Results 211 to 220 of about 628,453 (389)

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

open access: yesAdvanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen   +14 more
wiley   +1 more source

The Interplay Between Cellular Senescence and Lipid Metabolism in the Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). [PDF]

open access: yesInt J Mol Sci
Mastoridou EM   +7 more
europepmc   +1 more source

A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting [PDF]

open access: diamond, 2012
Sarah E. Hugo   +5 more
openalex   +1 more source

Mixed lineage kinase 3 mediates release of C‐X‐C motif ligand 10–bearing chemotactic extracellular vesicles from lipotoxic hepatocytes

open access: yesHepatology, 2016
Samar H. Ibrahim   +8 more
semanticscholar   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

open access: yesAdvanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng   +20 more
wiley   +1 more source

Free Fatty Acids and Endotoxins Synergically Induce Pyroptosis in Bovine Hepatocytes. [PDF]

open access: yesMetabolites
Li D   +10 more
europepmc   +1 more source

Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

open access: yesHepatology, 2016
M. Thomsen   +11 more
semanticscholar   +1 more source

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