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Natural reservoirs for homologs of hepatitis C virus
Emerging Microbes and Infections, 2014 Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the human population. Hepatitis C virus infection causes acute and chronic liver disease, including chronic hepatitis, cirrhosis and hepatocellular carcinoma.
Stephanie Pfaender +3 more
doaj +1 more source
Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]
, 2012 Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin +5 more
core +1 more source
Frontiers in Microbiology, 2023 IntroductionPaslahepevirus balayani (Hepatitis E virus; HEV) is an emerging virus that poses as a public health threat. The virus is now reported to be the leading cause of acute viral hepatitis, with a unique impact on African settings.
Adeolu S. Oluremi +13 more
doaj +1 more source
Animal Models of Chronic Hepatitis Delta Virus Infection Host–Virus Immunologic Interactions
Pathogens, 2015 Hepatitis delta virus (HDV) is a defective RNA virus that has an absolute requirement for a virus belonging to the hepadnaviridae family like hepatitis B virus (HBV) for its replication and formation of new virions.
Rafael Aldabe +3 more
doaj +1 more source
JHEP Reports, 2022 Background & Aims: HBV has a narrow host restriction, with humans and chimpanzees representing the only known natural hosts. The molecular correlates of resistance in species that are commonly used in biomedical research, such as mice, are currently ...
Lei Wei +6 more
doaj +1 more source
The course of hepatitis E virus infection in pigs after contact-infection and intravenous inoculation [PDF]
, 2009 Background Worldwide, hepatitis E virus (HEV) genotype 3 is observed in pigs and transmission to humans is implied. To be able to estimate public health risks from e.g.
Bouwknegt Martijn +26 more
core +1 more source
Animal models of acute hepatic failure [PDF]
International Journal of Experimental Pathology, 2000 The understanding and treatment of acute hepatic failure has developed rapidly over the last 40 years reducing morbidity and mortality from this syndrome. Progress has been made by the study of animal models that reflect the clinical, biochemical and histological pattern of the syndrome seen in man.
T M, Rahman, H J, Hodgson
openaire +2 more sources
Interferon signaling in viral hepatitis [PDF]
, 2013 Hepatitis C virus (HCV) is a single stranded positive RNA virus classified in 6 different genotypes. Hepatocytes are the main targets of HCV infection. It has been estimated that 60 to 70% of the infected patients develop chronic infection.
Trincucci, Gaia
core +1 more source
BMC Infectious Diseases, 2018 Background Hepatitis E virus (HEV) is a leading cause of hepatitis worldwide. However, its infection biology and pathogenesis remain largely elusive. Furthermore, no proven medication is available for treating hepatitis E.
Wenhai Yu +4 more
doaj +1 more source
Hepatitis E Virus and Related Viruses in Animals [PDF]
Transboundary and Emerging Diseases, 2015 Hepatitis E is an acute human liver disease in healthy individuals which may eventually become chronic. It is caused by the hepatitis E virus (HEV) and can have a zoonotic origin. Nearly 57,000 people die yearly from hepatitis E-related conditions. The disease is endemic in both developing and developed countries with distinct epidemiologic profiles ...
Thiry, D. +6 more
openaire +3 more sources