Results 41 to 50 of about 16,555 (261)

Patient‐Reported‐Outcome‐Measures (PROMs) After Gastrointestinal Endoscopic Resections

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Data on patient‐reported outcome measures (PROMs) of patients undergoing endoscopic resections have been sparse. The aim of our study was the prospective assessment of the Gastrointestinal Quality of Life Index (GIQLI) as a baseline and post‐endoscopic resection (ER) measurement in patients with epithelial mucosal neoplasms ...
Laura Retzbach, Karl‐Hermann Fuchs, Markus Brand, Thomas J. Lux, Alexander Meining   +4 more
wiley   +1 more source

Molecular diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome)

Revista de la Facultad de Medicina, 2016
Lynch syndrome is the most common cause of inherited colorectal cancer, totaling 5 to 8% of all the cases with high susceptibility to this type of cancer and extracolonic cancer.
David Serrano, Clara Eugenia Arteaga
doaj   +1 more source

Urothelial carcinoma: Perioperative considerations from top to bottom

CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 528-551, November/December 2025.
Abstract Urothelial carcinoma is an aggressive entity that is associated with significant morbidity, but there have been major advances in both our understanding of and treatment options for patients with this disease. In this review, the authors focus on novel therapeutic and diagnostic approaches in the perioperative setting, with an emphasis on ...
Wesley Yip, Salvador Jaime‐Casas, Anjaney Kothari, Mary Sullivan, Leslie K. Ballas, Domenique Escobar, Anne K. Schuckman, Jonathan E. Rosenberg, Jonathan A. Coleman   +8 more
wiley   +1 more source

ANALYSIS OF TP53, APC, KRAS, AND MMR GENETIC MUTATIONS IN COLORECTAL CANCER: A REVIEW ARTICLE [PDF]

Sanamed
Introduction: Colorectal cancer (CRC) is one of the most common malignancies with significant global health and economic implications. Genetic mutations in genes such as TP53, APC, KRAS, and MMR play a crucial role in the development and progression of ...
Gavric Igor, Hodzic Edin, Sarajlic Lana, Salibasic Mirhan, Bajramagic Salem, Dizdarevic Advan, Kulovic Edin   +6 more
doaj   +1 more source

Risk of colorectal cancer by family history of both colorectal carcinomas and colorectal polyps: a nationwide cohort study

Cancer Communications, Volume 45, Issue 11, Page 1407-1416, November 2025.
Abstract Background The increased risk of colorectal cancer (CRC) associated with family history of both colorectal in situ or invasive carcinomas (Stage 0 to IV) and colorectal polyps is attributed solely to family history of CRC, resulting in an underestimation of the actual risk. We aimed to assess the association between overall and early‐onset CRC
Yuqing Hu, Elham Kharazmi, Qunfeng Liang, Hermann Brenner, Jan Sundquist, Kristina Sundquist, Mahdi Fallah   +6 more
wiley   +1 more source

Mismatch repair genes founder mutations and cancer susceptibility in Lynch syndrome [PDF]

, 2015
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Alonso-Espinaco, Ashley-Koch, Baglietto, Behar, Berends, Boland, Borelli, Borelli, Borras, Caluseriu, Castellsague, Cavalli-Sforza, Cederquist, Chan, Chan, Chong, Clendenning, Clendenning, Desai, Dominguez-Valentin, Fishel, Fokkema, Foulkes, Froggatt, Froggatt, Goldberg, Gomez, Grindedal, Gruber, Gruber, Guo, Hendriks, Hiljadnikova-Bajro, Hitchins, Hitchins, Hutter, Jager, Jenkins, Karami, Kimura, Kwok, Lang, Lastella, Leon, Ligtenberg, Lohmann, Lopez-Escribano, Lynch, Lynch, Lynch, Lynch, Mangold, McPeek, Medina-Arana, Menendez, Miyaki, Moisio, Morak, Morral, Mur, Nicolaides, Niell, Nystrom-Lahti, Olsson, Palomaki, Papadopoulos, Peltomaki, Pensotti, Perez-Cabornero, Pineda, Pinheiro, Pinheiro, Plaschke, Pritchard, Ramsoekh, Rannala, Rannala, Raskin, Reeve, Riel, Ripa, Salovaara, Senter, Shin, Shiri-Sverdlov, Sjursen, Slatkin, Slatkin, Stella, Stella, Sun, Tamura, Tang, Therkildsen, Thiffault, Tomsic, Tomsic, Vahteristo, Valentin, Vasen, Wagner, Wimmer   +101 more
core   +1 more source

Inaccuracy of Ureteroscopic Biopsy in Upper Tract Urothelial Carcinoma Can Lead to False Therapeutic Decisions: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Do not rely solely on negative endoscopic biopsies when diagnosing upper tract urothelial carcinoma (UTUC). Repeat ureteroscopy with biopsy if initial results are negative to reduce false negatives. Frozen section analysis (FSA) can provide rapid intraoperative confirmation and guide treatment decisions.
Ayoub Hidayat‐Allah, Frank Friedersdorff   +1 more
wiley   +1 more source

A rare case of colonic adenocarcinoma in a pediatric patient

JPGN Reports, Volume 6, Issue 4, Page 400-403, November 2025.
Abstract Lynch syndrome (LS) is an autosomal dominant condition caused by a loss of function in the deoxyribonucleic acid mismatch repair system. This case report presents a 17‐year‐old male with abdominal pain, weight loss, and anemia who was diagnosed with LS‐associated adenocarcinoma of the colon in the setting of a mutS homolog 6 genetic mutation ...
Christine Kaba, Kelsey Chatman, Nicole Hames, Jose E. Velazquez Vega, Hillary Bashaw   +4 more
wiley   +1 more source

Malignant phyllodes tumor in Lynch syndrome: a case report

Journal of Medical Case Reports, 2019
Background Lynch syndrome, or hereditary nonpolyposis colorectal cancer, is an autosomal dominant genetic syndrome that predisposes individuals to multiple cancer types.
Shayma Kazmi, Steven Wagner, Rebecca Heintzelman, Melanie Corbman   +3 more
doaj   +1 more source

Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation [PDF]

, 2018
Lynch syndrome is one of the most common hereditary colorectal cancer (CRC) syndrome and is caused by germline mutations of MLH1, MSH2 and more rarely MSH6, PMS2, MLH3 genes.
Benhattar, Jean, Bouzourene, Hanifa, Hutter, Pierre, Losi, Lorena, Martin, Patricia   +4 more
core