Results 141 to 150 of about 70,860 (329)

A General Group Testing Strategy for Discovering Chemical Cooperativity

Angewandte Chemie, EarlyView.
A combinatorial design theory‐based group testing strategy coupled with luminescence screening to uncover cooperative interactions in a large combinatorial space. Iterative deconvolution identifies reactive molecular pairs and enables the discovery of trifluoromethylthiolation (SCF3) reagents.
Philipp M. Pflüger, Felix Katzenburg, Frederik Sandfort, Michael Teders, Adrián Gómez‐Suárez, Eric A. Standley, Matthew N. Hopkinson, Constantin G. Daniliuc, Andreas Heuer, Frank Glorius   +9 more
wiley   +2 more sources

Crystal Structure of 4′-Phenyl-1′,4′-Dihydro-2,2′:6′,2″-Terpyridine: An Intermediate from the Synthesis of Phenylterpyridine

Crystals
The intermediate compound 4′-phenyl-1′,4′-dihydro-2,2′:6′,2″-terpyridine (pdhtpy) was isolated for the first time during the synthesis of 4′-phenyl-2,2′:6′,2″-terpyridine (ptpy) and characterised by single-crystal X-ray diffraction.
Alexander Sedykh, Maksim Zhernakov, Mariia Becker, Dirk G. Kurth, Klaus Müller-Buschbaum   +4 more
doaj   +1 more source

Double E─H Bond Activation of Ammonia and Water by Cyclic Gallaphosphene L(OCP)GaPGaL

Angewandte Chemie, EarlyView.
Cyclic gallaphosphene 1 undergoes a twofold E─H bond activation with ammonia and water via a beneficial interplay between the polar “GaPGa” unit and the electrophilic nature of the C center in the bridging PCO unit, yielding six‐membered heterocycles 2 and 3, in which both nucleophilic phosphorus atoms are protonated.
Mahendra K. Sharma, Christoph Wölper, Gebhard Haberhauer, Stephan Schulz   +3 more
wiley   +2 more sources

Mechanism of the Photodecomposition of Stable Triarylmethyl Radicals

Angewandte Chemie, EarlyView.
Photolysis of luminescent chlorinated trityl radicals was studied with density functional theory and the decomposition products were isolated and characterized. It proceeds by a 5‐electron electrocyclization then a 1,8‐sigmatropic chloride shift, forming non‐emissive, less stable fluorenyl radicals.
Hannah E. Hackney, Claude Y. Legault, Hatem M. Titi, Dmytro F. Perepichka   +3 more
wiley   +2 more sources

Predictive, Data‐Driven Design of Red‐Light Photoredox Catalysts for C─Heteroatom Bond Formation

Angewandte Chemie, EarlyView.
From redox numbers to red light: Donor oxidation and core reduction potentials predict E0‐0 in cyanoarene dyes, guiding selection of an efficient red‐light catalyst, 4MeODPATPN (PC13). Under 620 nm light, PC13 facilitates Ni‐catalyzed C─heteroatom cross‐couplings (C─N, C─O, C─S) with high functional‐group tolerance and reduced hydrodehalogenation ...
Amir Gizatullin, Tingting Yuan, Sascha Grotjahn, Luigi Cavallo, Burkhard König, Chen Zhu, Magnus Rueping   +6 more
wiley   +2 more sources

Mild Generation of Highly Nucleophilic N‐Heterocyclic Carbene Boryl Anion From Neutral sp2–sp3 Diboron Reagents and Its Applications in Nucleophilic Borylation

Angewandte Chemie, EarlyView.
A less hindered and highly nucleophilic N‐heterocyclic carbene (NHC) boryl anion is generated at room temperature by reacting sp2–sp3 diboron reagent (NHC)BH2Bpin with KOtBu. This highly reactive anion demonstrates broad reactivity with various electrophiles, including those traditionally considered inert, enabling their efficient borylation.
Weixuan Sun, Peiqi Zhang, Hairong Lyu
wiley   +2 more sources

Synthesis of some isoxazoline, isoxazole and pyrazole carboxylic acids as the precursors of new 1,2-diacyl-1-alkylhydrazines [PDF]

, 2013
A number of isoxazoline, isoxazole and pyrazole carboxylic acids or their esters has been synthesized via the 1,3-dipolar cycloaddition of corresponding nitrile oxides or diazomethane to unsaturated dipolarophiles.
Antonevich, I. P., Katok, Ya. M.
core  

Molecular Electrocatalyst Enables Direct Electrochemical Capture and Conversion of CO2 up to Atmospheric Concentration

Angewandte Chemie, EarlyView.
A molecular manganese electrocatalyst enables the direct electrochemical capture and conversion of dilute CO2 (1% – 0.2%) to CO with nearly unit Faradaic efficiency, achieving high efficiency even at atmospheric concentrations (420 ppm). By bypassing energy‐intensive pre‐concentration steps, this integrated approach highlights a sustainable pathway for
Mattia Vettori, Federico Franco, Sergio Fernández, Guillem Pey, Vlad Martin Diaconescu, Josep M. Luis, Julio Lloret‐Fillol   +6 more
wiley   +2 more sources

2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists

, 2008
Brock T. Shireman, Curt A. Dvorak, Dale A. Rudolph, Pascal Bonaventure, Diane Nepomuceno, Lisa Dvorak, Kirsten L. Miller, Timothy W. Lovenberg, Nicholas I. Carruthers   +8 more
openalex   +1 more source

Arylhydrazines: Convenient Homogeneous Reductants for Scalable Cross‐Coupling

Angewandte Chemie, EarlyView.
Reductive cross‐couplings enable efficient C–C bond formation but are limited by the heterogeneity of Zn or costly reagents like TDAE. We report arylhydrazines as inexpensive, convenient reductants for Ni‐catalyzed sp2–sp3 coupling of aryl halides and secondary alkyl iodides. Mechanistic studies support hydrazine‐mediated NiII reduction for a NiI/NiIII
Nils Kurig, David A. Cagan, Kaid C. Harper, Yu Kawamata, Donna G. Blackmond, Phil S. Baran   +5 more
wiley   +2 more sources