Results 41 to 50 of about 162,168 (205)

An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals

Scientific Reports
Rapidly waning immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires continued global access to affordable vaccines. Globally, inactivated SARS-CoV-2 vaccines have been widely used during the SARS-CoV-2 pandemic.
Anna Offersgaard, Carlos R. Duarte Hernandez, Yuyong Zhou, Zhe Duan, Karen Anbro Gammeltoft, Katrine T. Hartmann, Ulrik Fahnøe, Pavel Marichal-Gallardo, Garazi Peña Alzua, Alexander P. Underwood, Christina Sølund, Nina Weis, Jesper Hansen Bonde, Jan P. Christensen, Gabriel K. Pedersen, Henrik Elvang Jensen, Kenn Holmbeck, Jens Bukh, Judith Margarete Gottwein   +18 more
doaj   +1 more source

Chinese medicine in the treatment of autoimmune hepatitis: Progress and future opportunities

Animal Models and Experimental Medicine, 2022
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease occurring in individuals of all ages with a higher incidence in females and characterized by hypergammaglobulinemia, elevated serum autoantibodies and histological features of interface ...
Jia Liu, Zhi Ma, Han Li, Xiaojiaoyang Li
doaj   +1 more source

Seroprevalence of Hepatitis A virus infection in non-human primates in Assam, India

Journal of Threatened Taxa, 2013
The present study investigated 37 serum samples of non-human primates in Assam State Zoo and the Department of Forest and Environment, Govt. of Assam for seroprevalence of hepatitis A virus infection during the period from December, 2007 to November ...
B.G. Nath, A. Chakraborty, D.K. Sarma, T. Rahman, P.K. Boro   +4 more
doaj   +1 more source

Experimental Models of COVID-19

Frontiers in Cellular and Infection Microbiology, 2022
COVID-19 is the most consequential pandemic of the 21st century. Since the earliest stage of the 2019-2020 epidemic, animal models have been useful in understanding the etiopathogenesis of SARS-CoV-2 infection and rapid development of vaccines/drugs to ...
Luis A. Caldera-Crespo, Luis A. Caldera-Crespo, Michael J. Paidas, Sabita Roy, Carl I. Schulman, Norma Sue Kenyon, Norma Sue Kenyon, Norma Sue Kenyon, Sylvia Daunert, Sylvia Daunert, Sylvia Daunert, Arumugam R. Jayakumar   +11 more
doaj   +1 more source

Hepatitis E virus is prevalent in the pig population of Lao People's Democratic Republic and evidence exists for homogeneity with Chinese Genotype 4 human isolates

, 2011
The objective of this study was to determine the prevalence and genotypic range of Hepatitis E virus (HEV) in the pig population of northern Lao People's Democratic Republic (PDR).
Jarman, R.G., Khamphouth Vongxay, Thompson, R.C.A., Blacksell, SD, Chinnawirotpisan, P, Vongxay, K., Melanie C. Melendrez, Thompson, RC, Melendrez, MC, Conlan, JV, Stanley Fenwick, Stuart D. Blacksell, Thompson, RCA, James V. Conlan, Conlan, J., Blacksell, S.D., R.C. Andrew Thompson, Chinnawirotpisan, P., Richard G. Jarman, Fenwick, S., Melendrez, M.C., Jarman, RG, Vongxay, K, Fenwick, S, Piyawan Chinnawirotpisan   +24 more
core   +1 more source

Full-Genome Hepatitis B Virus Genotyping: A Juxtaposition of Next-Generation and Clone-Based Sequencing Approaches—Comparing Genotyping Methods of Hepatitis B Virus

Viruses
Background: The enhanced sensitivity of next-generation sequencing (NGS) for assessing hepatitis B virus (HBV) quasispecies heterogeneity over clone-based sequencing (CBS) is well documented.
Li-Ping Hu, Qin-Yan Chen, Mei-Lin Huang, Wen-Jia Zhang, Xiao-Qian Huang, Xian-Feng Yi, Hui-Hua Jia   +6 more
doaj   +1 more source

Hepatitis E: A disease of reemerging importance

Journal of the Formosan Medical Association, 2015
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide. Originally considered to be restricted to humans, it is now clear that HEV and HEV-like viruses have several animal reservoirs with complex ecology and genetic diversity,
Siddharth Sridhar, Susanna K.P. Lau, Patrick C.Y. Woo   +2 more
doaj   +1 more source

Seroprevalence of various viral diseases in Tamil Nadu, India

Journal of Global Infectious Diseases, 2023
Introduction: Virus-borne diseases have recently gained significant public health importance. Viruses infect several hosts, including animal reservoirs, evolve quickly, and recombine emerging and reemerging to pose recurring dangers to humans.
R Gopinath, A L Meenakshi Sundaram, A Dhanasezhian, M Arundadhi, G Sucila Thangam   +4 more
doaj   +1 more source

Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques

Nature Communications, 2017
Hepatitis B virus (HBV) has a limited host range and current animal models can only recapitulate certain aspects of HBV replication. Here, the authors show that expression of the HBV receptor NTCP in macaques supports HBV replication in vivo, suggesting ...
Benjamin J. Burwitz, Jochen M. Wettengel, Martin A. Mück-Häusl, Marc Ringelhan, Chunkyu Ko, Marvin M. Festag, Katherine B. Hammond, Mina Northrup, Benjamin N. Bimber, Thomas Jacob, Jason S. Reed, Reed Norris, Byung Park, Sven Moller-Tank, Knud Esser, Justin M. Greene, Helen L. Wu, Shaheed Abdulhaqq, Gabriela Webb, William F. Sutton, Alex Klug, Tonya Swanson, Alfred W. Legasse, Tania Q. Vu, Aravind Asokan, Nancy L. Haigwood, Ulrike Protzer, Jonah B. Sacha   +27 more
doaj   +1 more source

Humanized chimeric mouse models of hepatitis B virus infection

International Journal of Infectious Diseases, 2017
Hepatitis B virus (HBV) infection is associated with an increased risk of hepatic cirrhosis, hepatocellular carcinoma, fulminant hepatitis and end-stage hepatic failure. Despite the availability of anti-HBV therapies, HBV infection remains a major global
Suwan Sun, Jun Li
doaj   +1 more source