Results 31 to 40 of about 1,905 (175)

Hepcidin-Dependent Regulation of Erythropoiesis during Anemia in a Teleost Fish, Dicentrarchus labrax. [PDF]

open access: yesPLoS ONE, 2016
Anemia is a common disorder, characterized by abnormally low levels of red blood cells or hemoglobin. The mechanisms of anemia development and response have been thoroughly studied in mammals, but little is known in other vertebrates, particularly ...
João V Neves   +3 more
doaj   +1 more source

Teleost Piscidins—In Silico Perspective of Natural Peptide Antibiotics from Marine Sources

open access: yesAntibiotics, 2023
Fish, like all other animals, are exposed to constant contact with microbes, both on their skin and on the surfaces of their respiratory and digestive systems. Fish have a system of non-specific immune responses that provides them with initial protection
Patricia Asensio-Calavia   +5 more
doaj   +1 more source

Hepcidin

open access: yes, 2022
The hepcidin is antimicrobial peptide has antimicrobial effects discover before more than a thousand years; it has a great role in iron metabolism and innate immunity. Hepcidin is a regulator of iron homeostasis. Its production is increased by iron excess and inflammation and decreased by hypoxia and anemia.
Safa A. Faraj, Naeem M. Al-Abedy
openaire   +1 more source

Association between interleukin-6 gene polymorphism and iron regulation in hemodialysis patients infected with HCV

open access: yesBrazilian Journal of Nephrology, 2020
Backgrounds: Hepcidin is related to the pathogenesis of chronic renal failure anemia, which is considered a chronic inflammatory state as well as HCV infection.
Yasser B.M. Ali   +4 more
doaj   +2 more sources

Identification of Antimicrobial Peptide Genes in Black Rockfish Sebastes schlegelii and Their Responsive Mechanisms to Edwardsiella tarda Infection

open access: yesBiology, 2021
The black rockfish, Sebastes schlegelii, is a typical viviparous teleost, which belongs to the family Scorpaenidae. Due to its high economic and ecological values, S. schlegelii has been widely cultured in East Asian countries.
Min Zhang   +6 more
doaj   +1 more source

Molecular cloning and antibacterial activity of hepcidin from Chinese rare minnow (Gobiocypris rarus)

open access: yesElectronic Journal of Biotechnology, 2015
Background: Hepcidins, a kind of cysteine-rich antimicrobial peptides, play important roles in host immunological processes and iron regulation, which have been identified from several fish species.
Fei Ke   +3 more
doaj   +1 more source

In Vivo Effects of Pichia Pastoris-Expressed Antimicrobial Peptide Hepcidin on the Community Composition and Metabolism Gut Microbiota of Rats. [PDF]

open access: yesPLoS ONE, 2016
Hepcidin, one kind of antimicrobial peptides, is one of the promising alternatives to antibiotics with broad spectrum of antimicrobial activity. Hepcidins cloned from different kinds of fishes have been produced using exogenous expression systems, and ...
Lanfang Tian   +9 more
doaj   +1 more source

Hepcidin in hepatocellular carcinoma

open access: yesBritish Journal of Cancer, 2022
AbstractHepatocellular carcinoma (HCC) is one of the most common reasons for cancer-related deaths. Excess iron increases HCC risk. Inevitably, hepcidin, the iron hormone that maintains systemic iron homoeostasis is involved in HCC pathology. Distinct from other cancers that show high hepcidin expression, HCC patients can show low hepcidin levels. Thus,
Jonathan H. Joachim, Kosha J. Mehta
openaire   +3 more sources

Molecular characterization and expression analysis of hepc1 and hepc2 in three tilapia species collected from Lake Manzala

open access: yesBulletin of the National Research Centre, 2020
Background Antimicrobial peptides were examined as an evolutionarily preserved component of the innate immune response and identified as a vital first-line defense against a broad spectrum of pathogens in fish.
Karima F. Mahrous   +6 more
doaj   +1 more source

Antimicrobial Peptides from Fish

open access: yesPharmaceuticals, 2014
Antimicrobial peptides (AMPs) are found widely distributed through Nature, and participate in the innate host defense of each species. Fish are a great source of these peptides, as they express all of the major classes of AMPs, including defensins ...
Jorge A. Masso-Silva, Gill Diamond
doaj   +1 more source

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