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Pioneer factors in viral infection
Pioneer factors are transcription factors sharing the fascinating ability to bind to compact chromatin and thereby alter its transcriptional fate. Most pioneer factors are known for their importance during embryonic development, for instance, in inducing
Eva Neugebauer+9 more
doaj +1 more source
Pathogenesis and virulence of herpes simplex virus
Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital herpes, herpes stromal keratitis, meningitis and encephalitis.
Shuyong Zhu, A. Viejo-Borbolla
semanticscholar +1 more source
Herpes Simplex Virus Cell Entry Mechanisms: An Update
Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and show an extraordinary ability to bind more than one receptor on the host ...
Krishnaraju Madavaraju+4 more
semanticscholar +1 more source
Seroprevalence of Herpes Simplex Virus type-1antibodies (IgM,IgG) in smokers in Kirkuk city-Iraq
Herpes Simplex Virus type-1 (HSV-1) is classified in the α-herpes virus group of the Herpesviridae and HSV-1 infections are very common in the human population. The objective of this study is to determine the prevalence of anti-herpes simplex virus type-
Lezan Medhat Mohammed Zangana
doaj +1 more source
Herpes simplex virus: global infection prevalence and incidence estimates, 2016
Objective To generate global and regional estimates for the prevalence and incidence of herpes simplex virus (HSV) type 1 and type 2 infection for 2016.
Charlotte James+6 more
semanticscholar +1 more source
Relationship Between Pemphigus Vulgaris Severity and PCR-positive Herpes Simplex Virus
Pemphigus vulgaris is a rare autoimmune skin disease. Although herpes simplex virus has been associated with autoimmune diseases, evidence regarding its association with pemphigus vulgaris exacerbations is scarce. This retrospective cohort study aimed to
Sharon Baum+7 more
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Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer’s Disease
Strong evidence has emerged recently for the concept that herpes simplex virus type 1 (HSV1) is a major risk for Alzheimer’s disease (AD). This concept proposes that latent HSV1 in brain of carriers of the type 4 allele of the apolipoprotein E gene (APOE-
R. Itzhaki
semanticscholar +1 more source
Herpes Simplex Virus Latency Is Noisier the Closer We Look
During herpes simplex virus (HSV) latency, the viral genome is harbored in peripheral neurons in the absence of infectious virus but with the potential to restart infection. Advances in epigenetics have helped explain how viral gene expression is largely
Navneetkumar R. Singh, D. Tscharke
semanticscholar +1 more source
The purposes of the study were to assess the usefulness of simultaneously amplifying herpes simplex virus 1 and 2, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and human herpesvirus 6 DNA in various clinical specimens and to analyze ...
Priavali Efthalia+4 more
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Ocular manifestations of herpes simplex virus.
PURPOSE OF REVIEW To review ocular manifestations and complications of herpes simplex virus (HSV) and discuss recent advancements in diagnostic and treatment strategy.
Gabriel S. Valerio, Charles C. Lin
semanticscholar +1 more source