Results 81 to 90 of about 48,636 (248)
How to Employ Trained Immunity and Trained Immunity-Based Vaccines to Inhibit Allergic Inflammation
VaccinesTrained immunity confers protection against subsequent unrelated infections through metabolic and epigenetic reprogramming. Unlike adaptive immunity, trained innate immunity provides broad, non-specific protection against diverse heterologous pathogens ...
Wonho Kim, Dooil Jeoung
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Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
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Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis
Emerging Infectious Diseases, 2002 Prior immunization of hamsters with three heterologous flaviviruses (Japanese encephalitis virus [JEV] SA14-2-8 vaccine, wild-type St. Louis encephalitis virus [SLEV], and Yellow fever virus [YFV] 17D vaccine) reduces the severity of subsequent West Nile
Robert B. Tesh +4 more
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A plant-produced SARS-CoV-2 spike protein elicits heterologous immunity in hamsters. [PDF]
Front Plant Sci, 2023 Margolin E +14 more
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Biotechnology and Bioengineering, EarlyView.Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
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Bulletin of the World Health Organization, 1968 Previous studies on heterologous immunity in mice have indicated that Schistosoma bovis and S. mattheei could be used to limit the severity of infection resulting from subsequent challenge by S. mansoni. These observations have now been extended to study the immunizing effect in rhesus monkeys of both S. mattheei and S.
M A, Amin, G S, Nelson, M F, Soud
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Immune Response of Congenitally Thymusless Mice to Heterologous Erythrocytes
Experimental Biology and Medicine, 1972 SummaryHemagglutinin and hemolysin production by congenitally thymusless (“nude”) mice in response to intraperitoneal injection of 107, 108, 109, or 1010 sheep erythrocytes (SE) was significantly lower than in normal littermate controls. The plaque-forming cell response of nudes was also impaired.
Reed, N D, Jutila, J W
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Pectinase‐Based Bioprocesses for Circular Bioeconomy and Sustainable Industrial Development
Biotechnology and Bioengineering, EarlyView.This picture demonstrates a unified strategy for sustainable pectinase production, focusing on microbial bioproduction, innovative strategies in enzyme engineering (Protein engineering, rational enzyme design, directed evolution and heterologous expression) and various applications in industry, including food, textiles, pulp and paper, agriculture and ...
Nisha Sharma +6 more
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Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines
Biotechnology and Bioengineering, EarlyView.ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt +3 more
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Effects of Grafting on the Structure and Function of Coffee Rhizosphere Microbiome
AgricultureHeterologous double-root grafting represents an effective strategy to mitigate challenges associated with continuous coffee cropping and reduce soil-borne diseases. However, its specific regulatory mechanism remains unclear. Therefore, a field experiment
Yan Sun +9 more
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