Results 161 to 170 of about 12,393 (207)

QT interval prolongation: clinical assessment, risk factors and quantitative pharmacological considerations. [PDF]

J Pharmacokinet Pharmacodyn
Gotta V, Donner B.
europepmc   +1 more source

AI-Augmented Iterative Screening of Libraries Against RNA Targets (AISLAR) Boosts Discovery of SAR-Tractable RNA Binders and Rational Analog Design. [PDF]

Small Sci
Hattori H, Otsu M, Imai K, Narahara M, Kondo J, Shino A, Morishita EC.   +6 more
europepmc   +1 more source

Improving hERG Cardiotoxicity Prediction via SMILES Transformer, Molecular Fingerprints, and Layer-Wise Self-Adaptive Graph Attention Network. [PDF]

ACS Omega
Beidja C, Bousselham A, En-Naimani Z, Mestari M.   +3 more
europepmc   +1 more source

Discovery of a novel broad-spectrum inhibitor against influenza virus A. [PDF]

Virol J
Yu R, Li P, Shen R, Fei W.
europepmc   +1 more source

Characterization of Intrabodies Targeting the hERG Potassium Channel

, 2019
openaire   +2 more sources

Cardiovascular adverse effects of common non-oncologic medications: from mechanisms to clinical management. [PDF]

Eur Heart J Cardiovasc Pharmacother
Bahit MC, Agudo-Quilez P, Zamorano J, Gibson CM.   +3 more
europepmc   +1 more source

Optical control of the cardiac rhythm with photoswitchable Na_V1.5 channel blockers. [PDF]

Nat Commun
Liu S, Guan W, Li Z, Wang W, Song H, Li J, Hou J, Wang H, Xiong J, Yang M, Yan N, Tian X, Li H, Huang Z.   +13 more
europepmc   +1 more source

The exquisite link between potassium homeostasis regulation and cardiovascular health: exploration and analysis. [PDF]

Front Physiol
Wang C, Huang X, Zhang Z, Lin D, Huang S.   +4 more
europepmc   +1 more source

An Integrated Nonclinical and Clinical Risk Assessment of the Effects of Investigational ATRi Tuvusertib on QTc Interval in Patients With Solid Tumors. [PDF]

Clin Transl Sci
Mukker JK, Yap TA, Tolcher AW, de Bono JS, Plummer R, Grosser G, van Amsterdam C, Schieferstein H, Witjes H, Diderichsen PM, Krebs-Brown A, Gao W, Strotmann R, Szucs Z, Gounaris I, Venkatakrishnan K.   +15 more
europepmc   +1 more source