Results 161 to 170 of about 2,645,999 (191)

Heterotrimeric and small molecular mass GTP-binding proteins of rat brain neuronal and glial nuclei

Journal of Neuroscience Research, 1999
Heterotrimeric and small molecular mass guanine nucleotide binding (GTP-binding) proteins were found in neuronal and glial nuclei isolated from rat brain. Neuronal nuclei bound 0.213 +/- 0.055 pmoles of GTP/microg protein (n = 8) and glial nuclei bound 0.145 +/- 0.038 pmoles of GTP/microg protein (n = 8).
Julian N Kanfer, D G McCartney, Rajinder P Bhullar   +2 more
exaly   +3 more sources

Volatile anesthetics modulate the binding of guanine nucleotides to the α subunits of heterotrimeric GTP binding proteins

European Journal of Pharmacology, 1999
The effects of volatile anesthetics on guanine nucleotide binding to the purified alpha subunits of heterotrimeric GTP binding (G) proteins were studied. At sub-anesthetic doses, halothane, isoflurane, enflurane and sevoflurane inhibit exchange of GTPgammaS for GDP bound to Galpha subunits and markedly enhance the dissociation of GTPgammaS, but fail to
Mario J Rebecchi
exaly   +3 more sources

Heterotrimeric GTP-Binding Proteins

2017
exaly   +2 more sources

Heterotrimeric GTP-binding Proteins

2011
exaly   +2 more sources

Heterotrimeric GTP-binding Proteins

2008
exaly   +2 more sources

Evidence for Heterotrimeric GTP‐Binding Proteins in Toxoplasma gondii

Journal of Eukaryotic Microbiology, 1996
Toxoplasma gondii, an intracellular protozoan parasite, resides within a host‐derived vacuole that is rapidly modified by a parasite‐secreted membranous tubular network. In this study we investigated the involvement of heterotrimeric G proteins in the secretory pathway of T. gondii.
S K, Halonen, E, Weidner, J F, Siebenaller   +2 more
openaire   +2 more sources

Heterotrimeric GTP-binding Proteins in the Lacrimal Acinar Cell Endomembrane System

Experimental Eye Research, 2002
Secretagogues accelerate traffic in the lysosomal and basal-lateral pathways, as well as in the regulated apical secretory pathway, of lacrimal acinar cells. It has been proposed that alterations of protein segregation in compartments where these traffic pathways intersect may influence autoimmune responses.
Limin, Qian, Tao, Yang, Haishan, Chen, Jiansong, Xie, Hongtao, Zeng, Dwight W, Warren, Michaela, MacVeigh, Michele A, Meneray, Sarah F, Hamm-Alvarez, Austin K, Mircheff   +9 more
openaire   +2 more sources

Cytosolic Localization of β3-Subunit of Heterotrimeric GTP Binding Protein in Rat Hearts

Biochemical and Biophysical Research Communications, 1995
The expression of three different subtypes of GTP binding protein beta-subunits (beta 1, beta 2 and beta 3) was examined in rat hearts at both mRNA and protein levels. Among three subtypes, beta 3 mRNA was more abundant in ventricles while beta 1 and beta 2 mRNAs were expressed ubiquitously among ventricles, atria and aortas.
S, Muramoto, T, Murakami, K, Urasawa, H, Kawaguchi, A, Kitabatake   +4 more
openaire   +2 more sources

Activation of Heterotrimeric GTP-Binding Proteins

1999
Guanosine triphosphate- (GTP-) binding proteins constitute a supergene family of proteins that utilize GTP binding and hydrolysis as a chemical switch. These proteins are activated by exchanging bound guanosine diphosphate (GDP) with GTP and are subsequently inactivated by hydrolyzing bound GTP to GDP.1–3 Hence, by shuttling between an inactive, GDP ...
openaire   +1 more source

Growth factor second messenger systems: Oncogenes and the heterotrimeric GTP‐;binding protein connection

Medicinal Research Reviews, 1993
We feel that there is now compelling evidence that the GTP-binding proteins play more than just a coordinating role in the actions of both tyrosine kinase and nontyrosine kinase receptor signal transduction. These similarities appear to represent just a small component of the convergence in the signaling pathways for structurally dissimilar receptor ...
M F, Crouch, I A, Hendry
openaire   +2 more sources