Results 121 to 130 of about 31,297 (199)

Utility of hERG Assays as Surrogate Markers of Delayed Cardiac Repolarization and QT Safety [PDF]

, 2006
Gary A. Gintant, Zhi Su, Ruth L. Martin, Bryan F. Cox   +3 more
openalex   +1 more source

Homozygous Missense N629D hERG (KCNH2) Potassium Channel Mutation Causes Developmental Defects in the Right Ventricle and Its Outflow Tract and Embryonic Lethality [PDF]

, 2008
Guo Qi Teng, Xian Zhao, James P. Lees‐Miller, F. Russell Quinn, Pin Li, Derrick E. Rancourt, Barry London, James C. Cross, Henry J. Duff   +8 more
openalex   +1 more source

KCNQ1 Expression Modulates Herg Current by Removing Inactivation [PDF]

, 2014
Carlos G. Vanoye, Richard C. Welch, Alfred L. George   +2 more
openalex   +1 more source

Analysis of the human KCNH2(HERG) gene: Identification and characterization of a novel mutation Y667X associated with long QT syndrome and a non-pathological 9 bp insertion Communicated by: Mark H. Paalman Online Citation: Human Mutation, Mutation in Brief #325 (2000) Online http://journals.wiley.com/1059-7794/pdf/mutation/325.pdf [PDF]

, 2000
Aimée Paulussen, Ping Yang, Menelas N. Pangalos, Peter Verhasselt, Roger Marrannes, Christel Verfaille, Ine Vandenberk, Raf Crabbe, Frank Konings, Walter Luyten, Martin Armstrong   +10 more
openalex   +1 more source

A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes

, 1997
Shimin Wang, Shuguang Liu, Michael J. Morales, Harold C. Strauss, Randall L. Rasmusson   +4 more
openalex   +2 more sources

Molecular Determinants in K+ Channel hERG Inactivation Gating [PDF]

, 2012
David A. Köpfer, Ulrike Hahn, Iris Ohmert, Gert Vriend, Olaf Pongs, Bert L. de Groot, Ulrich Zachariae   +6 more
openalex   +1 more source

Molecular Determinants of Pentamidine-Induced hERG Trafficking Inhibition [PDF]

, 2011
Adrienne T. Dennis, Lu Wang, Hanlin Wan, Drew Nassal, Isabelle Deschênes, Eckhard Ficker   +5 more
openalex   +1 more source

Reassessing the Conduct of Patch Clamp Cardiac Ion Channel Assays to Improve Nonclinical Data Translation to Clinical ECG Changes and Proarrythmia Risk. [PDF]

Clin Transl Sci
Alvarez Baron C, Zhao J, Guo D, Mistry S, De Palma R, Ismaiel OA, Wu WW.   +6 more
europepmc   +1 more source

HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium [PDF]

, 2000
Alessia Cherubini, Gianluigi Taddei, Olivia Crociani, Milena Paglierani, Anna Maria Buccoliero, Luc Fontana, Ivo Noci, P Borri, Elena Borrani, Massimo Giachi, Andrea Becchetti, Barbara Rosati, Enzo Wanke, Massimo Olivotto, Annarosa Arcangeli   +14 more
openalex   +1 more source

KCNH2-L693P Causes Long QT Syndrome Type 2 Through hERG Channel Dysfunction: Functional Validation of a Variant of Uncertain Significance. [PDF]

Mol Genet Genomic Med
Zheng XF, Chen Q, Lu XT, Dai HL, Guang XF.   +4 more
europepmc   +1 more source