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IntroductionPaslahepevirus balayani (Hepatitis E virus; HEV) is an emerging virus that poses as a public health threat. The virus is now reported to be the leading cause of acute viral hepatitis, with a unique impact on African settings.
Adeolu S. Oluremi +13 more
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Animal Models of Hepatitis B Virus Infection–Success, Challenges, and Future Directions
Chronic hepatitis B virus (HBV) infection affects more than 250 million people worldwide, which greatly increases the risk for terminal liver diseases, such as liver cirrhosis and hepatocellular carcinoma (HCC).
Yongzhen Liu +2 more
doaj +1 more source
Background & Aims: HBV has a narrow host restriction, with humans and chimpanzees representing the only known natural hosts. The molecular correlates of resistance in species that are commonly used in biomedical research, such as mice, are currently ...
Lei Wei +6 more
doaj +1 more source
Background Hepatitis E virus (HEV) is a leading cause of hepatitis worldwide. However, its infection biology and pathogenesis remain largely elusive. Furthermore, no proven medication is available for treating hepatitis E.
Wenhai Yu +4 more
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Hepatitis E Virus and Related Viruses in Animals [PDF]
Hepatitis E is an acute human liver disease in healthy individuals which may eventually become chronic. It is caused by the hepatitis E virus (HEV) and can have a zoonotic origin. Nearly 57,000 people die yearly from hepatitis E-related conditions. The disease is endemic in both developing and developed countries with distinct epidemiologic profiles ...
Thiry, D. +6 more
openaire +3 more sources
HCV Animal Models: A Journey of More than 30 Years
In the 1970s and 1980s it became increasingly clear that blood transfusions could induce a form of chronic hepatitis that could not be ascribed to any of the viruses known to cause liver inflammation.
Philip Meuleman, Geert Leroux-Roels
doaj +1 more source
Hepatitis delta virus RNA decline post-inoculation in human NTCP transgenic mice is biphasic
Chronic infection with hepatitis B and delta viruses (HDV) is the most serious form of viral hepatitis due to more severe manifestations of an accelerated progression to liver fibrosis, cirrhosis, and hepatocellular carcinoma.
Stephanie Maya +10 more
doaj +1 more source
Hepatitis C is a global health problem caused by infection with the hepatitis C virus. Although representative prevalence data are not available from many countries, available data indicate that approximately 3% of the world's population is infected with
A.R. ZANETTI +1 more
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Viral hepatitis E: A disease of humans and animals [PDF]
The hepatitis E virus is ubiquitous in all parts of the world where pig production exists. The infection occurs in several animal species and its course is mostly asymptomatic. Viral strains isolated from pigs and humans are genetically similar,
Kureljušić Branislav +4 more
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We examined correlates of antinuclear antibody (ANA) positivity (ANA+) in individuals with chronic hepatitis C virus (HCV) infection and the effect of positivity on clinical outcome of HCV. Pretreatment sera from 645 patients from three centres in Sweden
Marshall, S +22 more
core +1 more source

