Results 81 to 90 of about 11,910 (223)

Tumor size, stage and grade alterations of urinary peptidome in RCC [PDF]

, 2015
Background: Several promising biomarkers have been found for RCC, but none of them has been used in clinical practice for predicting tumour progression.
Bosari, Silvano, Cazzaniga, Marta, Chinello, Clizia, De Sio, Gabriele, Grasso, Angelica, Grasso, Marco, Magni, Fulvio, Mauri, Giancarlo, Rocco, Bernardo Maria Cesare, Signorini, Stefano, Smith, Andrew James, Zoppis, Italo   +11 more
core   +3 more sources

Tumor Cell Migration May Be an Inherent “Foraging” Behavior

Medicine Advances, Volume 4, Issue 1, Page 103-110, March 2026.
Tumor cells gradually form pseudopodia, migrate to necrotic cells, make contact with them, and absorb necrotic cell debris. During this migration, small vesicles formed by dying tumor cells also gradually migrate toward living tumor cells. Once the nutrients from the necrotic cells have been completely absorbed, the living tumor cells will leave ...
Fuqian Zhao, Hongmei Niu, Lusi Zhang, Daofu Shen, Lei Wang   +4 more
wiley   +1 more source

Heparanase Regulates Murine Hair Growth [PDF]

The American Journal of Pathology, 2005
Heparanase is an endoglycosidase that cleaves heparan sulfate, the main polysaccharide component of the extracellular matrix. Heparan sulfate moieties are responsible for the extracellular matrix barrier function, as well as for sequestration of heparin-binding growth factors in the extracellular matrix.
Eyal, Zcharia, Deborah, Philp, Evgeny, Edovitsky, Helena, Aingorn, Shula, Metzger, Hynda K, Kleinman, Israel, Vlodavsky, Michael, Elkin   +7 more
openaire   +2 more sources

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]

, 2018
Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C., Bowler, Nicholas, Craig Hooper, D., Dutta, Anindita, Ertel, Adam, Fedele, Carmine, Forsberg, Flemming, Fortina, Paolo, Gabrilovich, Dmitry I., Harshyne, Larry A., Kean, Rhonda B., Kelly, William K., Kossenkov, Andrew V., Krishn, Shiv Ram, Kurtoglu, Senem, Languino, Lucia R., Liu, Qin, Lu, Huimin, Speicher, David W., Stanczak, Maria, Tang, Hsin-Yao, Wang, Kerith, Weinreb, Paul H., Yu, Lei   +23 more
core   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

Photochemistry and Photobiology, Volume 102, Issue 2, Page 370-399, March/April 2026.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima, Rebeca Barros Nascimento, Ana Paula Mariano Santos Ginez, Maria Stella Moreira, Rebeca Boltes Cecatto, Rodrigo Labat Marcos, Maria Fernanda Setúbal Destro Rodrigues   +6 more
wiley   +1 more source

Clinical Significance of Urine Heparanase in Bladder Cancer Progression

Neoplasia: An International Journal for Oncology Research, 2008
Heparanase is an endo-β-glucuronidase capable of cleaving heparan sulfate (HS), an activity implicated in tumor metastasis. Heparanase expression is upregulated in primary human tumors, correlating with reduced post operative survival and elevated ...
Itay Shafat, Dov Pode, Tamar Peretz, Neta Ilan, Israel Vlodavsky, Nisman Benjamin   +5 more
doaj   +1 more source

Heparanase: a potential marker of worse prognosis in estrogen receptor-positive breast cancer

npj Breast Cancer, 2021
Heparanase promotes tumor growth in breast tumors. We now evaluated heparanase protein and gene-expression status and investigated its impact on disease-free survival in order to gain better insight into the role of heparanase in ER-positive (ER+) breast
Tamar Zahavi, Mali Salmon-Divon, Roberto Salgado, Michael Elkin, Esther Hermano, Ariel M. Rubinstein, Prudence A. Francis, Angelo Di Leo, Giuseppe Viale, Evandro de Azambuja, Lieveke Ameye, Christos Sotiriou, Asher Salmon, Nataly Kravchenko-Balasha, Amir Sonnenblick   +14 more
doaj   +1 more source

Proteoglycans and osteolysis. [PDF]

, 2012
Osteolysis is a complex mechanism resulting from an exacerbated activity of osteoclasts associated or not with a dysregulation of osteoblast metabolism leading to bone loss.
A Bruzzaniti, A Corsi, A Irie, A Kumarasuriyar, A-V Rousselle, BA Mosheimer, C Blin-Wakkach, C Damiens, CJ Robinson, D Heymann, E Pivetta, EJ Chang, F Gouin, F Lamoureux, F Lamoureux, F Lézot, H Yasuda, HJ Knowles, J Folwarczna, J Guicheux, JJ Cao, JM Muir, JM Muir, K Chu, K Fuller, K Nakano, K Shinmyouzu, K Yamaguchi, L Duplomb, L Duplomb, L Ling, LA Barbour, LM Haupt, M Baud’huin, M Baud’huin, M Baud’Huin, M Baud’huin, M Presta, P Spessotto, PJ Marie, R Rajgopal, S Georges, S Theoleyre, S Theoleyre, S Théoleyre, SJ Song, SM Cool, SW Fox, T Miyazaki, T Standal, V Kram, W Ariyoshi, WC Raschke, WJ Boyle, WS Simonet, X Jiao, Y Bi, Y Bi, Y Wittrant, YY Kong   +59 more
core   +4 more sources

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

The FEBS Journal, Volume 293, Issue 1, Page 26-41, January 2026.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou, Sylvia Mangani, Nikolaos E. Koletsis, Christos Koutsakis, Nicholas S. Mastronikolis, Marco Franchi, Nikos K. Karamanos   +6 more
wiley   +1 more source

Matrix Metalloproteinases in Cytotoxic Lymphocytes Impact on Tumour Infiltration and Immunomodulation [PDF]

, 2010
To efficiently combat solid tumours, endogenously or adoptively transferred cytotoxic T cells and natural killer (NK) cells, need to leave the vasculature, traverse the interstitium and ultimately infiltrate the tumour mass.
Karin Edsparr, Per H. Basse, Ronald H. Goldfarb, Per Albertsson   +3 more
core   +1 more source