Results 71 to 80 of about 60,478 (190)

Arabidopsis heterotrimeric G-protein regulates cell wall defense and resistance to necrotrophic fungi [PDF]

, 2012
The Arabidopsis heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi. The agb1 mutant impaired in the Gβ subunit displays enhanced susceptibility to these pathogens. Gβ/AGB1 forms an obligate dimer with either one of the
Adie, Adjobo-Hermans, Bayer, Bednarek, Berrocal-Lobo, Bischoff, Blakeney, Bohman, Brown, Cantu, Chakravorty, Chen, Denby, Digby, Dische, Ellis, Ferrari, Filisetti-Cozzi, Glawischnig, Grigston, Hernández-Blanco, Huang, Humphrey, Hématy, Johnston, Jones, Joo, Kato, Kato, Kauráková, Kemsley, Kliebenstein, Lease, Levy, Lionetti, Llorente, Llorente, Maeda, Marrari, Mason, Miedes, Mutwil, Neumetzler, Nishitani, Pandey, Persson, Pfalz, Pfalz, Philip, Raiola, Ramírez, Reiter, Rieu, Rogers, Sampedro, Schuhegger, Selvendran, Somerville, Stein, Stevenson, Suharsono, Sánchez-Rodriguez, Sánchez-Vallet, Temple, Thomma, Trusov, Trusov, Trusov, Trusov, Trusov, Ullah, Ullah, van Kan, Vilím, Vogel, Vogel, Wang, Wang, Wilson, Zhang, Zhu   +80 more
core   +2 more sources

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations [PDF]

, 2004
CBS domains are defined as sequence motifs that occur in several different proteins in all kingdoms of life. Although thought to be regulatory, their exact functions have been unknown.
Anis, Miliea, Green, Kevin A., Hardie, D. Grahame, Hawley, Simon A., Norman, David G., Scott, John W., Scullion, Gillian A., Stewart, Greg   +7 more
core   +6 more sources

Ligand-induced dynamics of heterotrimeric G protein-coupled receptor-like kinase complexes.

PLoS ONE, 2017
BackgroundArabidopsis, 7-transmembrane Regulator of G signaling protein 1 (AtRGS1) modulates canonical G protein signaling by promoting the inactive state of heterotrimeric G protein complex on the plasma membrane.
Meral Tunc-Ozdemir, Alan M Jones
doaj   +1 more source

Exocytosis from permeabilized bovine adrenal chromaffin cells is differently modulated by guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta gamma-imido]triphosphate [PDF]

, 1992
1. In bovine adrenal chromaffin cells made permeable either to molecules less than or equal to 3 kDa with alphatoxin or to proteins less than or equal to 150 kDa with streptolysin O, the GTP analogues guanosine 5'-[beta gamma-imido]triphosphate (p[NH]ppG)
Ahnert-Hilger, G., Gratzl, Manfred, Rosenthal, W., Spicher, K., Stecher, B., Wegenhorst, U.   +5 more
core  

G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans. [PDF]

, 2017
G protein-coupled receptors (GPCRs) regulate many animal behaviors. GPCR signaling is mediated by agonist-promoted interactions of GPCRs with heterotrimeric G proteins, GPCR kinases (GRKs), and arrestins.
Aryal, Dipendra K., Benovic, Jeffrey L., Luo, Jiansong, Nass, Richard, Wang, Jianjun, Wetsel, William C.   +5 more
core   +2 more sources

Evaluation of differential qPE9-1/DEP1 protein domains in rice grain length and weight variation

Rice, 2019
Background qPE9–1/DEP1, encoding a G protein γ subunit, has multiple effects on plant architecture, grain size, and yield in rice. The qPE9–1 protein contains an N-terminal G gamma-like (GGL) domain, a putative transmembrane domain, and a C-terminal ...
Xiangbo Li, Quandan Tao, Jun Miao, Zefeng Yang, Minghong Gu, Guohua Liang, Yong Zhou   +6 more
doaj   +1 more source

Mutations in the gene of the Gα subunit of the heterotrimeric G protein are the cause for the brachytic1 semi-dwarf phenotype in barley and applicable for practical breeding

Hereditas, 2017
Background Short-culm mutants have been widely used in breeding programs to increase lodging resistance. In barley (Hordeum vulgare L.), several hundreds of short-culm mutants have been isolated over the years.
Ilka Braumann, Christoph Dockter, Sebastian Beier, Axel Himmelbach, Finn Lok, Udda Lundqvist, Birgitte Skadhauge, Nils Stein, Shakhira Zakhrabekova, Ruonan Zhou, Mats Hansson   +10 more
doaj   +1 more source

Functional selectivity of GPCR-directed drug action through location bias. [PDF]

, 2017
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco, Huang, Bo, Irannejad, Roshanak, Mika, Delphine, Pessino, Veronica, von Zastrow, Mark, Wedegaertner, Philip B.   +6 more
core   +3 more sources

Role of the V2R–βarrestin–Gβγ complex in promoting G protein translocation to endosomes

Communications Biology
Classically, G protein-coupled receptors (GPCRs) promote signaling at the plasma membrane through activation of heterotrimeric Gαβγ proteins, followed by the recruitment of GPCR kinases and βarrestin (βarr) to initiate receptor desensitization and ...
Badr Sokrat, Anthony H. Nguyen, Alex R. B. Thomsen, Li-Yin Huang, Hiroyuki Kobayashi, Alem W. Kahsai, Jihee Kim, Bing X. Ho, Symon Ma, John Little, Catherine Ehrhart, Ian Pyne, Emmery Hammond, Michel Bouvier   +13 more
doaj   +1 more source

Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII [PDF]

, 2008
Regulation of intracellular cyclic adenosine 3’, 5’-monophosphate (cAMP) by multiple pathways enables differential function of this ubiquitous second messenger in a context dependent manner.
Collins, Julie, Davis, Richard, Fraser, Iain D., Jiang, Lily I., Sternweis, Paul C.   +4 more
core   +2 more sources