Results 131 to 140 of about 1,529,868 (197)

Exploring the Role of Metabolites in Torsadogenic Risk Assessment: A Text-Mining Approach. [PDF]

Turk J Pharm Sci
Bilgin E, Tuğcu G, Aydın A.
europepmc   +1 more source

Lipid-dependent regulation of Kv10.1 in cancer: implications of membrane remodeling for channel function and pharmacology. [PDF]

Front Pharmacol
Phuong NV, Stary-Weinzinger A.
europepmc   +1 more source

Dynamical Nonequilibrium Molecular Dynamics Simulations Reveal Atomistic Steps of C-Type Inactivation in Cardiac hERG Channels. [PDF]

J Am Chem Soc
Costa F, Bassetto C, Bezanilla F, Giacomello A.   +3 more
europepmc   +1 more source

Nanodelivery of Brucine in Myocardial Ischemia-Reperfusion Injury: Mitochondrial PANoptosis, Cardiotoxicity, and Translational Barriers. [PDF]

Int J Nanomedicine
Guo Y, Bao R, Fu Y, Meng Y, Zhang L, An Y, Wang X.   +6 more
europepmc   +1 more source

Personalized <i>in silico</i> modeling of cardiac ion channel variants to predict drug-induced proarrhythmia risk. [PDF]

Front Physiol
Henedi A, Cherkaoui J, Camara Dit Pinto S, Levine SM, Cherkaoui M, Gallo NR, Benzeroual KE.   +6 more
europepmc   +1 more source

Integrating AI and Molecular Modeling for Structural Prediction of a Closed-Pore State of the hERG Channel. [PDF]

J Chem Inf Model
Upex C, Osborne T, Biglino G, Hancox JC, Corey RA.   +4 more
europepmc   +1 more source

25 Years of Cardiac Ion Channel QSAR: From hERG Dominance to Multi-Channel Modeling. [PDF]

J Chem Inf Model
Iwan M, Grisoni F, Pentina A, Garcia de Lomana M, Roncaglioni A.   +4 more
europepmc   +1 more source

α-mannosidase I-dependent N-linked glycosylation affects hERG channel functional availability during reactivation. [PDF]

J Physiol Sci
Wei M, Sun H, Yin Y, Liu Y, Wang P, Yoshimura K, Kume S, Kurokawa T, Ono K, Ding L, Zheng M.   +10 more
europepmc   +1 more source

hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine. [PDF]

J Am Heart Assoc, 2015
Melgari D, Brack KE, Zhang C, Zhang Y, El Harchi A, Mitcheson JS, Dempsey CE, Ng GA, Hancox JC.   +8 more
europepmc   +1 more source

Forward genetics reveals a conserved CNBHD-CNBHD interface that restrains EAG channel activation to regulate sleep. [PDF]

PLoS Genet
Huang X, Kannan S, Robertson GA, Wang H.
europepmc   +1 more source