Results 1 to 10 of about 375,473 (301)
Genome-Wide Association of Heroin Dependence in Han Chinese. [PDF]
PLoS ONE, 2016 Drug addiction is a costly and recurring healthcare problem, necessitating a need to understand risk factors and mechanisms of addiction, and to identify new biomarkers.
Gursharan Kalsi +12 more
doaj +9 more sources
Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence. [PDF]
PLoS ONE, 2013 BACKGROUND: Heroin dependence is a debilitating psychiatric disorder with complex inheritance. Since the dopaminergic system has a key role in rewarding mechanism of the brain, which is directly or indirectly targeted by most drugs of abuse, we focus on ...
Andrea Vereczkei +7 more
doaj +9 more sources
Association analysis of GABRB3 promoter variants with heroin dependence. [PDF]
PLoS ONE, 2014 GABRB3 encoding the β3 subunit of GABAA receptor has been implicated in multiple neuropsychiatric disorders, including substance abuse. Previous studies reported that SNPs at the 5' regulatory region of GABRB3 could regulate GABRB3 gene expression and ...
Chia-Hsiang Chen +2 more
doaj +3 more sources
Allelic and genotypic associations of
Behavioral and Brain Functions, 2007 Background Conflicting associations with heroin dependence have been found involving the A1 allele of dopamine D2 receptor gene (DRD2) TaqI A polymorphism.
Calafell Francesc +9 more
doaj +3 more sources
Buprenorphine for the treatment of heroin dependence [PDF]
Drug and Alcohol Review, 2001 (2001). Buprenorphine for the treatment of heroin dependence. Drug and Alcohol Review: Vol. 20, No. 1, pp. 5-7.
Alison Ritter
openalex +3 more sources
Methadone Treatment for Heroin Dependence [PDF]
, 2018 In substitution therapy for treatment of heroin addiction, methadone is the synthetic opioid agonist of first choice. Methadone doses vary depending on addict profile established by repeated evaluation.
Anne Marie Ciobanu +5 more
openaire +5 more sources
Cost-effectiveness of buprenorphine and naltrexone treatments for heroin dependence in Malaysia. [PDF]
PLoS ONE, 2012 To aid public health policymaking, we studied the cost-effectiveness of buprenorphine, naltrexone, and placebo interventions for heroin dependence in Malaysia.We estimated the cost-effectiveness ratios of three treatments for heroin dependence. We used a
Jennifer Prah Ruger +4 more
doaj +3 more sources
Chronic Heroin Dependence Leading to Adrenal Insufficiency [PDF]
Case Reports in Endocrinology, 2014 Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on
Gautam Das
doaj +4 more sources
Opioid Receptors Gene Polymorphism and Heroin Dependence in Iran [PDF]
Basic and Clinical Neuroscience, 2018 Introduction: Genes often have multiple polymorphisms that interact with each other and the environment in different individuals. Variability in the opioid receptors can influence opiate withdrawal and dependence.
Sara Soleimani Asl +7 more
doaj +2 more sources
The Professional Medical Journal, 2014 Objective: To determine the frequency and level of family support in Heroin Dependent patients presenting with 1st treatment and also the patients presenting with relapses. Study design: A descriptive study. Place & duration of study: The study was conducted in the Department of Psychiatry & Behavioral Sciences, Nishtar Hospital, Multan from ...
Niaz Maqsood +3 more
openalex +4 more sources