Results 61 to 70 of about 11,723 (175)
Sensory Neuroscience, Volume 2, Issue 1, March 2026.This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo +11 more
wiley +1 more source
Galpha12 Protects Vascular Endothelial Cells from Serum Withdrawal-Induced Apoptosis through Regulation of miR-155 [PDF]
, 2017 PURPOSE: Apoptosis of vascular endothelial cells is a type of endothelial damage that is associated with the pathogenesis of cardiovascular diseases such as atherosclerosis. Heterotrimeric GTP-binding proteins (G proteins), including the alpha 12 subunit
이은직, 이현정
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The FEBS Journal, Volume 293, Issue 6, Page 1681-1707, March 2026.Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk +8 more
wiley +1 more source
Exocytosis in chromaffin cells. Possible involvement of the heterotrimeric GTP-binding protein G(o)
Journal of Biological Chemistry, 1993 The use of non-hydrolyzable analogues of GTP in permeabilized secretory cells suggests that guanine nucleotide-binding regulatory proteins (G proteins) may be involved in regulated exocytosis. Because GTP analogues are known to modulate both monomeric low molecular mass G proteins and heterotrimeric G proteins, we have examined the effect of mastoparan,
N, Vitale +5 more
openaire +2 more sources
Current Plant BiologyHeterotrimeric GTP-binding proteins or G-proteins are pivotal players in the intricate signaling cascades of plant cells, operating through their binding to guanine nucleotides.
Deepak Bhardwaj +8 more
doaj +1 more source
Nuclear and cytoskeletal translocation and localization of heterotrimeric G-proteins
, 2015 Heterotrimeric GTP-binding proteins (G-proteins) are involved in a diverse array of signalling path-ways. They are generally thought to be membrane-bound proteins, which disassociate on receptor activation and binding of GTP.
Crouch, Michael F
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, 1997 The whole-cell patch-clamp membrane capacitance measurement was used to monitor secretory activity in rat melanotrophs, while rab3AL, putative effector domain peptides of Rab3 small GTPases (20–30 kDa), were introduced into cytosol.
Zorec, R +7 more
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Physiological functions of muscarinic receptor M3
, 2023 Muscarinic receptors belong to the family of G-protein coupled receptors. G-proteins are heterotrimeric GTP-binding proteins that transfer signals from receptors to effectors. Effectors change levels of second messengers in the cell.
Urbánková, Anna
core
RGS-PX1, Gap for Gas and a Sorting Nexin in Vesicular Trafficking
, 2001 Heterotrimeric GTP–binding proteins (G proteins) control cellular functions by transducing signals from the outside to the inside of cells. Regulator of G protein signaling (RGS) proteins are key modulators of the amplitude and duration of G protein ...
Huang, Xin-Yun +15 more
core +2 more sources
The human serotonin1A receptor exhibits G-protein-dependent cell surface dynamics [PDF]
, 2006 Seven transmembrane domain G-protein-coupled receptors constitute the largest family of proteins in mammals. Signal transduction events mediated by such receptors are the primary means by which cells communi-cate with and respond to their external ...
Pucadyil, Thomas J. +3 more
core +1 more source