Results 61 to 70 of about 250,900 (178)

Congenital Disorders of Deficiency in Glycosaminoglycan Biosynthesis

Frontiers in Genetics, 2021
Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, and heparan sulfate are covalently attached to specific core proteins to form proteoglycans, which are distributed at the cell surface as well as in the extracellular matrix ...
Shuji Mizumoto, Shuhei Yamada
doaj   +1 more source

Clinicoepidemiologic Profile of Oral Kaposi Sarcoma in People Living With HIV: A Systematic Review and Meta‐Analysis

Head &Neck, EarlyView.
ABSTRACT Background To characterize the clinicoepidemiologic profile of HIV‐associated oral Kaposi sarcoma (OKS) and quantitatively synthesize its frequency, anatomical distribution, and temporal patterns across antiretroviral therapy (ART) eras. Methods Six databases and gray literature were searched.
Ericles Otávio, Rebeca Ferreira Badaró, Daniel Pignatari Mahet Rodrigues, Giselle de Medeiros Silva, José Alcides Almeida de Arruda, Victor Zanetti Drumond, Jefferson R. Tenório, Lucas Alves Jural, Marcela Baraúna Magno, Lucianne Cople Maia, Bruno Augusto Benevenuto de Andrade   +10 more
wiley   +1 more source

Immunopurification and characterization of a neuronal heparan sulfate proteoglycan [PDF]

, 1985
We have identified a unique heparan sulfate (HeS) proteoglycan synthesized by the neuronal-like cell line PC12. The proteoglycan, purified with monoclonal antibodies from medium conditioned by PC12 cells, has an apparent molecular weight of 350,000, and ...
RJ Greenspan, Greenspan, RJ, WD Matthew, AD Lander, Reichardt, LF, Matthew, WD, LF Reichardt, Lander, AD   +7 more
core   +1 more source

Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors

Cell Reports, 2018
Summary: Establishing synaptic contacts between neurons is paramount for nervous system function. This process involves transsynaptic interactions between a host of cell adhesion molecules that act in cooperation with the proteins of the extracellular ...
Cesare Orlandi, Yoshihiro Omori, Yuchen Wang, Yan Cao, Akiko Ueno, Michel J. Roux, Giuseppe Condomitti, Joris de Wit, Motoi Kanagawa, Takahisa Furukawa, Kirill A. Martemyanov   +10 more
doaj   +1 more source

The Extracellular and Cytoplasmic Domains of Syndecan Cooperate Postsynaptically to Promote Synapse Growth at the Drosophila Neuromuscular Junction. [PDF]

PLoS ONE, 2016
The heparan sulfate proteoglycan (HSPG) Syndecan (Sdc) is a crucial regulator of synapse development and growth in both vertebrates and invertebrates. In Drosophila, Sdc binds via its extracellular heparan sulfate (HS) sidechains to the receptor protein ...
Margaret U Nguyen, Jereen Kwong, Julia Chang, Victoria G Gillet, Rachel M Lee, Karl Gregory Johnson   +5 more
doaj   +1 more source

Collagens and proteoglycans of the corneal extracellular matrix

Brazilian Journal of Medical and Biological Research, 2003
The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with ...
Y.M. Michelacci
doaj   +1 more source

Syndecan 4 Upregulation on Activated Langerhans Cells Counteracts Langerin Restriction to Facilitate Hepatitis C Virus Transmission

Frontiers in Immunology, 2020
Sexually transmitted Hepatitis C virus (HCV) infections and high reinfections are a major concern amongst men who have sex with men (MSM) living with HIV-1 and HIV-negative MSM.
Bernadien M. Nijmeijer, Julia Eder, Catharina J. M. Langedijk, Tanja M. Kaptein, Sofie Meeussen, Pascale Zimmermann, Pascale Zimmermann, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek   +8 more
doaj   +1 more source

Ultraviolet irradiation induces the accumulation of chondroitin sulfate, but not other glycosaminoglycans, in human skin. [PDF]

PLoS ONE, 2011
Ultraviolet (UV) light alters cutaneous structure and function. Prior work has shown loss of dermal hyaluronan after UV-irradiation of human skin, yet UV exposure increases total glycosaminoglycan (GAG) content in mouse models.
Benjamin Boegel Werth, Muhammad Bashir, Laura Chang, Victoria P Werth   +3 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Heparan sulfate proteoglycan as a plasma membrane carrier

, 2003
The plasma membrane defines the border of living cells and provides a barrier to extracellular components. Advances in molecular biology have resulted in the development of novel therapeutic strategies (e.g.
Belting, Mattias, Belting, Mattias,, Lund University.   +2 more
core   +1 more source