Results 91 to 100 of about 48,636 (248)

Measles, mumps and rubella vaccine and heterologous immunity: a way out of the COVID-19 crisis? [PDF]

Sudan J Paediatr, 2022
Shrivastava J, Narang M, Gomber S.
europepmc   +1 more source

Characterization of Immune Responses to RBD‐SD1 Nanoparticle Vaccines Derived From ACE2‐Capable HKU5‐CoV‐2, NeoCoV, and HKU5 Merbecoviruses

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles presenting HKU5, NeoCoV, and HKU5‐CoV‐2 RBD‐SD1 induced strong, cross‐reactive IgG responses in immunized mice. The surrogate virus neutralization test demonstrated strong activity in sera from homologous vaccination. ABSTRACT Recent discoveries of merbecoviruses such as HKU5, NeoCoV, and HKU5‐CoV‐2 that use angiotensin ...
Peter J. Halfmann, Jeong Soo Lee, Augustine Duffy, Tong Wang, Bingcheng Huang, James Z. Kurdi, Ajay Inampudi, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +11 more
wiley   +1 more source

Heterologous immunity induced by 1^st generation COVID-19 vaccines and its role in developing a pan-coronavirus vaccine. [PDF]

Front Immunol, 2022
Patel RS, Agrawal B.
europepmc   +1 more source

Induction and Enhancement of Bacteriocin Production (Review)

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley   +1 more source

Antibody Response after Homologous and Heterologous Prime–Boost COVID-19 Vaccination in a Bangladeshi Residential University Cohort

Vaccines
COVID-19 vaccination strategies, including heterologous prime–boost regimens and additional booster doses, aim to optimize immune responses. However, seroepidemiological studies on immune responses to different COVID-19 vaccine types and schedules remain
Nihad Adnan, Md. Ahsanul Haq, Salma Akter, S. M. Shafiul Alam Sajal, Md. Fokhrul Islam, Taslin Jahan Mou, Mohd. Raeed Jamiruddin, Fatema Tuz Jubyda, Md. Salequl Islam, Jamsheda Ferdous Tuli, Syeda Moriam Liza, Sharif Hossain, Zinia Islam, Sohel Ahmed, Shahad Saif Khandker, Rubel Hossain, Md. Firoz Ahmed, Mohib Ullah Khondoker, Nafisa Azmuda, Md. Anowar Khasru Parvez   +19 more
doaj   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection

Nature Communications
Clinical immunity to malaria can lead to asymptomatic infection, but the underlying mechanisms remain unclear. To examine the development of clinical immunity, we conducted a multi-cohort, repeat controlled human malaria infection (CHMI) study with ...
Mimi M. Hou, Adam C. Harding, Natalie M. Barber, Prasun Kundu, Florian A. Bach, Jo Salkeld, Yrene Themistocleous, Nicola M. Greenwood, Jee-Sun Cho, Jordan R. Barrett, Fay L. Nugent, Thomas A. Rawlinson, Susanne H. Hodgson, Baktash Khozoee, Dylan J. Mac Lochlainn, Rachel E. Cowan, Ian D. Poulton, Megan Baker, Lucy Kingham, Celia H. Mitton, Abigail Platt, Raquel Lopez Ramon, Fernando Ramos Lopez, Merin Thomas, Katherine Skinner, Doris Quinkert, Dimitra Pipini, Amelia M. Lias, Martino Bardelli, Nick J. Edwards, Francesca R. Donnellan, Sumi Biswas, Julian C. Rayner, Carolyn M. Nielsen, Sarah E. Silk, Simon J. Draper, Wiebke Nahrendorf, Philip J. Spence, Angela M. Minassian   +38 more
doaj   +1 more source

Heterologous Immunity of Virus-Specific T Cells Leading to Alloreactivity: Possible Implications for Solid Organ Transplantation. [PDF]

Viruses, 2021
Karahan GE, Claas FHJ, Heidt S.
europepmc   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source