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Tinkering with heparan sulfate sulfation to steer development
Trends in Cell Biology, 2007Heparan sulfate (HS) proteoglycans, at the cell surface and extracellular matrix, facilitate ligand-receptor interactions crucial to many physiological processes. The distinct sulfation patterns of HS sugar chains presented by their protein core are key to HS proteoglycan activity. Tight regulation of several Golgi complex enzyme families is crucial to
Gorsi, Bushra, Stringer, Sally E.
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The anticoagulant effect of heparan sulfate and dermatan sulfate
Thrombosis Research, 1976Abstract The potency of the various glycosaminoglycans (GAGs) as anticoagulants in the activated partial thromboplastin time (APTT) test system has been investigated. Heparin, heparan sulfate (HS) and dermatan sulfate (DS) exhibit anticoagulant effect.
A N, Teien, U, Abildgaard, M, Höök
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Heparan Sulfate Proteoglycans in Amyloidosis
2010Amyloidosis is a generic term for a group of diseases characterized by deposits in different organ systems of insoluble materials composed mainly of distinct fibrillar proteins named amyloid. Besides amyloid, heparan sulfate proteoglycan (HSPG), is commonly found in most amyloid deposits, suggesting that HS/HSPG may be functionally involved in the ...
Xiao, Zhang, Jin-Ping, Li
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Emerging chemical and biochemical tools for studying 3-O-sulfated heparan sulfate
American Journal of Physiology - Cell Physiology, 2022Lars C Pedersen
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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Cell, 2020Thomas Mandel Clausen +2 more
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Structure of Heparan Sulfate and Dermatan Sulfate
Annals of the New York Academy of Sciences, 1989openaire +2 more sources
3‐O‐Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake
Angewandte Chemie - International Edition, 2020Xuehong Song, Guowei Su, Xinyue Liu
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