Results 31 to 40 of about 1,887 (167)
Hepcidin: inflammation versus hypoxia [PDF]
Sleep and Breathing, 2014 The finding of periodic leg movements (PLM) during polysomnographic recordings is a relatively common phenomenon. PLM is associated with a variety of sleep disorders [1, 2] and other diseases. An association between obstructive sleep apnea (OSA) and PLM [3–5] has been clearly established.
F, del Campo, C, Zamarrón
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Hepcidin-Dependent Regulation of Erythropoiesis during Anemia in a Teleost Fish, Dicentrarchus labrax. [PDF]
PLoS ONE, 2016 Anemia is a common disorder, characterized by abnormally low levels of red blood cells or hemoglobin. The mechanisms of anemia development and response have been thoroughly studied in mammals, but little is known in other vertebrates, particularly ...
João V Neves +3 more
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Hepcidin in hepatocellular carcinoma
British Journal of Cancer, 2022 AbstractHepatocellular carcinoma (HCC) is one of the most common reasons for cancer-related deaths. Excess iron increases HCC risk. Inevitably, hepcidin, the iron hormone that maintains systemic iron homoeostasis is involved in HCC pathology. Distinct from other cancers that show high hepcidin expression, HCC patients can show low hepcidin levels. Thus,
Jonathan H. Joachim, Kosha J. Mehta
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Biology, 2021 The black rockfish, Sebastes schlegelii, is a typical viviparous teleost, which belongs to the family Scorpaenidae. Due to its high economic and ecological values, S. schlegelii has been widely cultured in East Asian countries.
Min Zhang +6 more
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Hepcidin antagonists for potential treatments of disorders with hepcidin excess [PDF]
Frontiers in Pharmacology, 2014 The discovery of hepcidin clarified the basic mechanism of the control of systemic iron homeostasis. Hepcidin is mainly produced by the liver as a propeptide and processed by furin into the mature active peptide. Hepcidin binds ferroportin, the only cellular iron exporter, causing the internalization and degradation of both.
POLI, Maura +4 more
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Brazilian Journal of Nephrology, 2020 Backgrounds: Hepcidin is related to the pathogenesis of chronic renal failure anemia, which is considered a chronic inflammatory state as well as HCV infection.
Yasser B.M. Ali +4 more
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Electronic Journal of Biotechnology, 2015 Background: Hepcidins, a kind of cysteine-rich antimicrobial peptides, play important roles in host immunological processes and iron regulation, which have been identified from several fish species.
Fei Ke +3 more
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In Vivo Effects of Pichia Pastoris-Expressed Antimicrobial Peptide Hepcidin on the Community Composition and Metabolism Gut Microbiota of Rats. [PDF]
PLoS ONE, 2016 Hepcidin, one kind of antimicrobial peptides, is one of the promising alternatives to antibiotics with broad spectrum of antimicrobial activity. Hepcidins cloned from different kinds of fishes have been produced using exogenous expression systems, and ...
Lanfang Tian +9 more
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An Overlooked Hepcidin–Cadmium Connection
International Journal of Molecular Sciences, 2022 Hepcidin (DTHFPICIFCCGCCHRSKCGMCCKT), an iron-regulatory hormone, is a 25-amino-acid peptide with four intramolecular disulfide bonds circulating in blood. Its hormonal activity is indirect and consists of marking ferroportin-1 (an iron exporter) for degradation.
Dawid Płonka +5 more
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Bulletin of the National Research Centre, 2020 Background Antimicrobial peptides were examined as an evolutionarily preserved component of the innate immune response and identified as a vital first-line defense against a broad spectrum of pathogens in fish.
Karima F. Mahrous +6 more
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