Results 141 to 150 of about 85,707 (260)
Heterochromatin drives compartmentalization of inverted and conventional nuclei
M. Falk +10 more
semanticscholar +1 more source
ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung +7 more
wiley +1 more source
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė +10 more
wiley +1 more source
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
Masashi Narita +8 more
semanticscholar +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin
Christèle Maison +3 more
openalex +1 more source
MeCP2 links heterochromatin condensates and neurodevelopmental disease
Charles H. Li +19 more
semanticscholar +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Epigenetic Regulation of Nuclear Lamina-Associated Heterochromatin by HAT1 and the Acetylation of Newly Synthesized Histones [PDF]
Liudmila V. Popova +8 more
openalex +1 more source

