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The Role of Microsatellite Instability in Endometrial Hyperplasia and Risk of Carcinoma Development. [PDF]

Biomedicines
Mollova-Kyosebekirova A, Uchikova E, Mihaylova A, Koleva-Ivanova M, Parahuleva M, Parahuleva N.   +5 more
europepmc   +1 more source

Gynecologic screening in hereditary nonpolyposis colorectal cancer

Gynecologic Oncology, 2003
In hereditary nonpolyposis colorectal cancer (HNPCC), women with a mismatch repair (MMR) gene mutation have a cumulative lifetime risk of 25-50% for endometrial cancer and 8-12% for ovarian cancer. Therefore, female members of HNPCC families are offered an annual gynecologic and transvaginal ultrasound (TVU) examination and serum level CA 125 analysis.
Marian J E Mourits, J H Kleibeuker, Ate G J Van Der Zee   +2 more
exaly   +5 more sources

Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

New England Journal of Medicine, 1998
Background Genetic disorders that predispose people to colorectal cancer include the polyposis syndromes and hereditary nonpolyposis colorectal cancer.
Lauri A Aaltonen, Reijo Salovaara, P Kristo   +2 more
exaly   +3 more sources

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Hereditary nonpolyposis colorectal cancer

Seminars in Surgical Oncology, 2000
Hereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, is the most common form of hereditary colorectal cancer (CRC). A well-orchestrated cancer family history is essential for its diagnosis since, unlike its familial adenomatous polyposis (FAP) hereditary cancer counterpart, HNPCC lacks distinguishing clinical stigmata of its cancer ...
H T, Lynch, J F, Lynch
openaire   +4 more sources

Hereditary Nonpolyposis Colorectal Cancer

Scandinavian Journal of Gastroenterology, 1994
(1994). Hereditary Nonpolyposis Colorectal Cancer. Scandinavian Journal of Gastroenterology: Vol. 29, No. 8, pp. 673-677.
J P, Mecklin, L B, Svendsen, P, Peltomäki, H F, Vasen   +3 more
openaire   +2 more sources