Results 111 to 120 of about 20,897 (221)

Small Extracellular Vesicles From Radioresistant H3K27M‐Pediatric Diffuse Midline Glioma Cells Modulate Tumor Phenotypes and Radiation Response

Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
Radioresistant H3K27M‐pediatric diffuse midline glioma‐derived extracellular vesicles enhance DNA repair and trigger metabolic and transcriptional changes in radiosensitive tumor cells. These findings reveal vesicle‐mediated intratumoral communication as a driver of intrinsic radioresistance and suggest novel targets to disrupt therapy‐resistant ...
Viral D. Oza, Kenan A. Flores, Yelena Chernyavskaya, Majd A. Al‐Hamaly, Caitlyn B. Smith, Ronald C. Bruntz, Jessica S. Blackburn   +6 more
wiley   +1 more source

Regulation of autophagy, lipid metabolism, and neurodegenerative pathology by heparan sulfate proteoglycans. [PDF]

Front Genet, 2022
Schultheis N, Becker R, Berhanu G, Kapral A, Roseman M, Shah S, Connell A, Selleck S.   +7 more
europepmc   +1 more source

Decoding Glycosylation in Neurodegenerative Diseases: Mechanistic Insights and Therapeutic Opportunities

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Graphical summary of glycosylation impairments in various neurodegenerative disorders. Among the diverse forms of glycosylation, the most extensively studied include N‐glycosylation, O‐glycosylation, and O‐GlcNAcylation. Aberrant glycosylation has been implicated in multiple neurodegenerative conditions.
Haihan Yu, Xing Chen, Yang Yang, Mengke Gu, Kaidi Ren, Ziqing Wei   +5 more
wiley   +1 more source

The Tissue Factor Pathway in Cancer: Overview and Role of Heparan Sulfate Proteoglycans. [PDF]

Cancers (Basel), 2023
Hassan N, Efing J, Kiesel L, Bendas G, Götte M.   +4 more
europepmc   +1 more source

Importance of Heparan Sulfate Proteoglycans in Pancreatic Islets and β-Cells. [PDF]

Int J Mol Sci, 2022
Takahashi I.
europepmc   +1 more source

Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation [PDF]

, 1994
CS Stipp, E. David Litwack, AD Lander
openalex   +1 more source

Bioinformatics analysis identifies heparan sulfate proteoglycans acting as different progress subtypes of biliary atresia. [PDF]

Front Pediatr, 2023
Ding Z, Song W, Zhu W, Xie H, Zhu Z, Tang W.   +5 more
europepmc   +1 more source

The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates. [PDF]

BMC Mol Cell Biol, 2022
Ferreira A, Royaux I, Liu J, Wang Z, Su G, Moechars D, Callewaert N, De Muynck L.   +7 more
europepmc   +1 more source

Influence of Heparan Sulfate Proteoglycans and Factor X on species D Human Adenovirus Uptake and Transduction. [PDF]

Viruses, 2022
Schröer K, Alshawabkeh M, Schellhorn S, Bronder K, Zhang W, Ehrhardt A.   +5 more
europepmc   +1 more source

Cell surface proteoglycan of mammary epithelial cells. Protease releases a heparan sulfate-rich ectodomain from a putative membrane-anchored domain.

, 1985
Alan C. Rapraeger, Merton Bernfield
openalex   +1 more source