Results 11 to 20 of about 1,894,434 (309)

Targeting Host Innate and Adaptive Immunity to Achieve the Functional Cure of Chronic Hepatitis B

Vaccines, 2020
Despite the availability of an effective preventive vaccine for hepatitis B virus (HBV) for over 38 years, chronic HBV (CHB) infection remains a global health burden with around 257 million patients. The ideal treatment goal for CHB infection would be to
Sayeh Ezzikouri, Mohammad Enamul Hoque Kayesh, Soumaya Benjelloun, Michinori Kohara, Kyoko Tsukiyama-Kohara   +4 more
doaj   +1 more source

Characterization of innate immune response to hepatitis B virus genotype F acute infection in tree shrew (Tupaia belangeri) model

Frontiers in Virology, 2022
Hepatitis B virus (HBV) infection is a global public health problem. The clinical outcomes of HBV infections are influenced by host as well as viral factors, including viral genotypes and subgenotypes.
Mohammad Enamul Hoque Kayesh, Mohammad Enamul Hoque Kayesh, Mohammad Enamul Hoque Kayesh, Md Abul Hashem, Md Abul Hashem, Takahiro Sanada, Bouchra Kitab, Bouchra Kitab, Md Haroon Or Rashid, Md Haroon Or Rashid, Lipi Akter, Sayeh Ezzikouri, Shuko Murakami, Shintaro Ogawa, Yasuhito Tanaka, Michinori Kohara, Kyoko Tsukiyama-Kohara, Kyoko Tsukiyama-Kohara   +17 more
doaj   +1 more source

Zoonotic Hepatitis E Virus: Classification, Animal Reservoirs and Transmission Routes

Viruses, 2016
During the past ten years, several new hepatitis E viruses (HEVs) have been identified in various animal species. In parallel, the number of reports of autochthonous hepatitis E in Western countries has increased as well, raising the question of what role
Virginie Doceul, Eugénie Bagdassarian, Antonin Demange, Nicole Pavio   +3 more
doaj   +1 more source

The CYP2D6 animal model: how to induce autoimmune hepatitis in mice [PDF]

, 2012
Autoimmune hepatitis is a rare but life threatening autoimmune disease of the liver of unknown etiology1,2. In the past many attempts have been made to generate an animal model that reflects the characteristics of the human disease 3-5.
Christen, Urs, Hintermann, Edith, Ehser, Janine   +2 more
core   +1 more source

Natural reservoirs for homologs of hepatitis C virus

Emerging Microbes and Infections, 2014
Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the human population. Hepatitis C virus infection causes acute and chronic liver disease, including chronic hepatitis, cirrhosis and hepatocellular carcinoma.
Stephanie Pfaender, Richard JP Brown, Thomas Pietschmann, Eike Steinmann   +3 more
doaj   +1 more source

Estimation of hepatitis E virus transmission among pigs due to contact-exposure [PDF]

, 2008
Locally acquired hepatitis E in humans from industrialized countries has been repeatedly suggested to originate from pigs. Pigs may serve as a reservoir of hepatitis E virus (HEV) for humans when a typical infected pig causes on average more than one ...
Saskia A. Rutjes, Wellenberg, Gerard, van der Poel, W.H.M., Rutjes, Saskia, de Jong, Mart, Frankena, K., de Jong, M.C.M., Rutjes, S.A., van Der Poel, Wim, Poel, W.H.M., van der, Martijn Bouwknegt, Frankena, Klaas, Roda Husman, A.M., de, Mart C.M. de Jong, Gerard J. Wellenberg, Bouwknegt, M., Jong, M.C.M., de, Klaas Frankena, Wellenberg, G.J., de Roda Husman, A.M., Ana Maria de Roda Husman, Bouwknegt, Martijn, Wim H.M. van der Poel, de Roda Husman, Ana Maria   +23 more
core   +1 more source

Animal models of acute hepatic failure [PDF]

International Journal of Experimental Pathology, 2000
The understanding and treatment of acute hepatic failure has developed rapidly over the last 40 years reducing morbidity and mortality from this syndrome. Progress has been made by the study of animal models that reflect the clinical, biochemical and histological pattern of the syndrome seen in man.
T M, Rahman, H J, Hodgson
openaire   +2 more sources

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]

, 2012
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin, Sanford, Brenton J, Kenney, Scott P, Dryman, Barbara A, Córdoba, Laura, Opriessnig, Tanja   +5 more
core   +1 more source

Epidemiology of Occult Hepatitis B Infection Among Thalassemic, Hemophilia, and Hemodialysis Patients [PDF]

, 2012
Context: Hepatitis B virus (HBV) is the most common disease commuted through blood transfusion. Occult hepatitis B infection (OBI) is a form of the disease which does not present Hepatitis B surface antigens (HBsAg) in the serum of patients; however ...
Ahmadabadi, Behzad Nasiri, Kennedy, Derek, Derek Kennedy, Behzad Nasiri Ahmadabadi, Mohammad Kazemi Arababadi, Arababadi, Mohammad Kazemi, Hassan Yousefi Daredor, Daredor, Hassan Yousefi   +7 more
core   +1 more source

Animal Models of Chronic Hepatitis Delta Virus Infection Host–Virus Immunologic Interactions

Pathogens, 2015
Hepatitis delta virus (HDV) is a defective RNA virus that has an absolute requirement for a virus belonging to the hepadnaviridae family like hepatitis B virus (HBV) for its replication and formation of new virions.
Rafael Aldabe, Lester Suárez-Amarán, Carla Usai, Gloria González-Aseguinolaza   +3 more
doaj   +1 more source