Results 11 to 20 of about 380,993 (362)
Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]
, 2012 BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen +5 more
core +8 more sources
Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]
, 2020 Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea +6 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2020 Extracellular vesicles (EVs) are nano-sized membrane-limited organelles that are liberated from their producer cells, traverse the intercellular space, and may interact with other cells resulting in the uptake of the EV molecular payload by the recipient
Xinlei Li +4 more
doaj +1 more source
Hepatoprotective Effect of Solanum melongena/Eggplant against Acute Hepatitis
Althea Medical Journal, 2015 Background: Hepatitis is a liver inflammation that can be acute or chronic and may cause damage to hepatocytes such as necrosis.. Hepatocyte necrosis can be inhibited by antioxidants such as flavonoids found in Solanum melongena fruit.
Nabhan Komara +2 more
doaj +1 more source
Cells, 2022 Autophagy performs essential cell functions in the liver through an intracellular lysosomal degradation process. Several studies have reported that autophagy deficiency can lead to liver injury, including hepatic fibrosis; however, the mechanisms ...
Hye-Young Seo +5 more
doaj +1 more source
Revista Española de Enfermedades Digestivas, 2019 We have read with great interest the study by Vera MC et al. on the intrasplenic transplantation of hepatocytes from donors receiving the carcinogenic drugs diethylnitrosamine (DEN) and 2-actylaminofluorene (2-AAF). The most important conclusion of the study is that there were no signs of tumor progression in the recipient liver at seven and 60 days ...
Javier A, Cienfuegos +2 more
openaire +2 more sources
Intercellular communication in normal and regenerating rat liver: a quantitative analysis [PDF]
, 1981 We have compared intercellular communication in the regenerating and normal livers of weanling rats. The electrophysiological studies were conducted at the edge of the liver, and we have found that here as elsewhere in the liver there is a dramatic ...
Meyer, David J. +3 more
core +2 more sources
eLife, 2019 Hepatocellular carcinoma (HCC) is a deadly human cancer associated with chronic inflammation. The cytosolic pathogen sensor NLRP12 has emerged as a negative regulator of inflammation, but its role in HCC is unknown.
SM Nashir Udden +8 more
doaj +1 more source
Dynamics of Hepatitis B Virus Covalently Closed Circular DNA: A Mini-Review
Microorganisms, 2023 Eradication of cccDNA is an ideal goal of chronic hepatitis B (CHB) therapy. Understanding the changes in the cccDNA pool during therapy provides a basis for developing CHB treatment strategies.
Jie-Li Hu, Ai-Long Huang
doaj +1 more source
Isolated Hepatocytes versus Hepatocyte Spheroids: In Vitro Culture of Rat Hepatocytes [PDF]
Cell Transplantation, 2005 The use of hepatocytes that express liver-specific functions to develop an artificial liver is promising. Unfortunately, the loss of specialized liver functions (dedifferentiation) is still a major problem. Different techniques, such as collagen entrapment, spherical multicellular aggregates (spheroids), and coculture of hepatocytes with extracellular
Giovanni Ambrosino +5 more
openaire +4 more sources