Results 211 to 220 of about 79,508 (247)
Some of the next articles are maybe not open access.
Heparan Sulfate Proteoglycans in Diabetes
Seminars in Thrombosis and Hemostasis, 2021AbstractDiabetes is a complex disorder responsible for the mortality and morbidity of millions of individuals worldwide. Although many approaches have been used to understand and treat diabetes, the role of proteoglycans, in particular heparan sulfate proteoglycans (HSPGs), has only recently received attention.
openaire +2 more sources
1999
Abstract Heparan sulfate proteoglycans (HSPGs)1 are highly charged macromolecules consisting of different core proteins with covalently linked heparan sulfate chains (HS) of varying monosaccharide sequence. These molecules are involved in a multitude of biologic processes including regulation of mesoderm induction, extension of neurites,
Nicholas W Shworak, Robert D Rosenberg
openaire +1 more source
Abstract Heparan sulfate proteoglycans (HSPGs)1 are highly charged macromolecules consisting of different core proteins with covalently linked heparan sulfate chains (HS) of varying monosaccharide sequence. These molecules are involved in a multitude of biologic processes including regulation of mesoderm induction, extension of neurites,
Nicholas W Shworak, Robert D Rosenberg
openaire +1 more source
Antithrombin, heparin, and heparan sulfate
Critical Care Medicine, 2002To review the experimental and clinical evidence that antithrombin has multiple mechanisms for both its anticoagulant and anti-inflammatory properties. The interaction between antithrombin and specific polysulfated, acidic oligosaccharide moieties found on heparin and related proteoglycan molecules within the circulation and on endothelial surfaces ...
Steven M, Opal +3 more
openaire +2 more sources
Biological Activities of Heparan Sulfate
2014Heparan sulfate was isolated from two bivalve mollusks such as Tridacna maxima and Perna viridis. The isolated heparin was quantified in crude as well as purified samples and they were estimated as 2.72 and 2.2g/kg (crude) and 260 and 248 mg/g (purified) in T. maxima and P. viridis, respectively.
Muthuvel, Arumugam, Sadhasivam, Giji
openaire +2 more sources
Heparan Sulfate Proteoglycans in Amyloidosis
2010Amyloidosis is a generic term for a group of diseases characterized by deposits in different organ systems of insoluble materials composed mainly of distinct fibrillar proteins named amyloid. Besides amyloid, heparan sulfate proteoglycan (HSPG), is commonly found in most amyloid deposits, suggesting that HS/HSPG may be functionally involved in the ...
Xiao, Zhang, Jin-Ping, Li
openaire +2 more sources
Heparan sulfate-growth factor interactions
2002Publisher Summary This chapter examines the techniques that are typically used to demonstrate the dependence of receptor–growth factor interactions on heparan sulfate (HS), focusing on the fibroblast growth factors (FGFs). It describe methods for blocking the binding of growth factor to cell surface HS, and a novel method in which FGF and a soluble ...
openaire +2 more sources
Integral membrane heparan sulfate proteoglycans
The FASEB Journal, 1993Heparan sulfate is a regulatory polysaccharide. It modulates specific growth factor‐receptor interactions, accelerates the formation of specific proteinase‐proteinase inhibitor complexes, and mediates interactions of the cell surface with several enzymes and structural proteins.
openaire +2 more sources
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans
Nature, 2021Dimitrios Tsiantoulas +2 more
exaly
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Cell, 2020Thomas Mandel Clausen +2 more
exaly