Results 1 to 10 of about 128,452 (331)

Recent Advancements in Photocatalytic Synthesis of Five Membered Nitrogen Heterocycles and Their Derivatives [PDF]

open access: yesMolecules
Photocatalytic synthesis of heterocycles has emerged as a versatile strategy in organic synthesis. Among various heterocycles, five membered heterocycles such as pyrroles, indoles and their derivatives have great significance based on their ...
Zeeshan Haider   +2 more
doaj   +2 more sources

Chiral hypervalent iodine catalyzed stereoselective skeletal editing of pyrimidine fused heterocycles [PDF]

open access: yesNature Communications
In the realm of molecular construction, the skeletal editing techniques of heterocyclic compounds demonstrate unique efficiency, particularly in synthesizing molecular structures that are challenging to obtain through traditional synthetic methods ...
Wen-Wu Sun, Yi-Bing Xie, Bin Wu
doaj   +2 more sources

Construction of Benzenesulfonamide Derivatives via Copper and Visible Light-induced Azides and S(O)2–H Coupling

open access: yesMolecules, 2022
We here have developed an S(O)2–N coupling between phenylsulfinic acid derivatives and aryl azides by dual copper and visible light catalysis. In this efficient and mild pathway, the reaction produces sulfonamide compounds under redox-neutral condition ...
Zhipeng Liang, Ya-Nan Wu, Yang Wang
doaj   +1 more source

6-Endo-dig cyclization: Flexible enforce to develop synthetic route in organic syntheses

open access: yesResults in Chemistry, 2023
The organic ring closure reaction of diverse acyclic compounds is governed mostly by the Baldwin rule. The ring closure compounds shows emergent application.
Vembu Yogeshwaran   +3 more
doaj   +1 more source

The Role of Five-Membered Heterocycles in the Molecular Structure of Antibacterial Drugs Used in Therapy

open access: yesPharmaceutics, 2023
Five-membered heterocycles are essential structural components in various antibacterial drugs; the physicochemical properties of a five-membered heterocycle can play a crucial role in determining the biological activity of an antibacterial drug.
Aura Rusu   +3 more
doaj   +1 more source

Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms

open access: yesMolecules, 2021
Coumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules ...
Eslam Reda El-Sawy   +2 more
doaj   +1 more source

Novel N-Arylsulfonylindoles Targeted as Ligands of the 5-HT6 Receptor. Insights on the Influence of C-5 Substitution on Ligand Affinity

open access: yesPharmaceuticals, 2021
A new series of twenty-two C-5 substituted N-arylsulfonylindoles was prepared with the aim of exploring the influence of C-5 substitution on 5-HT6 receptor affinity. Eleven compounds showed moderate to high affinity at the receptor (Ki = 58–403 nM), with
Loreto Arrieta-Rodríguez   +8 more
doaj   +1 more source

Structure and Stability of Aromatic Nitrogen Heterocycles Used in the Field of Energetic Materials

open access: yesMolecules, 2020
Understanding the stabilization of nitrogen heterocycles is critical in the field of energetic materials and calls for innovative knowledge of nitrogen aromatics.
He-Hou Zong   +4 more
doaj   +1 more source

Synthesis of Phosphorus(V)-Substituted Six-Membered N-Heterocycles: Recent Progress and Challenges

open access: yesMolecules, 2023
Heterocycles functionalized with pentavalent phosphorus are of great importance since they include a great variety of biologically active compounds and pharmaceuticals, advanced materials, and valuable reactive intermediates for organic synthesis ...
Yulia Volkova, Igor Zavarzin
doaj   +1 more source

Synthesis of Polyhedral Borane Cluster Fused Heterocycles via Transition Metal Catalyzed B-H Activation

open access: yesMolecules, 2020
Aromatic heterocycles are ubiquitous building blocks in bioactive natural products, pharmaceutical and agrochemical industries. Accordingly, the carborane-fused heterocycles would be potential candidates in drug discovery, nanomaterials ...
Ke Cao   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy