From Theory to Practice: Which Biomarkers Are Ready for Predicting Response in Advanced HCC?
ABSTRACT Systemic therapies for advanced hepatocellular carcinoma (HCC) have expanded considerably with the advent of tyrosine kinase inhibitors, immune checkpoint inhibitors and immunotherapy–anti‐angiogenic combinations. However, despite this therapeutic diversification, first‐line treatment selection remains largely empirical, as few biomarkers are ...
Marie Decraecker +3 more
wiley +1 more source
Abstract The cross‐sectional Master Athletic Laboratory Study of Intramuscular Connective Tissue (MALICoT, DRKS00015764) examined effects of athletic exercise and age on endomysium content in human soleus muscle. Forty‐three clinically healthy male participants were grouped into young (20–35 years) nonphysically active controls (n = 12), young power ...
Christoph S. Clemen +6 more
wiley +1 more source
Epithelial Heparan Sulfate Promotes <i>Staphylococcus aureus</i> Corneal Infection by Inhibiting Cathelicidins. [PDF]
Hayashida K +5 more
europepmc +1 more source
Abstract The endothelial glycocalyx (eGC) is a protein‐rich, hairlike structure covering the luminal surface of endothelial cells, vital for vascular health. Aging and cardiovascular disease (CVD) can compromise eGC integrity, potentially preceding conventional indicators of vascular dysfunction such as reduced endothelium‐dependent vasodilation and ...
Mounica Ayyalasomayajula +5 more
wiley +1 more source
Synthesis of Heparan Sulfate Hexadecasaccharides and Their Molecular Interaction with Mycobacterial Heparin-Binding Hemagglutinin for the Detection of <i>Mycobacterium tuberculosis</i>. [PDF]
Maiti K +13 more
europepmc +1 more source
Structure-guided engineering of prototype foamy virus Env identifies key residues for heparan sulfate binding and enhances transduction efficiency. [PDF]
Shin HS +8 more
europepmc +1 more source
Applications of Surface Plasmon Resonance in Heparan Sulfate Interactome Research. [PDF]
Datta P, Dordick JS, Zhang F.
europepmc +1 more source
A Novel Chimeric Molecule of Heparanase and Ig-Fc Enables Histochemical and Cytochemical Detection of O-sulfated Heparan Sulfate. [PDF]
Shi J +18 more
europepmc +1 more source
The Role of the Cell Surface Heparan Sulfate Proteoglycan Syndecan-3 in Breast Cancer Pathophysiology. [PDF]
Habenicht L +7 more
europepmc +1 more source

