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Heterocycles in Medicinal Chemistry [PDF]
Molecules, 2019 Heteroatoms constitute a very common fragment of a number of active pharmaceutical ingredients as well as excipients; from the point of view of significance, it is all the same if these are isosterically/bioisosterically replaced carbons/carbon ...
J. Jampílek
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Sodium-mediated magnesiation of thiophene and tetrahydrothiophene : structural contrasts with furan and tetrahydrofuran [PDF]
, 2010 Sulfur-containing heterocycles are currently attracting agreat deal of interest in several diverse fields. For instance, substituted tetrahydrothiophenes have received considerable attention due to their extremely wide-ranging chemical and biological ...
, EPSRC (Funder) +4 more
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Molecules, 2020 Aromatic heterocycles are ubiquitous building blocks in bioactive natural products, pharmaceutical and agrochemical industries. Accordingly, the carborane-fused heterocycles would be potential candidates in drug discovery, nanomaterials ...
Ke Cao +7 more
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How Not to Discover a New Reagent. The Evolution and Chemistry of Woollins' Reagent [PDF]
, 2012 The pathways in research can be complex. This review provides a personal account of the winding scientific and funding road that led to Woollins' reagent.
Woollins, J. Derek
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Green Processing and Synthesis, 2019 Nature and nanotechnology have not yet achieved a lucid correlation in the field of science but together they have exhibited immense potential towards the advancement and modification in future science and technology.
Fowsiya J. +7 more
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E-Journal of Chemistry, 2010 The reaction rate of Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an aldehyde, active methylene compound, L-proline and chlorobenzene with a commercial microwave oven.
Shubha Jain +3 more
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An electrochemical gram-scale protocol for pyridylation of inert N-heterocycles with cyanopyridines
STAR Protocols, 2022 Summary: Here, we present a protocol to decyanopyridate inert N-heterocycles access to N-fused heterocycles via the mechanism of dual proton-coupled electron transfer (PCET).
Cong Niu +6 more
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Diquaternary Ammonium Compounds in Zeolite Synthesis: Cyclic and Polycyclic N-Heterocycles Connected by Methylene Chains [PDF]
, 2009 An additional dimension has been added to our long-standing studies in high silica zeolite synthesis via a guest/host synergism. We have created and studied the impact of making symmetric diquaternary ammonium compounds, by varying the chain length ...
Burton, Allen W. +3 more
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β-Functionalization of Saturated Aza-Heterocycles Enabled by Organic Photoredox Catalysis.
ACS Catalysis, 2021 The direct β-functionalization of saturated aza-heterocycles has remained a synthetic challenge because of the remote and unactivated nature of β-C-H bonds in these motifs.
Natalie Holmberg-Douglas +4 more
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Recent Advances in the Synthesis of Heterocycles via Reactions Involving Elemental Sulfur
Advanced Synthesis and Catalysis, 2020 It is well known that heterocycles are among the most significant molecules for everyday life, ranging from natural products and bioactive substances to functional materials.
T. Nguyen
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