire   +3 more sources

Unravelling the mystery of Nipah virus: from virus to therapeutics: current insights and future frontiers

open access: yesBulletin of the National Research Centre
Background Nipah virus (NiV) is a high-risk zoonotic infection that results in severe respiratory and neurological disease, with case fatality rates typically exceeding 70%. Driven by reservoir-host spillover and intermittent human-to-human transmission,
Jignesh Bhate   +2 more
doaj   +1 more source

Novel transcription and replication-competent virus-like particles system modelling the Nipah virus life cycle

open access: yesEmerging Microbes and Infections
Nipah virus (NiV), a highly pathogenic Henipavirus in humans, has been responsible for annual outbreaks in recent years. Experiments involving live NiV are highly restricted to biosafety level 4 (BSL-4) laboratories, which impedes NiV research.
Yulong Wang   +14 more
doaj   +1 more source

Inhibition of henipavirus infection by Nipah virus attachment glycoprotein occurs without cell-surface downregulation of ephrin-B2 or ephrin-B3

open access: yesJournal of General Virology, 2007
Nipah virus (NiV) and Hendra virus (HeV) are newly identified members of the family Paramyxoviridae and have been classified in the new genus Henipavirus based on unique genetic characteristics distinct from other paramyxoviruses.
Bevan, Sawatsky   +4 more
openaire   +2 more sources

Predicting the next pandemic: VACCELERATE ranking of the World Health Organization's Blueprint for Action to Prevent Epidemics

open access: yesTravel Medicine and Infectious Disease
Introduction: The World Health Organization (WHO)'s Research and Development (R&D) Blueprint for Action to Prevent Epidemics, a plan of action, highlighted several infectious diseases as crucial targets for prevention.
Jon Salmanton-García   +127 more
doaj   +1 more source

Abdominal Pain in Langya Henipavirus and Severity of Infection

open access: yesAssam Journal of Internal Medicine, 2023
Pathum Sookaromdee, Viroj Wiwanitkit
openaire   +3 more sources

Development of a real-time RT-PCR assay for detection of Hendra and Nipah viruses

open access: yesИнфекция и иммунитет
The article is devoted to the development of a method for detection of viral RNA of two highly pathogenic zoonotic viruses from the genus Henipavirus — Hendra and Nipah using real-time reverse transcription polymerase chain reaction.
Svetlana A. Shirobokova   +5 more
doaj   +1 more source

An in vivo BSL-2 model for henipavirus infection based on bioluminescence imaging of recombinant Cedar virus replication in mice

open access: yesFrontiers in Chemical Biology
Henipaviruses are enveloped single-stranded, negative-sense RNA viruses of the paramyxovirus family. Two henipaviruses, Nipah virus and Hendra virus, cause a systemic respiratory and/or neurological disease in humans and ten additional species of mammals, with a high fatality rate. Because of their highly pathogenic nature, Nipah virus and Hendra virus
Celeste, Huaman   +9 more
openaire   +2 more sources

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