Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu +9 more
wiley +1 more source
Heparin inhibition of insulin-like growth factor-binding protein-3 binding to human fibroblasts and rat glioma cells: role of heparan sulfate proteoglycans [PDF]
, 1996 Y. W. Yang
openalex +1 more source
A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani +20 more
wiley +1 more source
The Tissue Factor Pathway in Cancer: Overview and Role of Heparan Sulfate Proteoglycans. [PDF]
Cancers (Basel), 2023 Hassan N +4 more
europepmc +1 more source
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION The PSEN1E280A mutation causes autosomal dominant Alzheimer's disease (ADAD) with predictable onset, enabling presymptomatic studies. Extracellular vesicles (EVs) are emerging biomarkers of cognitive decline, but their role in early ADAD is unclear.
Lina Pineda‐Lopez +14 more
wiley +1 more source
Bioinformatics analysis identifies heparan sulfate proteoglycans acting as different progress subtypes of biliary atresia. [PDF]
Front Pediatr, 2023 Ding Z +5 more
europepmc +1 more source
Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle [PDF]
, 2018 Yuri Yamashita +7 more
openalex +1 more source
Food Science &Nutrition, Volume 14, Issue 1, January 2026.The modified calycosin derivative H10 was more effective in inhibiting cell proliferation through G0/G1 cell cycle arrest, together with inhibiting the migration and colony formation abilities of ovarian cancer cell lines SKOV3 and A2780. Comparative proteomic analysis coupled with Ingenuity Pathway Analysis further delineated calycosin derivative H10 ...
Fuhong Yang +8 more
wiley +1 more source
The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates. [PDF]
BMC Mol Cell Biol, 2022 Ferreira A +7 more
europepmc +1 more source
Post‐Covid Alzheimer and Its Remediation via PROTACs Therapy: A Comprehensive Review
Health Science Reports, Volume 9, Issue 1, January 2026.ABSTRACT Background and Aims Alzheimer's disease (AD) is a progressive neurodegenerative disorder of aging characterized by memory loss and cognitive decline, associated with amyloid‐β toxicity, tau hyperphosphorylation, and neurofibrillary tangle formation. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) affects the central nervous system
Teesta Bhowmick +5 more
wiley +1 more source