Results 11 to 20 of about 20,528,118 (294)

Hepatitis B virus X protein accelerates the development of hepatoma

open access: yesCancer Biology & Medicine, 2014
The chronic infection of hepatitis B virus (HBV) is closely related to the occurrence and development of hepatocellular carcinoma (HCC). Accumulated evidence has shown that HBV X protein (HBx protein) is a multifunctional regulator with a crucial role in
Xiao-Dong Zhang, Yuan Wang, Li-Hong Ye
doaj   +3 more sources

Modulation of Apoptotic Signaling by the Hepatitis B Virus X Protein

open access: yesViruses, 2012
Worldwide, an estimated 350 million people are chronically infected with the Hepatitis B Virus (HBV); chronic infection with HBV is associated with the development of severe liver diseases including hepatitis and cirrhosis.
Michael J. Bouchard   +2 more
doaj   +3 more sources

Hepatitis B Virus Protein X Induces Degradation of Talin-1 [PDF]

open access: yesViruses, 2016
In the infected human hepatocyte, expression of the hepatitis B virus (HBV) accessory protein X (HBx) is essential to maintain viral replication in vivo.
Maarten A. A. van de Klundert   +3 more
doaj   +3 more sources

Naringenin attenuates hepatitis B virus X protein-induced hepatic steatosis

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Naringenin (Nar), a common dietary flavonoid abundantly present in fruits, vegetables, and Chinese herbs, is believed to possess strong anti-inflammatory properties and to modulate hepatic apolipoprotein and lipid synthesis. However, there are
Hung-Jen Lin   +3 more
doaj   +3 more sources

Deregulation of Epigenetic Mechanisms by the Hepatitis B Virus X Protein in Hepatocarcinogenesis [PDF]

open access: yesViruses, 2013
This review focuses on the significance of deregulation of epigenetic mechanisms by the hepatitis B virus (HBV) X protein in hepatocarcinogenesis and HBV replication.
Ourania M. Andrisani
doaj   +3 more sources

Hepatitis B Virus X Protein and Hepatocarcinogenesis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Chronic hepatitis B virus (HBV) infection is one of the most associated factors in hepatocarcinogenesis. HBV is able to integrate into the host genome and encode the multi-functional hepatitis B virus x protein (HBx). Although the mechanism between HBx and carcinogenesis is still elusive, recent studies have shown that HBx was able to influence various
Liu, S, Koh, S.S.Y, Lee, C.G.L
openaire   +3 more sources

The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B [PDF]

open access: yesHepatology, 2019
Chronic infection of hepatitis B virus (HBV) is associated with an increased incidence of hepatocellular carcinoma (HCC). HBV encodes an oncoprotein, hepatitis B x protein (HBx), that is crucial for viral replication and interferes with multiple cellular activities including gene expression, histone modifications, and genomic stability.
Ren, Laifeng   +21 more
openaire   +3 more sources

Gene X Two Triple Mutations Predominance on Chronic Hepatitis B Virus in Padang, West Sumatra Indonesia

open access: yesThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Background: Hepatitis B is a health issue that become major problem worldwide with high morbidity. Hepatitis B is a liver infection that caused by Hepatitis B Virus.
Afida Razuna Ave   +2 more
doaj   +1 more source

Stimulation of Cellular Proliferation by Hepatitis B Virus X Protein [PDF]

open access: yesDisease Markers, 2001
Chronic infection with the hepatitis B virus (HBV) is a known risk factor in the development of human hepatocellular carcinoma (HCC). The HBV‐encoded X protein, HBx, has been investigated for properties that may explain its cancer cofactor role in transgenic mouse lines.
Madden, Charles R., Slagle, Betty L.
openaire   +2 more sources

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