Results 111 to 120 of about 34,396 (232)

Immunity, Inflammation and Heart Failure: Their Role on Cardiac Function and Iron Status [PDF]

, 2019
Aims: Heart failure is a clinical syndrome characterized by subclinical systemic inflammation and immune system activation associated with iron deficiency.
Corrao S., Gigliotti S., Greco M., Hribal M. L., Miceli S., Perticone F., Perticone M., Pinto A., Sesti G., Suraci E., Zito R.   +10 more
core   +1 more source

Anaemia and Maternal Iron Intakes in Pregnancy and Child Asthma: An Observational Analysis From a Longitudinal Cohort

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Evidence supporting the association between anaemia and lower iron intakes during pregnancy with an increased risk of childhood asthma remains unclear. This study aimed to investigate whether (i) lower haemoglobin or anaemia in late pregnancy and (ii) lower mean dietary iron intake in pregnancy were associated with a higher
Emma Hokey, Sophie Callanan, Anna Delahunt, Alexander Douglass, Mohammad Talaei, Seif O. Shaheen, Fionnuala M. McAuliffe   +6 more
wiley   +1 more source

Silencing airway epithelial cell-derived hepcidin exacerbates sepsis-induced acute lung injury [PDF]

, 2014
INTRODUCTION: The production of antimicrobial peptides by airway epithelial cells is an important component of the innate immune response to pulmonary infection and inflammation. Hepcidin is a β-defensin-like antimicrobial peptide and acts as a principal
Cong Li Zeng, Jun Lu Wang, Qi Xing Chen, Qing Hua Chen, Sheng Wen Song, Xia Zheng, Xiang Ming Fang   +6 more
core   +1 more source

Mast Cell‐Derived CXCL4: A Key Mediator of Ferroptosis and Cardiac Damage in Septic Cardiomyopathy

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Septic cardiomyopathy (SCM) is a common and life‐threatening complication of severe sepsis, with high mortality due to unclear underlying mechanisms. CXCL4, a key pro‐inflammatory factor, is implicated in various heart diseases, while ferroptosis (iron and lipid hydrogen peroxide‐dependent regulated cell death) plays a crucial role ...
Jing Wei, Zhi‐ying Jiang, Ling‐feng Ye, Hong‐xiang Lu   +3 more
wiley   +1 more source

The α1‐adrenergic receptor is involved in hepcidin upregulation induced by adrenaline and norepinephrine via the STAT3 pathway [PDF]

, 2018
Elevated body iron stores are associated with hypertension progression, while hypertension is associated with elevated plasma catecholamine levels in patients. However, there is a gap in our understanding of the connection between catecholamines and iron
Bao, Yongping, Chang, Yan-Zhong, Ci, Yunzhe, Cui, Yanmei, Fu, Yu-Jian, Kong, Wei-Na, Lei, Yuhua, Xie, Lide, Zhao, Shu-E, Zhao, Shuqiang   +9 more
core   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Expression of functional recombinant human tissue transglutaminase (TG2) using the bac-to-bac baculovirus expression system [PDF]

, 2016
Purpose: Tissue transglutaminase (TG2) is a unique multifunctional enzyme. The enzyme possesses enzymatic activities such as transamidation/crosslinking and non-enzymatic functions such as cell migration and signal transduction.
Azari, S., Kalhor, H.R., Yazdani, Y.
core   +2 more sources

BiGraph‐DTA: Predicting drug–target interactions of hepatoprotective agents with graph convolutional networks

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract Predicting drug–target affinity (DTA) is critical for discovering and developing hepatoprotective agents that can prevent and treat liver diseases. In this study, we propose BiGraph‐DTA, a new predictive model for identifying DTA score prediction for hepatoprotective compounds by combining graph convolutional networks and bidirectional long ...
Arief Sartono, Bambang Riyanto Trilaksono, Sophi Damayanti, Anto Satriyo Nugroho, Firdayani Firdayani   +4 more
wiley   +1 more source

Evolution of Th2 responses : Characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity [PDF]

, 2017
Acknowledgements This research was funded by the European Commission under the 7th Framework Programme for Research and Technological Development (FP7) of the European Union (Grant Agreement 311993 TARGETFISH). T.W.
A Antczak, A Bhattacharjee, A Munitz, AE Lockyer, E Wangkahart, EJ Song, F Buonocore, F Takizawa, G Biswas, G Scapigliati, H Nielsen, J Zhu, J Zou, JE Allen, JH Li, JW Hodgkinson, K Bao, K Tamura, L-y Zhu, LM Braden, M Howard, M Ohtani, M Tine, M Wills-Karp, MG Reese, MM Costa, MO Huising, N Nunez Ortiz, PJ Lupardus, RC Edgar, RL Coffman, S Almeria, S Kumar, S McCormick, SP Gadani, T Hage, T Maehr, T Wang, T Wang, T Wang, T Wang, T Yamaguchi, T Yamaguchi, TA Wynn, TA Wynn   +44 more
core   +1 more source

First Case Report of Precursor‐Targeted Immune‐Mediated Anaemia in a Dog From Italy Lacking Rubriphagocytosis and With Severe Hyperferraemia: Diagnosis, Treatment, and Clinical Outcome

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
ABSTRACT Precursor‐targeted immune‐mediated anaemia (PIMA) is an uncommon and poorly understood cause of persistent non‐regenerative anaemia in dogs and cats, characterised by ineffective erythropoiesis and frequently associated with rubriphagocytosis (RP) in bone marrow samples.
Souad Nasar, Annamaria Uva, Giovanna Girardi, Giulia Tanas, Stefano Ciccarelli, Andrea Zatelli, Maria Alfonsa Cavalera, Floriana Gernone   +7 more
wiley   +1 more source