Results 91 to 100 of about 9,440 (222)

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Heterogeneous nuclear ribonucleoproteins (hnRNPs): An emerging family of autoantigens in rheumatic diseases [PDF]

, 1998
In eukaryotic cells, mature mRNA molecules are produced through the extensive post-transcriptional processing of primary transcripts assembled in ribonucleoprotein complexes. Twenty polypeptides, termed heterogeneous nuclear ribonucleoproteins or hnRNPs,
R. Caporali, C. Montecucco, G. Biamonti, CAPORALI, ROBERTO, MONTECUCCO, CARLOMAURIZIO, C. Ghigna   +5 more
core  

Expression pattern of heterogeneous nuclear ribonucleoprotein H1 and heterogeneous nuclear ribonucleoprotein K in Myeloproliferative neoplasms

The Egyptian Journal of Haematology
Background Self-renewing hematopoietic stem cells differentiate into myeloid or lymphoid lineages. Myeloproliferative neoplasms (MPNs) are a group of disorders characterized by aberrant proliferation of one or more terminal myeloid cell lines.
Fatma M. Helbawi, Sahar A. Elgammal, Yomna R. Mahboub, Alaa A. Elminshawy, Radwa H. Naguib, Aml A. Rayan   +5 more
openaire   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Effect of heterogeneous nuclear ribonucleoprotein U on the migration and proliferation of non-small cell lung cancer cells [PDF]

精准医学杂志
Objective To investigate the effect of heterogeneous nuclear ribonucleoprotein U (hnRNP U) on the migration and proliferation of non-small cell lung cancer (NSCLC) cells.
HE Yangfan, XU Xiaorong, YU Xin, LIU Chunyan, LI Bing
doaj   +1 more source

Covalently Immobilized Lignin–Xanthene Conjugates for Persistent Surface Photochemistry and Self‐Sterilizing Interfaces Under Ambient Visible Light

Macromolecular Rapid Communications, EarlyView.
Bio‐derived lignin–Eosin Y macromolecular networks are developed as visible‐light‐responsive self‐sterilizing coatings that generate reactive oxygen species without leaching. The spray‐coated photopolymerized surfaces exhibit durable antibacterial and antiviral activity under ambient light for extended periods, demonstrating a scalable and sustainable ...
Euna Oh, Surjith Kumaran, Sumin Han, Kiseok Lee, Hyerin Shin, Seokmin Oh, Dae‐Hong Ko, Hyo‐Jick Choi   +7 more
wiley   +1 more source

New insights into trypanosomatid U5 small nuclear ribonucleoproteins [PDF]

, 2011
Several protozoan parasites exist in the Trypanosomatidae family, including various agents of human diseases. Multiple lines of evidence suggest that important differences are present between the translational and mRNA processing (trans splicing) systems
Cicarelli, Regina Maria Barretto [UNESP], Lewis J Greene, Regina MB Cicarelli, José C Rosa, Tatiana F Watanabe, Trevelin, Caroline C. [UNESP], AMBRÓSIO, Daniela L, Trevelin, Caroline C., Watanabe, Tatiana F. [UNESP], VALENTINI, Sandro R, Caroline C Trevelin, Valentini, Sandro Roberto, Marco Túlio A da Silva, TREVELIN, Caroline C, Valentini, Sandro Roberto [UNESP], Laure, Helen J., Cicarelli, Regina M.B., Sandro R Valentini, Helen J Laure, ROSA, José C, Daniela L Ambrósio, Ambrosio, Daniela L. [UNESP], Rosa, Jose C., Cicarelli, Regina Maria Barretto, Greene, Lewis J., CICARELLI, Regina MB, WATANABE, Tatiana F, Valentini, Sandro R., LAURE, Helen J, Ambrósio, Daniela L., da Silva, Marco Tulio A. [UNESP], da Silva, Marco Túlio A., GREENE, Lewis J, Watanabe, Tatiana F., SILVA, Marco Túlio A da, da Silva, Marco Túlio A [UNESP]   +35 more
core   +4 more sources

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

The heterogeneous nuclear ribonucleoproteins I and K interact with a subset of the ro ribonucleoprotein-associated Y RNAs in vitro and in vivo. [PDF]

, 2001
The hY RNAs are a group of four small cytoplasmic RNAs of unknown function that are stably associated with at least two proteins, Ro60 and La, to form Ro ribonucleoprotein complexes.
Fabini, G, Fouraux, M.A., Raijmakers, R., Steiner, G., Hayer, S, Pruijn, G.J.M.   +5 more
core   +1 more source

Linking hnRNP Function to ALS and FTD Pathology

Frontiers in Neuroscience, 2018
Following years of rapid progress identifying the genetic underpinnings of amyotrophic lateral sclerosis (ALS) and related diseases such as frontotemporal dementia (FTD), remarkable consistencies have emerged pointing to perturbed biology of ...
Maria D. Purice, J. Paul Taylor, J. Paul Taylor   +2 more
doaj   +1 more source