Results 131 to 140 of about 17,722 (214)

Off-label use of chloroquine, hydroxychloroquine, azithromycin and lopinavir/ritonavir in COVID-19 risks prolonging the QT interval by targeting the hERG channel. [PDF]

Eur J Pharmacol, 2021
Zequn Z, Yujia W, Dingding Q, Jiangfang L.   +3 more
europepmc   +1 more source

Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block. [PDF]

PLoS One, 2020
Tran PN, Sheng J, Randolph AL, Baron CA, Thiebaud N, Ren M, Wu M, Johannesen L, Volpe DA, Patel D, Blinova K, Strauss DG, Wu WW.   +12 more
europepmc   +1 more source

Probucol-induced hERG Channel Reduction can be Rescued by Matrine and Oxymatrine in vitro. [PDF]

Curr Pharm Des, 2020
Shi YQ, Fan P, Zhang GC, Zhang YH, Li MZ, Wang F, Li BX.   +6 more
europepmc   +1 more source

The macrolide drug erythromycin does not protect the hERG channel from inhibition by thioridazine and terfenadine. [PDF]

Physiol Rep, 2020
El Harchi A, Butler AS, Zhang Y, Dempsey CE, Hancox JC.   +4 more
europepmc   +1 more source

Insights into Hepatic, Neuronal, and hERG Channel Safety of Plant-Derived Active Compounds. [PDF]

J Xenobiot
Kasemnitichok Y, Lee S, Kwon OB, Plengsuriyakarn T, Na-Bangchang K.   +4 more
europepmc   +1 more source

Aminoglycosides restore truncated HERG channels [PDF]

European Heart Journal, 2013
openaire   +1 more source

Harnessing AlphaFold to reveal hERG channel conformational state secrets. [PDF]

Elife
Ngo K, Yang PC, Yarov-Yarovoy V, Clancy CE, Vorobyov I.   +4 more
europepmc   +1 more source

hERG Channel Blockade and Antagonistic Interactions of Three Steroidal Alkaloids from <i>Fritillaria</i> Species. [PDF]

Molecules
Lu H, Hao T, Zhang Z, Jiang C, Xu J, Stalin A, Zhao W.   +6 more
europepmc   +1 more source

KCNH2-L693P Causes Long QT Syndrome Type 2 Through hERG Channel Dysfunction: Functional Validation of a Variant of Uncertain Significance. [PDF]

Mol Genet Genomic Med
Zheng XF, Chen Q, Lu XT, Dai HL, Guang XF.   +4 more
europepmc   +1 more source

LncRNA MALAT1/Calpain-1 Axis in ATO Induced hERG Channel Deficiency. [PDF]

Drug Des Devel Ther
Yan C, Li Y, Li X, Li Y, Zhang Y, Sun J, Ding Q, Zhao X, Li B.   +8 more
europepmc   +1 more source